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תמליל

1 7/2008 י"ב/התשס"ט רשומות ISRAEL STATE RECORDS November 26, 2008 כ"ח בחשוון התשס"ט יומן הפטנטים והמדגמים PATENTS AND DESIGNS JOURNAL PATENTS Applications filed Applications accepted Patents granted Patents renewed Patents not in force Patents renewed for 20 years Notices Changes in particulars entered in register Changes in proprietorship Country codes Indices of applications accepted DESIGNS Designs registered Designs renewed Designs void עמוד Page i פטנטים בקשות שהוגשו בקשות שקובלו פטנטים שניתנו פטנטים שחודשו פטנטים שתוקפם פקעו פטנטים שחודשו לעשרים שנה הודעות שינויים בפרטים רשומים בפנקס שינויי בעלות קודים למדינות מפתחות לבקשות שקובלו מדגמים מדגמים שנרשמו מדגמים שחודשו מדגמים שבוטלו 2503

2 ידיעות כלליות מכתבים, מסמכים, וכו' בענייני פטנטים ומדגמים יש לשלוח אל: רשם הפטנטים והמדגמים, רח' הסדנא 4, ירושלים לשכת הפטנטים נמצאת ברח' הסדנא 4, תלפיות, ירושלים והיא פתוחה לציבור בימי חול שאינם ערבי שבת או מועד בין השעות 8:30 ו- 12:30. לשכת הפטנטים מספקת תצלומים של פירוטים ושרטוטים במחיר של 2.50 שקלים בעד כל עמוד או חלק ממנו. אגרות ללשכת הפטנטים מתקבלות אך ורק על ידי תשלום לחשבון הלשכה בבנק הדואר מס' יש להציג קבלת בנק הדואר ללשכה יחד עם הבקשה לפעולה שעבורה האגרה שולמה. GENERAL INFORMATION Letters, documents, etc. concerning Patents and Designs should be addressed to: The Commissioner of Patents and Designs, 4 Hasadnah St., Jerusalem The Patent Office is located at 4 Hasadnah St., Talpiot, Jerusalem and is open to the public on weekdays, except on Fridays or on the eves of holydays, from 08:30 to 12:30 hrs. The Patent Office supplies photocopies of specifications and drawings at the rate of NIS 2.50 per page or part thereof. Fees to the Patent Office can be accepted only by payment to the Postal Bank Account of the Office, No The receipt of the Postal Bank must be presented to the office together with the application for the action for which the fee has been paid. Copyright by the State of Israel. No Extracts may be published except with the permission of the Patent Office. Price per single issue (incl. VAT) : NIS 96. Annual subscription (incl. VAT): NIS 1,152. Available at the Distribution Service of Government Publications, 29 B-Street, Hakirya, Tel-Aviv. זכות היוצרים בתקצירים אלה שמורה למדינת ישראל, אין להעתיק מת קצירים אלה אלא ברשות לשכת הפטנטים. מחיר: לכל חוברת בודדת (כולל מ.ע.מ.). 96 דמי חתימה לשנה (כולל מ.ע.מ.). 1,152 אפשר להשיג אצל: שרות ההפצה של פרסומי הממשלה, רחוב ב' מס' 29, הקריה, תל-אביב. 2504

3 NOTICE UNDER SECTION 16 OF THE PATENTS LAW, In the following there are listed new Applications complying with the Provisions of rule 32(a) of the Patent Regulations, Particulars of the applications are given in the following order: Number and date of application And the first four symbols of the International Classification Title of invention (as proposed by applicant) Applicant הודעה לפי סעיף 16 לחוק הפטנטים תשכ"ז להלן רשימת בקשות חדשות הממלאות אחר הדרישות שנקבעו בתקנה 32 א( ( לתקנות הפטנטים, תשכ"ח 1968 : פרטי הבקשות מובאים לפי סדר זה: מספר הבקשה ותאריך הגשתה וארבעה הסמנים הראשונים של הסיווג הבינלאומי שם האמצאה (כפי שהוצע ע"י המבקש) המבקש Priority right: Convention country Number and date of Foreign application דין קדימה: מדינת האיגוד תאריך ומספר בקשת החוץ International Application Number International Publication Number מספר בקשה בינלאומית מס' פרסום בינלאומי 2505

4 15/11/2007 ALARM SYSTEM DOV BARAK, MARKETING DIVISION NUCLEAR RESEARCH CENTER NEGEV G08B מערכת אזעקה דב ברק, אגף שיווק הקריה למחקר גרעיני 26/05/2006 GENE VECTOR FONDAZIONE TELETHON US 60/ /05/2005 PCT/IB/2006/ WO/2007/ C12N וקטור גני 31/05/2006 AUTOMATED CELL THERAPY SYSTEM KWALATA TRADING LIMITED US 60/ /06/2005 PCT/IL/2006/ WO/2006/ A61K מערכת אוטומטית לטיפול תאי 22/06/2006 USE OF CMP FOR ALUMINUM MIRROR AND SOLAR CELL FABRICATION CABOT MICROELECTRONICS CORPORATION US 11/ /06/2005 PCT/US/2006/ WO/2007/ B24B שימוש בליטוש כימי מכני ליצור מראות אלומינום ותאים סולריים 2506

5 31/05/2006 TRAFFIC PREEMPTION SYSTEM COMMUNICATION METHOD GLOBAL TRAFFIC TECHNOLOGIES, LLC US 11/ /06/2005 PCT/US/2006/ WO/2006/ G08G שיטת תקשורת למערכת זכות קדימה תעבורתית 11/12/2007 A TOOTHBRUSH OREN CHARCHI A46B מברשת שיניים לידיה חיה פיטרו ישראל 12/12/2007 BIT GENERATOR G06F מחולל ביטים 18/12/2007 COATED CEMENTED CARBIDE CUTTING TOOL INSERTS AND METHODS OF MAKING THE SAME SANDVIK INTELLECTUAL PROPERTY AB SE /12/ B23C תותבות מקארביד מודבק מצופה עבור מכשיר חיתוך ושיטות להכנתן 18/12/2007 MULTILAYERED COATED CUTTING TOOL SANDVIK INTELLECTUAL PROPERTY AB SE /12/ B23G מכשיר חיתוך מצופה רב שכבתי 2507

6 18/12/2007 CEMENTED CARBIDE COATED CUTTING TOOL INSERTS WITH TOUGHNESS SANDVIK INTELLECTUAL PROPERTY AB SE /12/ B23H תותבות מצופות מקארביד מודבק עבור מכשיר חיתוך בעלי חוזק 20/12/2007 FLEXIBLE ELECTRIC HEATERS A.H.T. ADVANCED HEATING TECHNOLOGIES LTD F24H מחממים חשמליים גמישים אי.איצ'.טי. אדוונסד היטינג טכנולוג'יז בע"מ 20/12/2007 SYSTEM AND METHOD FOR JOINING NON-TRANSPARENT PARTS BY MEANS OF A RADIATION CURABLE ADHESIVE EROWA AG SE 00088/07 22/01/ E06B מערכת ושיטה לחיבור חלקים לא שקופים באמצעי קרינת ריפוי מדביקה 24/12/2007 ADDING INCENTIVES TO PEER-TO- PEER SYSTEMS YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM G06F הוספת תמריצים למערכות עמית לעמית PEER TO PEER) ( יישום חברה לפיתוח המחקר של האוניברסיטה העברית בירושלים 08/01/ LOW-DRAG SWEPT WINGS ISRAEL AEROSPACE INDUSTRIES LTD. US 60/ /01/2007 B64D כנפיים משוכות בעלות גרר נמוך התעשייה האוירית לישראל בע"מ 2508

7 15/01/2008 METHOD AND SYSTEM FOR THE ACQUISITION OF DATA AND FOR THE DISPLAY OF DATA ISRAEL AEROSPACE INDUSTRIES LTD. US 11/ /01/ G06F שיטה ומערכת לרכישת מידע ולהצגת מידע התעשייה האוירית לישראל בע"מ 25/07/2006 METHOD OF TREATING ISCHEMIA- REPERFUSION INJURY BIOREST LTD. US 11/ /07/2005 PCT/IB/2006/ WO/2007/ A61K שיטה לטיפול בנזק איסכמיה רפרפוזיה ביורסט בע"מ 28/01/2008 A COMMUNICATIONS GATEWAY BETWEEN TWO ENTITIES HISPANO-SUIZA FR /01/ H04B שער לחיבור תקשורתי בין שתי ישויות 01/08/2006 USE OF LIPID CONJUGATES IN CYSTIC FIBROSIS AND APPLICATIONS THEREOF YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM US 60/ /08/2005 US 60/ /03/2006 PCT/US/2006/ WO/2007/ A61K שימוש בתצמידים שומנים לציסטיק פיברוזיס ויישומם יישום חברה לפיתוח המחקר של האוניברסיטה העברית בירושלים 2509

8 04/02/2008 THREAT DETECTION SYSTEM INMANTICA LTD G08B מערכת לזיהוי סיכונים אינמנטיקה בע"מ 06/02/2008 SYSTEM AND METHOD FOR FOR LOW COMPLEXITY SPHERE DECODING FOR SPATIAL MULTIPLEXING MIMO RUNCOM TECHNOLOGIES LTD H04L מערכת ושיטה למפענח SPHERE DECODING בעל סיבוכיות נמוכה עבור ריבוב מרחבי MIMO רנקום טכנולוגיות בע"מ 13/02/2008 A SYSTEM AND METHODS FOR POSITIONING INFORMATION FROM A PLURALITY OF USERS ISHAI, RON G08G מערכת ושיטות למיקום מידע אודות מספר משתמשים רון ישי 14/02/2008 LAMP WITH HEAT-RESPONSIVE DECORATION SHLOMO AVITAL B29C מנורה עם קישוט המגיב לחום שלמה אביטל 14/02/2008 ULTRASONIC SPRAYER SYSTEM AND METHOD U.S. DRYER LTD B06B מרסס אולטראסוני מערכת ושיטה מייבש אולטרסוני בע"מ 2510

9 17/02/2008 FRAMELESS TUBE SEMI-TRAILER FOR FLUID TRANSPORTATION ENERGTEK PRODUCTS LTD B62D גרור ללא מסגרת להובלת נוזל אנרגטק מוצרים בע"מ 17/02/2008 A BUILDING METHOD AND BUILDINGS ISRAEL HIRSHBERG E04G שיטת בנייה ובניינים ישראל הירשברג 18/02/2008 REPORTING CAMERA LIOR ARANYA US 60/ /11/ G08B מצלמת דיווח ליאור ארניה 18/02/ COMPACTING TRASHCAN LIOR ARANYA US 60/ /11/2007 A47J פח דחיסה ליאור ארניה 18/02/2008 A LIQUID DISPENSER ROZENBAUM NAFTALI B65D מנפק נוזלים 18/02/ METHOD AND DEVICE TO TRANSFER DIGITAL DATA UZI EZRA HAVOSHA US 60/ /02/2007 US 60/ /05/ G06F שיטה ומתקן להעברת מידע דיגיטלי עוזי חבושה, עו"ד

10 18/02/2008 APPARATUS AND METHOD FOR INDEPENDENT AXIAL POSITIONAL CONTROL OF MULTIPLE MOTORS REDLER COMPUTERS LTD B25J התקן ושיטה לבקרה של הכוונת ציר עצמאית במערכת בה מנועים מרובים רדלר מחשבים בע"מ 18/02/2008 MECHANICAL DEVICE THAT PROTECTS BABIES BEN-ZION VIDER A47D התקן מכני אשר מגן על תינוקות דר' בן-ציון וידר 18/02/2008 MULTIPURPOSE AQUEOUS PARTS WASHER SAFETY-KLEEN SYSTEMS, INC. US 11/ /03/2007 US 11/ /06/ A47L מכשיר רב תכליתי לשטיפת רכיבים על בסיס מים 18/02/2008 METHOD FOR DETECTING DUPLICATED INSTANCES OF A SOFTWARE LICENSE ALADDIN KNOWLEDGE SYSTEMS LTD US 11/ /02/ H04K שיטה לזיהוי מקרים של שכפול רשיון תוכנה אלדין מערכות ידע בע"מ 18/02/2008 SELF-DEFENSIVE PROTECTED SOFTWARE WITH SUSPENDED LATENT LICENSE ENFORCEMENT ALADDIN KNOWLEDGE SYSTEMS LTD US 11/ /02/ H04K תוכנה מוגנת המגנה על עצמה עם אכיפת רשיון סמויה מושהית אלדין מערכות ידע בע"מ 2512

11 18/02/2008 METHOD FOR DETECTING THAT A PROTECTED SOFTWARE PROGRAM IS CRACKED ALADDIN KNOWLEDGE SYSTEMS LTD US 11/ /02/ G06F שיטה לגילוי שתוכנה מוגנת נפרצה אלדין מערכות ידע בע"מ 20/02/2008 METHOD AND APPARATUS FOR IDENTIFYING REDUNDANT SCAN ELEMENTS MARVELL ISRAEL (M.I.S.L) LTD US 60/ /02/2007 US 12/ /01/ G06F שיטה והתקן לזיהוי של אלמנטים עודפים של סריקה מארוול ישראל (אמ.איי.אס.אל) בע"מ 20/02/2008 SYSTEM AND METHOD FOR SELF- VERIFICATION OF SAFE STORAGE WITHIN HERMETICALLY SEALED CONTAINERS GRAINPRO, INC. US 11/ /02/ B65D מערכת ושיטה לאימות עצמית של אחסון ביטוחי בתוך מיכלים אטומים הרמטיים 20/02/2008 METHOD AND SYSTEM FOR RECOGNITION AND SPOTTING STOLEN CARS, VEHICLES ARE MOVING AS OPPOSED TO THE LEW, PROOF EVIDENCE SUPPLY OF TRANSGRESSION MAKING AND GIVING ABILITY OF IMMEDIATE ENFORCEMENT GUY WOLF G08B שיטה ומערכת לזיהוי ואיתור מכוניות גנובות ומכוניות הנעות בדרכים בניגוד לחוק, אספקת ראיות והוכחות לביצוע העבירות ומתן יכולת אכיפה מיידית גיא וולף 2513

12 21/02/2008 "THE KEEPER" NISIM TURGEMAN B65B "השומר" ניסים תורג'מן 21/02/2008 COFFEE MAKER ARGO LTD A47J התקן להכנת קפה ארגו בע"מ 21/02/2008 COMMUNICATION SYSTEM, TERMINATING APPARATUS, AND PON VIRTUALIZATION METHOD FOR USE THEREIN NEC CORPORATION JP 14/03/ G06F מערכת תקשורת, התקן סיום, ושיטות וירטואליזצית PON לשימוש בה 21/02/2008 DEVICE FOR MAKING GLASS, BOWEL OR HOLDER FOR CANDLE MADE OF ICE TAMAR GARMIZO A47J מיתקן להכנת כוס, קערית או מחזיק לנר מקרח תמר גרמיזו 21/02/2008 WORD ISOLATING EDUCATIONAL TOOL DWIGHT J. LOCKETT G09B כלי חינוכי לבידוד מילים 2514

13 21/02/2008 A METHOD AND SYSTEM FOR DETECTING AND BLOCKING PHISHING ATTACKS POSTALGUARD LTD H04K שיטה ומערכת לאיתור וחסימה של התקפת פישינג פוסטלגארד בע"מ 21/02/2008 PROCESS OF MAKING COMPOSITE MEMBRANES BASED ON ALUMINUM FOR MICRO FILTRATION C-FILTERS LTD B01D תהליך לייצור ממברנות מרוכבות למיקרו סינון המבוססות על אלומיניום סי פילטרס בע"מ 21/02/ SECURE INTERNET E-COMMERCE P.C.S.M. LTD. US 60/ /08/2005 WO IL2006/ /08/2006 G06Q מערכת אינטרנט בטוח למסחר אלקטרוני פי.סי.אס.אמ. בע"מ 24/02/2008 DIGITAL ASSETS INTERNET TIMELINE AGGREGATION AND SHARING PLATFORM ALLOFME LTD H04N ליקוט נכסים דיגיטליים של קו הזמן באינטרנט ופלטפורמה משותפת אול אוף מי בע"מ 24/02/2008 A METHOD AND APPARATUS FOR FORWARDING MEDIA OBJECTS TO A CELLULAR TELEPHONE USER PAPERLNX LTD H04M שיטה ומכשיר לשליחת אוביקטיי מדיה למשתמש טלפון סלולרי פייפרלנקס בע"מ 2515

14 24/02/2008 HANDLING MANIPULATOR ASSEMBLY EROWA AG CH 00587/07 10/04/ G06F טיפול במניפולטורים שלשפת סף 25/02/2008 APPARATUS AND METHOD FOR USING A MOBILE TELEPHONE UNIT AS A STANDARD LAND LINE TELEPHONE UNIT FOR AN EXISTING WIRED TELEPHONE LAND LINE ZVI HAY BEN-YISHAY H04Q מנגנון ושיטה לשימוש בטלפון נייד כמכשיר טלפון קווי סטנדרטי על גבי קו טלפון חוטי קיים שי ששון 25/02/ METHOD SYSTEM AND DEVICE FOR A FIRST AID CONTAINER UZI EZRA HAVOSHA US /02/2007 A47K שיטה מערכת ומתקן לקופסת עזרה ראשונה עוזי חבושה, עו"ד 25/08/2006 MODIFIED ANTIGEN BINDING MOLECULES WITH ALTERED CELL SIGNALING ACTIVITY GLYCART BIOTECHNOLOGY AG US 60/ /08/2005 PCT/IB/2006/ WO/2007/ C07K מולקולות קושרות אנטיגן מותאמות עם פעילות איתות תאי שונה 2516

15 25/02/2008 A BUFFER SYSTEM FOR A LONG- LASTING PRECAST ELECTROPHORESIS GEL GENE BIO-APPLICATION LTD G01N מערכת בופר לג'ל יצוק מראש לאלקטרופורזה עמיד לטווח ארוך גן יישומים בביולוגיה בע"מ 25/02/2008 ANTI-EFFRACTION SAFETY SYSTEM FOR DOOR AND WINDOW FRAMES SAVIO S.P.A. IT TO2007A /11/ G08B מערכת בטיחות נגד פריצות עבור דלת ומסגרות של חלונות 26/02/2008 HYDRAULIC WIND FARMS FOR GRID ELECTRICITY AND DESLINATION AVI EFRATY F03D חוות רוח הידראוליות לחשמל רשת ולהתפלה אבי אפרתי 26/02/ DEVICE FOR LABELING CONTENT OF CONTAINERS DROR ELI B67D התקן לסימון תכולה, לכלי קיבול דרור אלי 26/02/ A47B SLIDE-IN FOLDER FOR RING BINDER תיקיה הניתנת להשחלה לקלסר טבעות ODED GOLAN עודד גולן US 60/ /02/

16 27/02/2008 ARMORED MODULES TEXAR TECHNOLOGIES LTD B32B מדולות משוריינות טקסר טכנולוגיות בע"מ 27/02/2008 NON-LEAKING FOLDABLE POLYGONAL CONTAINER ELI LEVIS B65D מיכל מצולע מתקפל חסין בפני נזילות אלי לויס 27/02/2008 SYSTEM AND METHOD FOR OPTIMIZING HEAD-UP DISPLAY UNIFORMITY HONEYWELL INTERNATIONAL INC. US 11/ /02/ G06K מערכת ושיטה לייעול אחידות תצוגה של אלמנטים גרפיים בממשק משתמש 28/02/2008 A METHOD AND AN APPARATUS FOR ALLOWING BROWSING USERS TO COMMUNICATE WITH ONE ANOTHER OVER A COMPUTER NETWORK TWOJUMPS CORP. US 60/ /03/ G06F שיטה ומכשיר לאפשר למשתמשי רשת מחשב לתקשר ביניהם באמצעות הרשת 28/02/2008 WATER JUG ACCESSORY AND METHOD OF MITIGATING TAMPERING WITH A WATER JUG ADRIEN HADDAD A47J אביזר לקנקן מים ושיטה למניעת חדירה לקנקן אדריאן חדד 2518

17 28/02/ TURBO DECODER MARVELL ISRAEL (MISL) LTD. US 60/ /03/2007 US 12/ /02/2008 H03M מפענח טורבו מרבל ישראל MISL) ( בע"מ 28/02/2008 SYSTEM AND METHOD FOR PREMISES MONITORING USING WEIGHT DETECTION OPTIMAL INNOVATIONS, INC. US 11/ /03/ G08B מערכת ושיטה לבקרת איזורים על ידי שימוש בגלאי משקל 28/02/2008 LIGHT SWITCH USED AS A COMMUNICATION DEVICE OPTIMAL INNOVATIONS, INC. US 11/ /03/ H04M מתג אור המשמש כמכשיר תקשורת 28/02/2008 SYSTEMS AND METHODS FOR LINKING UTILITY CONTROL DEVICES OPTIMAL INNOVATIONS, INC. US 11/ /03/ H04M שיטות ומערכות לחיבור מכשירי שליטה 28/02/2008 ANTICIPATORY UTILITY CONTROL DEVICE OPTIMAL INNOVATIONS, INC. US 11/ /03/ H04M התקן לשליטה במכשיר מנבא 2519

18 28/02/2008 SYSTEMS AND METHODS FOR INFRASTRUCTURE REPORTING OPTIMAL INNOVATIONS, INC. US 11/ /03/ G08B מערכות ושיטות לדיווחי תשתית 28/02/2008 ANTICIPATORY UTILITY CONTROL DEVICE OPTIMAL INNOVATIONS, INC. US 11/ /03/ G09F התקן לשליטה במכשיר מנבא 02/03/2008 HOT GREETIUGS PILLOW HAMAMIT LTD G09F לב ברכה שמחממת את הלב חממית מן הטבע בע"מ 02/03/2008 NAPKIN RING AND SAIT AND PEPPER DISPENSER ORON MARKUS A47J מחזיק מפיות ומלחיה אורון מרקוס 02/03/2008 A METHOD FOR DIGITALLY SIGNING AN MESSAGE POSTALGUARD LTD H04L שיטה לחתימה דיגיטאלית של דבר דואר אלקטרוני פוסטלגארד בע"מ 03/03/2008 VENEER CONTAINER TZUR ADAR B65D מיכלים מפורניר צור אדר 2520

19 03/03/2008 BOOK STAND ELI NEUMAN A47F מתקן קריאה לספרים אלי ניומן 03/03/2008 COMMUNICATION DEVICE, COMMUNICATION CONTROL SYSTEM, COMMUNICATION CONTROL METHOD AND RECORDING MEDIUM RECORDING COMMUNICATION CONTROL PROGRAM NEC CORPORATION JP 26/03/ H04M התקן תקשורת, מערכת בקרת תקשורת, שיטה לבקרת תקשורת ותווך הקלטה, ותוכנית להקלטת בקרת תקשורת 03/03/2008 INDEXABLE INSERT AND DRILL USING THE SAME SUMITOMO ELECTRIC HARDMETAL CORP JP 07/03/ B23C שימת הניתן לסימון ומקדח המתשמש בו 03/03/ FINANCIAL AUTHORIZATION APPARATUS C.O.D. RAMI COMMUNICATION LTD G07B מכשיר לאישור כספי ק.ו.ד. רמי תקשורת בע"מ 04/03/ E04H PERSONAL ARTIFLICIAL SHELTER THAT SURROUNDS THE PERSON(S). מחסה אישי/קבוצתי מלאכותי ניד המקיף, את האדם/אנשים. DR. HAIM AMRAM BEN-SIMHON ד"ר חיים עמרם בן שמחון 2521

20 04/03/2008 ARM WATER CARRIER SARIT COHEN A47K מתקן מים זרועי שרית כהן 04/03/2008 INSERT FOR STABILIZING MEN'S HATS YOSEF FARCKASH A47D תותב מייצב צורת כובע של גבר יוסף פרקש 04/03/ H04L A MULTI-LEVEL MULTI-PIN DIFFERENTIAL INTERFACE ממשק דיפרנציאלי רב שלבים רב שבבים MARVELL ISRAEL (MISL) LTD. מרבל ישראל MISL) ( בע"מ US 60/ /03/ /03/2008 DIGITAL RANDOM NUMBER GENERATOR BASED ON DIGITALLY- CONTROLLED OSCILLATORS SANDISK IL LTD G06F מחולל מספרים אקראיים ספרתי המבוסס על מתנדים נשלטים ספרתית סנדיסק אייאל בע"מ 04/03/2008 NON-LEAKING FOLDABLE POLYGONAL CONTAINER ELI LEVIS B67C מיכל מצולע מתקפל חסין בפני נזילות אלי לויס 2522

21 28/11/2006 IL-21 ANTAGONISTS ZYMOGENETICS INC. US 60/ PCT/US/2006/ WO/2007/ /11/ C07K אנטגוניסטים IL 21 05/03/2008 DEVICE, SYSTEM, AND METHOD OF ELECTRONIC COMMUNICATION UTILIZING AUDIOVISUAL CLIPS MY HOLLYWOOD LTD. US 60/ /03/ H04M מכשיר, מערכת ושיטה לתקשורת אלקטרונית באמצעות קליפים אודיו ויזואלים 06/03/2008 A METHOD OF MANUFACTURING A CERAMIC CUTTING INSERT SANDVIK INTELLECTUAL PROPERTY AB SE /03/ B23P שיטה ליצור תותבת חיתוך קרמית 26/09/2006 COMBINED VENTILATOR INEXSUFFLATOR INNOVENT MEDICAL SOLUTIONS, INC. US 60/ /09/2005 US 60/ /07/2006 PCT/IB/2006/ WO/2007/ A61M התקן המסייע לנשימה המשולב עם מאוורר 2523

22 15/09/2006 FLEXIBLE ADVERTISING SYSTEM WHICH ALLOWS ADVERTISERS WITH DIFFERENT VALUE PROPOSITIONS TO EXPRESS SUCH VALUE PROPOSITIONS TO THE ADVERTISING SYSTEM GOOGLE, INC. US 11/ /09/2005 PCT/US/2006/ WO/2007/ G09F מערכת פרסום גמישה המאפשרת למפרסמים בעלי הנחות עריכות שונות לבטא הנחות ערכיות כאלה במערכת הפרסום 27/09/2006 MODULATION OF TLR-MEDIATED IMMUNE RESPONSES USING ADAPTOR OLIGONUCLEOTIDES COLEY PHARMACEUTICAL GROUP, INC. US 60/ /09/2005 PCT/US/2006/ WO/2007/ A61K אפנון של תגובות אימוניות מתווכות TLR תוך שימוש במתאם אוליגונוקלאוטידים 26/09/2006 PDGF AMPHIPHILIC POLYMER COMPLEX ADOCIA FR 05/ /09/2005 PCT/IB/2006/ WO/2007/ A61K קומפלס אמפיפילי של פולימר PDGF 2524

23 01/11/2006 COMPOSITIONS, REAGENTS AND KITS FOR AND METHODS OF DIAGNOSING, MONITORING AND TREATING HORMONAL IMBALANCE C07K תכשירים, מגיבים וערכות עבור ושיטה לאבחון, מעקב וטיפול בחוסר איזון הורמונלי LIAT MINTZ US 60/ PCT/US/2006/ WO/2007/ /11/2005 ליאת מינץ 20/10/2006 VERSATILE ROBOTIC CONTROL MODULE IROBOT CORPORATION US 60/ /10/2005 US 60/ /10/2005 US 60/ /03/2006 US 60/ /08/2006 PCT/US/2006/ WO/2007/ G05B מודול רב גווני לבקרה רובוטית 28/12/ NON-PLASMA METHOD OF REMOVING PHOTORESIST FROM A SUBSTRATE THE ARIZONA BOARD OF REGENTS ON BEHALF OF THE UNIVERSITY OF ARIZONA US 11/ /10/2005 PCT/US/2005/ WO/2007/ C03C שיטה להסרת חומר רגיש אור ממצע ללא שימוש בפלסמה 2525

24 27/10/2006 NOVEL INDOLE-CONTAINING BETA AGONISTS, METHOD FOR PRODUCING THEM AND THEIR USE AS DRUGS BOEHRINGER INGELHEIM INTERNATIONAL GMBH DE /10/2005 PCT/EP/2006/ WO/2007/ C07D בתא אגוניסטים חדשים המכילים אינדול, שיטה לייצורם ושימושם כתרופות 11/12/2006 ANTIBODIES AGAINST AMYLOID BETA 4 WITH GLYCOSYLATED ASN IN THE VARIABLE REGION F. HOFFMANN-LA ROCHE AG EP /12/2005 PCT/EP/2006/ WO/2007/ C07K נוגדנים נגד אמילויד בתא 4 עם Asn מותמר בגליקוציד באיזור המשתנה 19/10/2006 IMPROVED AIRFLOW DISTRIBUTION TO A LOW EMISSION COMBUSTOR POWER SYSTEMS MFG. LLC US 11/ /10/2005 PCT/US/2006/ WO/2007/ F02C חלוקה משופרת של זרם אויר לתא שריפה בעל פליטה נמוכה 26/10/2006 COUPLING HAVING ANGULARLY ORIENTED CAVITY VICTAULIC COMPANY US 60/ /10/2005 PCT/US/2006/ WO/2008/ F16L מחבר בעל חלל עם כיווניות זויתית 2526

25 14/11/2006 OXAZOLE COMPOUND AND PHARMACEUTICAL COMPOSITION OTSUKA PHARMACEUTICAL CO., LTD JP 15/11/ PCT/JP/2006/ WO/2007/ C07D תרכובת אוקסאזול ותכשיר רוקחות 30/11/2006 PURINE DERIVATIVES AND METHODS OF USE THEREOF INOTEK PHARMACEUTICALS CORPORATION US 60/ /11/2005 PCT/US/2006/ WO/2007/ A01N תולדות פורין ושיטות לשימוש בהן 09/11/2006 SILICON NANOPARTICLE PHOTOVOLTAIC DEVICES THE BOARD OF TRUSTEES OF THE UNIVERSITY OF ILLINOIS, US 60/ /11/2005 PCT/US/2006/ WO/2008/ H01L התקנים פוטוולוטאיים המבוססים על חלקיקי סיליקון זעירים 2527

26 02/11/2006 WASTEWATER TREATMENT METHOD COMPRISING DECANTATION AND FINE SCREENING STAGES AND DEVICE FOR CARRYING OUT SAID METHOD OTV SA FR /11/2005 PCT/EP/2006/ WO/2007/ C02F שיטה לטיפול במי שפכים הכוללת שפיתה ושלבי סריקה מדוקדקת והתקן לביצוע שיטה זו 08/11/2006 THERAPEUTIC VACCINES TARGETING HMGB1 PHARMEXA A/S DK PA US 60/ PCT/DK/2006/ WO/2007/ C07K חיסונים רפואיים הממוענים ל HMGB1 09/11/ /11/ /11/2006 LIQUID CONTAINER AND LIQUID FILLING METHOD SEIKO EPSON CORPORATION JP /11/2005 JP /11/2005 JP /12/2005 JP /08/2006 PCT/JP/2006/ WO/2007/ B41J מיכל לנוזלים ושיטה למילוי נוזלים 2528

27 25/10/ (HETERO) ARYL COMPOUNDS WITH MCH ANTAGONISTIC ACTIVITY AND MEDICAMENTS COMPRISING THESE COMPOUNDS BOEHRINGER INGELHEIM INTERNATIONAL GMBH EP /10/2005 PCT/EP/2006/ WO/2007/ C07D תרכובות (הטרו) אריל בעלות פעילות אנטגוניסטית ל MCH ותרופות המכילות תרכובות אלו 24/10/2006 PIPERIDIN-4-YL-PYRIDAZIN-3- YLAMINE DERIVATIVES AS FAST DISSOCIATING DOPAMINE 2 RECEPTOR ANTAGONISTS JANSSEN PHARMACEUTICA N.V. EP /10/2005 EP /01/2006 EP /02/2006 PCT/EP/2006/ WO/2007/ C07D תולדות פיפרידין 4 יל פירידאזין 3 ילאמיניות כמפרידות במהירות אנטגוניסטים של קולטן דופאמין 2 21/11/2006 CARBAMATE COMPOUNDS AS 5-HT4 RECEPTOR AGONISTS THERAVANCE, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07D תרכובות קרבאמאט כאגוניסטים של קולטן HT

28 24/10/2006 ELECTROMAGNETIC WAVE SENSOR WITH TETRAHERTZ BANDWIDTH THALES FR /10/2005 PCT/EP/2006/ WO/2007/ G01N חיישן גל אלקטרומגנטי עם רוחב פס טטרה הרצי 24/10/2006 OVULATION CYCLE MONITORING AND MANAGEMENT MANAWATU BIOTECH INVESTMENTS LTD. US 60/ /10/2005 PCT/IB/2006/ WO/2007/ G01N ניטור וניהול של מחזור ביוץ 16/10/2006 CAN FOR BEVERAGES COMPRISING A PROTECTIVE LID JULIEN SAVINO OF FR /10/2005 FR /03/2006 FR /03/2006 PCT/FR/2006/ WO/2007/ B65D פחית עבור משקאות המכילה מכסה מגן 09/10/2006 METHOD FOR MODIFYING INSULATING OR SEMI-CONDUCTIVE SURFACES, AND RESULTING PRODUCTS ALCHIMER FR /10/2005 PCT/FR/2006/ WO/2007/ C08J שיטה לשינוי משטחים מבודדים או מוליכים למחצה והתוצרים המתקבלים 2530

29 02/10/2006 METHOD FOR TREATING/CONTROLLING/KILLING FUNGI AND BACTERIA STAVAL PHARMA, LTD. US 60/ /10/2005 PCT/US/2006/ WO/2007/ A01N שיטה לטיפול/בקרה/קטילה של פטריות ובקטריות 06/11/ (BENZIMIDAZOL-1-YL)-N-(4- PHENYLTHIAZOL-2-YL)ACETAMIDE DERIVATIVES USEFUL IN TREATMENT OF TRPV1 RELATED DISORDERS N.V. ORGANON EP /11/2005 PCT/EP/2006/ WO/2007/ C07D תולדות 2 (בנזימידאזול 1 יל) N (4 פנילתיזול 2 יל)אצטאמידיות המשמשות לטיפול באי סדרים הקשורים ל TRPV1 10/11/2006 PROCESS FOR THE PREPARATION OF OLANZAPINE EGIS GYOGYSZERGYAR Nyilvanosan Mukodo Reszvenytarsasag HU P /11/2005 PCT/HU/2006/ WO/2007/ C07D תהליך להכנת אולאנזאפין 2531

30 02/11/2006 BIOCIDAL STRUCTURAL BARRIER (BSB) SEP INNOVATERM, FR /11/2005 FR /08/2006 PCT/EP/2006/ WO/2007/ C04B חסמים מבניים של חומרים קוטלי יצורים חיים 06/11/2006 FUNGICIDAL MIXTURES BASF SE US 60/ PCT/EP/2006/ WO/2007/ /11/ A01N תערובות קוטלות פטריות 06/11/2006 NOVEL PYRROLIDINE DERIVATIVES AS INHIBITORS OF COAGULATION FACTOR XA F. HOFFMANN-LA ROCHE AG EP /11/2005 PCT/EP/2006/ WO/2007/ C07D תולדות פירולידיניות חדשות כמעכבות פקטור הקרשה XA 03/11/2006 PROCESS FOR THE PREPARATION OF A LEUKOTRIENE ANTAGONIST AND INTERMEDIATES THEREOF ESTEVE QUIMICA, S.A. EP /11/2005 US 60/ /11/2005 PCT/EP/2006/ WO/2007/ C07D תהליך להכנת אנטגוניסט של לוקוטריאן וחומרי ביניים עבורו 2532

31 01/11/2006 USES OF ANTI-CD40 ANTIBODIES XOMA TECHNOLOGY LTD. US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61K שימושים בנוגדנים אנטי CD40 24/10/2006 APPARATUS AND METHOD FOR MEASURING BIOLOGIC PARAMETERS MARCIO MARC ABREU US 60/ /10/2005 US 60/ /05/2006 PCT/US/2006/ WO/2007/ A61B התקן ושיטה למדידה של נתונים ביולוגיים 02/08/2006 A HYDROPHILIC POLYMER SPONGE HEMCON, INC. US 11/ /10/2005 PCT/US/2006/ WO/2007/ A61F ספוג מפולימר הידרופילי 23/10/2006 ANTIBODIES WITH ENHANCED ANTIBODY-DEPENDENT CELLULAR CYTOXICITY ACTIVITY, METHODS OF THEIR PRODUCTION AND USE GTC BIOTHERAPEUTICS, INC. US 60/ /10/2005 PCT/US/2006/ WO/2007/ C07K נוגדנים עם פעילות ציטוטקסית תאית תלוית נוגדן מוגברת, שיטות להפקתם ולשימוש בהם 2533

32 27/10/2006 RESOURCE ALLOCATION FOR SHARED SIGNALING CHANNELS IN OFDM QUALCOMM INCORPORATED US 11/ /10/2005 US 11/ /03/2006 PCT/US/2006/ WO/2007/ H04Q אמצעי מינון לערוצי שידור משותפים ב OFDM 26/10/2006 A METHOD AND APPARATUS FOR PRE-CODING FREQUENCY DIVISION DUPLEXING SYSTEM QUALCOMM INCORPORATED US 11/ /10/2005 PCT/US/2006/ WO/2007/ H04B שיטה והתקן עבור מערכת כפולת תדר קדם קידודי 27/10/2006 SEAMLESS INTER-FREQUENCY HANDOFF IN WIRELESS COMMUNICATION NETWORKS QUALCOMM INCORPORATED US 11/ /10/2005 PCT/US/2006/ WO/2007/ H04Q מעבר בין תדרי בין רשתות תקשורת אלחוטיות ללא תפר 2534

33 20/10/2006 VIDEO ERROR CONTROL BASED ON REVERSE LINK INFORMATION QUALCOMM INCORPORATED US 60/ /10/2005 US 11/ /12/2005 US 11/ /06/2006 PCT/US/2006/ WO/2007/ H04N בקרת שגיאת וידאו מבוססת על קישור מידע מהופך 27/10/2006 PRECODING FOR SEGMENT SENSITIVE SCHEDULING IN WIRELESS COMMUNICATION SYSTEMS QUALCOMM INCORPORATED US 60/ /10/2005 PCT/US/2006/ WO/2007/ H04L קידוד מקדים למקטע רגיש לתזמון ברשתות תקשורת אלחוטיות 26/10/2006 PILOT SYMBOL TRANSMISSION IN WIRELESS COMMUNICATION SYSTEMS QUALCOMM INCORPORATED US 60/ /10/2005 US 11/ /08/2006 PCT/US/2006/ WO/2007/ H04J שידור סמל ניסיוני במערכות תקשורת אלחוטיות 2535

34 20/10/2006 POINTER COMPUTATION METHOD AND SYSTEM FOR A SCALABLE, PROGRAMMABLE CIRCULAR BUFFER QUALCOMM INCORPORATED US 11/ /10/2005 PCT/US/2006/ WO/2007/ G06F שיטה לחישוב מחוון ומערכת למקום לאכסון זמני בזיכרון מדיד, בר תכנות מעגלי 20/10/2006 METHOD AND SYSTEM FOR ADAPTIVE ENCODING OF REAL- TIME INFORMATION IN WIRELESS NETWORKS QUALCOMM INCORPORATED US 60/ /10/2005 US 11/ /12/2005 PCT/US/2006/ WO/2007/ H04N שיטה ומערכת לקידוד מתואם לאנפורמצייה בזמן אמת ברשתות אלחוטיות 20/10/2006 BACKGROUND THREAD PROCESSING IN A MULTITHREAD DIGITAL SIGNAL PROCESSOR QUALCOMM INCORPORATED US 11/ /10/2005 PCT/US/2006/ WO/2007/ G06F עיבוד ביצוע ברקע מעבד אות דיגיטלי רב ביצועים בהליך 2536

35 10/11/2006 METHOD FOR DIAGNOSTICATING HEPATIC DISEASES AND FOR SCREENING MOLECULES FOR TREATING SAID DISEASES SANOFI-AVENTIS FR /11/2005 PCT/FR/2006/ WO/2007/ G01N שיטה לאבחון של מחלות כבד ולסריקה של מולקולות לטיפול במחלות אלה 27/10/2006 HETEROCYCLIC AMIDE COMPOUND AND USE THEREOF TAKEDA PHARMACEUTICAL COMPANY LIMITED JP 28/10/ PCT/JP/2006/ WO/2007/ C07D תרכובת אמיד הטרוציקלית ושימושיה 09/11/2006 DECREASING OR PREVENTING SUB- SURFACE GEOLOGICAL MATTER CONTAMINATION BY AGROCHEMICALS YEDA RESEARCH AND DEVELOPMENT CO. LTD US 60/ /11/2005 US 60/ /12/2005 PCT/IL/2006/ WO/2007/ A01N הפחתת או מניעת זיהום של אגרוכימיקלים בחומר גיאולוגי תת קרקעי ידע חברה למחקר ופיתוח בע"מ 2537

36 25/10/2005 CHESS PLAYING METHOD AND DEVICE FOR CARRYING OUT SAID METHOD VYACHESLAV ALEKSANDROVICH FETISOV A63F שיטה למשחק בשח ומכשיר לביצועה PCT/RU/2005/ WO/2007/ /10/2006 METHODS FOR CHLORINATING SUCROSE-6-ESTER HEALTHY BRANDS, LLC US 60/ /10/2005 US 11/ /10/2006 PCT/US/2006/ WO/2007/ C08K שיטות להפיכה לכלור של סוקרוז 6 אסטר 04/01/2007 TREATMENT OF STRESSED PATIENTS NESTEC S.A. US 60/ /01/2006 PCT/EP/2007/ WO/2007/ A23L טיפול בחולים תחת לחץ 27/09/2006 APPLIANCE FOR LOWERING AND TRACKING AN UNDERWATER VESSEL ATLAS ELEKTRONIK GMBH DE /12/2005 PCT/EP/2006/ WO/2007/ B63G מכשיר להורדה ועקיבה אחרי כלי שייט תת ימי 2538

37 10/11/2005 DEVICE FOR DETERMINING THE GLUCOSE LEVEL IN BODY TISSUE SOLIANIS HOLDING AG PCT/CH/2005/ WO/2007/ A61B מכשיר לקביעת רמת הסוכר ברקמת גוף 03/11/2006 A CONCENTRATE DERIVED FROM A MILK PRODUCT ENRICHED IN NATURALLY OCCURRING SIALYLLACTOSE AND PROCESS FOR PREPARATION THEREOF ARLA FOODS AMBA US 60/ /11/2005 PCT/DK/2006/ WO/2007/ A23C תרכיז הנגזר ממוצר חלבי המועשר בסיאליללקטוז טבעי ותהליך להכנתו 02/11/2006 EXTRACTING DEVICE FOR SURGICAL FASTENERS ENDOGUN MEDICAL SYSTEMS LTD. US 60/ /11/2005 PCT/IL/2006/ WO/2007/ A61B התקן שליפה עבור מהדקים כירורגיים אנדוגן מערכות רפואיות בע"מ 20/07/2006 MOVABLE PULLEY HEADS FOR A LATERAL SPREADER MOVEMENT MAERSK ESPANA S.A. ES P /11/2005 PCT/ES/2006/ WO/2007/ B66C ראשי גלגלת ניידים עבור תנועה צדדית של מפזר 2539

38 19/12/2006 USE OF CO-GRINDING AGENTS IN A METHOD FOR PRODUCING NATURAL CALCIUM CARBONATES, OBTAINED CO-GROUND PRECIPITATIONS, SUSPENSIONS AND DRY PIGMENTS AND THE USE THEREOF COATEX S.A.S. FR /12/2005 PCT/IB/2006/ WO/2007/ C09C שיטה לשימוש בגורמי עזר טחינה בשיטה ליצור קלציום קרבונאט טבעי המתקבל ממשקעים שעברו טחינת עזר, סוספנסיות ופיגמנטים ושימוש בהם 02/06/2006 WIPER FOR USE WITH DISINFECTANTS KIMBERLY-CLARK WORLDWIDE, INC. US 11/ /12/2005 PCT/US/2006/ WO/2007/ C11D מגב לשימוש עם מחטאים 28/11/2006 PRECURSOR COMPOUND OF RADIOACTIVE HALOGEN LABELED ORGANIC COMPOUND NIHON MEDI-PHYSICS CO., LTD JP 29/11/ PCT/JP/2006/ WO/2007/ C07C תרכובת פרקרסורית של תרכובת אורגנית המתוייגת עם הלוגן רדיואקטיבי 2540

39 08/12/2006 PROCESS FOR THE PREPARATION OF A PHARMACEUTICAL INTERMEDIATE EGIS GYOGYSZERGYAR Nyilvanosan Mukodo Reszvenytarsasag HU P /12/2005 PCT/HU/2006/ WO/2007/ C07D תהליך להכנת חומר ביניים רוקחי 08/12/2006 OPTICALLY ACTIVE CARBAMATES, PROCESS FOR PREPARATION THEREOF AND USE THEREOF AS PHARMACEUTICAL INTERMEDIATES EGIS GYOGYSZERGYAR Nyilvanosan Mukodo Reszvenytarsasag HU P /12/2005 PCT/HU/2006/ WO/2007/ C07D קרבאמאטים פעילים אופטית, תהליך להכנתם ושימוש בהם כחומר ביניים רוקחי 02/11/2006 REINFORCEMENT FOR CONCRETE ELEMENTS AND SYSTEM AND METHOD FOR PRODUCING REINFORCED CONCRETE ELEMENTS BBA BLACKBULL AS NO /11/2005 PCT/NO/2006/ WO/2007/ E04C חיזוק לאלמנטים מביטון ומערכת ושיטה ליצור אלמנטים מביטון מחוזקים 2541

40 13/11/2006 INDOLE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PHARMA MAR, S.A. GB /11/2005 PCT/GB/2006/ WO/2007/ C07D תולדות אינדול ותכשירי רוקחות המכילים אותן 02/11/2006 sirna MOLECULES AND USE THEREOF TO PREPARE PHARMACEUTICAL COMPOSITIONS PROTIVA BIOTHERAPEUTICS, INC. US 60/ /11/2005 US 60/ /06/2006 PCT/CA/2006/ WO/2007/ C07H מולקולות sirna ושימוש בהן להכנת תכשירי רוקחות 03/11/2006 QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME PORTOLA PHARMACEUTICALS, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07D תולדות קווינאזולין ותכשירי רוקחות במכילים אותן 2542

41 03/11/2005 METHOD OF SOLIDIFYING SUGAR SOLUTIONS OBTAINED FROM GRAPES AND FROM MUST APPLIED PROCESSES, CONCENTRATED RECTIFIED MUST, CONCENTRATED RECTIFIED JUICE AND TRANSFORMATION PRODUCTS OF VEGETABLE ORIGIN AND THEIR DERIVATIVES PIRRONE, LUIGI PCT/IT/2005/ WO/2007/ C12G שיטה לגיבוש תמיסות סוכר המתקבלות מתהליכי הפקת מיצים מענבים, מיץ פירות מרוכז ומזוקק וטרנספורמציה של מוצרים ממקור צמחי ונגזרותיהם 20/11/2006 PYRIDO-,PYRAZO-AND PYRIMIDO- PYRIMIDINE DERIVATIVES AS mtor INHIBITORS KUDOS PHARMACEUTICALS LIMITED US 60/ /11/2005 GB /11/2005 US 60/ /08/2006 US 60/ /08/2006 PCT/GB/2006/ WO/2007/ C07D נגזרות פירידו,פיראזו ופירימידו פירימידין כמעכבי mtor 02/11/2006 HUMAN GROWTH HORMONE PATCH FORMULATIONS TRANSPHARMA MEDICAL LTD. US 60/ /11/2005 US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61K פורמולציות לרטיות של הורמון גדילה של אדם טרנספארמה מדיקל בע"מ 2543

42 01/11/2006 COMPOSITIONS AND METHODS FOR CELL KILLING SURE INTERNATIONAL VENTURES B.V. US 60/ /11/2005 PCT/IL/2006/ WO/2007/ A01N הרכבים ושיטה להריגת תאים שור אינטרנשיונל ונטשר 23/10/2006 CATION-EXCHANGE DISPLACEMENT CHROMATOGRAPHY PROCESS AND CATIONIC ORGANIC COMPOUNDS FOR USE AS DISPLACER COMPOUNDS IN CATION- EXCHANGE DISPLACEMENT CHROMATOGRAPHY PROCESS SACHEM INC. US 11/ /11/2005 PCT/US/2006/ WO/2007/ G01N שיטה לכרומטוגרפיה באמצעות חומרים אורגניים קטיוניים 08/11/2006 PROCESS FOR PREPARATION OF (3R,5R)-7-[2-(4-FLUOROPHENYL)-5- ISOPROPYL-3-PHENYL-4-[(4-HYDROXY METHYL PHENYL AMINO)CARBONYL]-PYRROL-1-YL]- 3,5-DIHYDROXY-HEPTANOIC ACID HEMI CALCIUM SALT RANBAXY LABORATORIES LIMITED IN 2964/DEL/ /11/2005 IN DEL/2005/ /11/2005 IN DEL/2005/ /11/2005 PCT/IB/2006/ WO/2007/ C07D תהליך להכנת מלח המי קלציום של ( R3 R5) 7 [2 (4 פלואורופניל) 5 איזופרופיל 3 פניל 4)] 4 הידרוקסי מתיל פניל אמינו) קרבוניל] פירול 1 איל] 3, 5 דיהידרוקסי חומצה הפטונאית 2544

43 07/11/2006 PROCESS FOR (3R,5R)-7-[2-(4- FLUOROPHENYL)-5-ISOPROPYL-3- PHENYL-4-[(4-HYDROXY METHYL PHENYL AMINO) CARBONYL]- PYRROL-1-YL]-3,5-DIHYDROXY- HEPTANOIC ACID HEMI CALCIUM SALT RANBAXY LABORATORIES LIMITED IN 2964/DEL/ /11/2005 IN DEL/2005/ /11/2005 IN DEL/2005/ /11/2005 PCT/IB/2006/ WO/2007/ C07D תהליך לייצור מלח המי קלציום של ( R3,R5) 7 [2 (4 פלואורופניל) 5 איזופרופיל 3 פניל 4)] 4 הידרוקסי מתיל פניל אמינו) קרבוניל] פירול 1 איל] 3, 5 דיהידרוקסי חומצה הפטנואית 07/11/2006 COMBINATION GRIP FOR AN EXERCISE DEVICE FITNESS ANYWHERE, INC US 60/ /11/2005 US 11/ /11/2006 PCT/US/2006/ WO/2007/ A63B ידית משולבת למתקן התעלמות 13/11/2006 ANTI-PROLIFERATIVE COMBINATION THERAPY COMPRISING A PLATINUM-BASED CHEMOTHERAPEUTIC AGENT AND EGFR INHIBITORS OR PYRIMIDINE ANALOGUES GPC BIOTECH AG EP /11/2005 PCT/EP/2006/ WO/2007/ A61K טיפול משולב נוגד פרוליפירציה הכולל תכשיר כימותרפי מבוסס פלטינה ומעכבי EGFR או אנלוגים פירימידינים 2545

44 23/11/2006 F,G,H,I AND K CRYSTAL FORMS OF IMATINIB MESYLATE NOVARTIS AG GB /11/2005 GB /11/2005 US 60/ /11/2005 US 60/ /11/2005 US 60/ /11/2005 PCT/EP/2006/ WO/2007/ של אימאטיניב C07D צורות גביש F,G,H,I ו K מזילאט 08/11/2006 AZAINDOLE-2-CARBOXAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG EP /11/2005 PCT/EP/2006/ WO/2007/ C07D תולדות אזאינדול 2 קרבוקסאמיד 03/11/2006 CONTINUOUSLY SEALING ONE WAY VALVE ASSEMBLY AND FLUID DELIVERY SYSTEM FORMULATIONS FOR USE THEREIN RESEAL INTERNATIONAL LIMITED PARTNERSHIP US 11/ /11/2005 US 60/ /08/2006 PCT/US/2006/ WO/2007/ B65D הרכבת שסתום חד כיוונית רצופת איטום ומערכת לחלוקת פורמולת נוזל לשימוש בהן 2546

45 03/11/2006 ONE WAY VALVE ASSEMBLY RESEAL INTERNATIONAL LIMITED PARTNERSHIP US 11/ /11/2005 US 60/ /03/2006 US 60/ /03/2006 US 60/ /08/2006 PCT/US/2006/ WO/2007/ B65D הרכבת שסתום חד כיוונית 24/10/2006 ONE WAY VALVE ASSEMBLY RESEAL INTERNATIONAL LIMITED PARTNERSHIP US 11/ /11/2005 PCT/US/2006/ WO/2007/ B65D הרכבת שסתום חד כיוונית 21/11/2006 SUBSTITUTED BICYCLIC PYRIMIDONE DERIVATIVES SANOFI-AVENTIS EP /11/2005 PCT/IB/2006/ WO/2007/ C07D נגזרות מותמרות ביציקליות של פירימידון 2547

46 22/11/2006 ISOQUINOLINE AND BENZO[H]ISOQUINOLINE DERIVATIVES, PREPARATION AND THERAPEUTIC USE THEREOF AS ANTAGONISTS OF HISTAMINE H3 RECEPTOR SANOFI-AVENTIS EP /11/2005 PCT/EP/2006/ WO/2007/ C07D נגזרות של איזוקוינולין ובנזו( H )איזוקוינולין, הכנה ושימוש רפואי שלהם כאנטגוניסטים של רצפטור H3 היסטמין 17/11/2006 INHIBITORS OF DIACYGLYCEROL ACYLTRANSFERASE (DGAT) F. HOFFMANN-LA ROCHE AG US 60/ /11/2005 US 60/ /10/2006 PCT/EP/2006/ WO/2007/ C07D מעכבים של דיאצילגליצרול אצילטרנספראז (DGAT) 03/11/2006 FABRIC SUPPORT FRAME SECTION NEWMAT S.A. FR /11/2005 PCT/FR/2006/ WO/2007/ E04B מקטע מסגרת לתמיכה בבד 05/12/2006 ANTI-IL -17 ANTIBODIES ELI LILLY AND COMPANY US 60/ /12/2005 US 60/ /05/2006 PCT/US/2006/ WO/2007/ C07K נוגדנים כנגד IL

47 14/11/2006 BIOMARKERS FOR ANTI-NOGO-A ANTIBODY TREATMENT IN SPINAL CORD INJURY UNIVERSITY OF ZURICH US 60/ /11/2005 PCT/EP/2006/ WO/2007/ G01N סמנים ביולוגיים לטיפול עם נוגדן כנגד A NOGO בפגיעות בחוט השידרה 27/10/2006 MORPHOLINE TYPE CINNAMIDE COMPOUND EISAI R&D MANAGEMENT CO., LTD JP 24/11/ JP /07/2006 PCT/JP/2006/ WO/2007/ C07D תרכובת סינאמיד מסוג מורפולין 20/11/2006 NOVEL 2-AMINO-IMIDAZOLE-4-ONE COMPOUNDS AND THEIR USE IN THE MANUFACTURE OF A MEDICAMENT TO BE USED IN THE TREATMENT OF COGNITIVE IMPAIRMENT, ALZHEIMER'S DISEASE, NEURODEGENERATION AND DEMENTIA ASTRAZENECA AB US 60/ /11/2005 US 60/ /06/2006 PCT/SE/2006/ WO/2007/ C07D תרכובות חדשות של 2 אמינו אימידאזול 4 און ושימושן בייצור תרופה לשימוש בטיפול בליקוי קוגניטיבי, מחלת אלצהיימר, נוירודגנרציה ודימנציה 2549

48 01/11/2006 BIODEGRABLE COMPOSITE FOR INTERNAL LOCAL RADIOTHERAPY YISSUM RESEARCH DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF JERUSALEM US 60/ /11/2005 PCT/IL/2006/ WO/2007/ A61K תכשיר מתכלה לרדיוטרפיה יישום חברה לפיתוח המחקר של האוניברסיטה העברית בירושלים 03/11/ LIPOXYGENASE-ACTIVATING PROTEIN (FLAP) INHIBITORS AMIRA PHARMACEUTICALS, INC. US 60/ /11/2005 US 60/ /05/2006 US 60/ /08/2006 PCT/US/2006/ WO/2007/ C07K מעכבי חלבון משפעל 5 ליפוקסיגנאז (FLAP) 03/11/2006 MANDREL USED FOR DIGITAL PRINTING ON CAN MEMBERS BALL PACKAGING EUROPE HOLDING GMBH & CO. KG EP /11/2005 PCT/EP/2006/ WO/2007/ B41F סרן המשמש להדפסה דיגיטלית על גבי פחיות 2550

49 13/11/2006 ASPARTIC PROTEASE INHIBITORS VITAE PHARMACEUTICALS, INC. US 60/ /11/2005 US 60/ /09/2006 US 60/ /09/2006 PCT/US/2006/ WO/2007/ C07D מעכבי אספרטיק פרוטאז 02/11/ FLEXIBLE MULTICAST AND/OR BROADCAST LISTENING INTERVALS NOKIA CORPORATION US 60/ /11/2005 PCT/IB/2006/ WO/2007/ G06F מרווחי האזנה גמישים להעברת מידע לנמענים רבים ו/או שידור 02/11/2006 MECHANISM FOR MULTICAST AND/OR BRODCAST ACKNOWLEDGEMENTS NOKIA CORPORATION US 60/ /11/2005 PCT/IB/2006/ WO/2007/ H04L מנגנון אישור העברת מידע לנמענים רבים ו/או שידור 2551

50 02/11/2006 LIQUID CONCENTRATE/EXTRACT BEVERAGE DISPENSER WITH REPLACEABLE CONCENTRATE/EXTRACT CARTRIDGE INTELLIGENT COFFEE COMPANY. L.L.C. US 11/ /11/2005 US 60/ /04/2006 US 60/ /09/2006 PCT/US/2006/ WO/2007/ B65D מנפק תרכיז/תמצית משקה נוזליים עם מיכל תרכיז/ תמצית הניתן להחלפה 27/10/2006 REAGENTS, METHODS AND SYSTEMS FOR SELECTING A CYTOTOXIC ANTIBODY OR VARIANT THEREOF THE ROCKEFELLER UNIVERSITY US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61K מגיבים, שיטות ומערכות לברירת נוגדן ציטוטוקסי או וריאנט שלו 24/10/2006 METHOD AND APPARATUS OF EXCHANGING MESSAGES VIA A WIRELESS DISTRIBUTION SYSTEM BETWEEN GROUPS OPERATING IN DIFFERENT FREQUENCIES INTERDIGITAL TECHNOLOGY CORPORATION US 60/ /11/2005 US 11/ /09/2006 PCT/US/2006/ WO/2007/ H04L שיטה ומערכת להחלפת הודעות באמצעות מערכת הפצה אלחוטית בין קבוצות הפועלות בתדירויות שונות 2552

51 08/12/2006 A BETA 1-42 SPECIFIC MONOCLONAL ANTIBODIES WITH THERAPEUTIC PROPERTIES AC IMMUNE S.A. EP /12/2005 EP /07/2006 EP /10/2006 PCT/EP/2006/ WO/2007/ A61K נוגדנים חד שבטיים בררניים לבטא 42 1 בעלי תכונות רפואיות 10/11/2006 METHOD AND APPARATUS FOR COMPUTER MODELING THE HUMAN BRAIN FOR PREDICTING DRUG EFFECTS IN SILICO BIOSCIENCES, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ G06F שיטה והתקן להדמיית המוח של בן אדם באמצעות מחשב עבור חיזוי ההשפעה של סמים 13/11/2006 QUINAZOLINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THE SAME VERTEX PHARMACEUTICALS INCORPORATED US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07D תולדות קווינאזולין ותכשירי רוקחות המכילים אותן 2553

52 01/11/ METHOD AND SYSTEM FOR PERFORMING PEER-TO-PEER COMMUNICATION BETWEEN STATIONS WITHIN A BASIC SERVICE SET INTERDIGITAL TECHNOLOGY CORPORATION US 60/ /11/2005 PCT/US/2006/ WO/2007/ H04L שיטה ומערכת לביצוע תקשורת PEER TO PEER בין תחנות בתוך מערכת שרות בסיסית 30/10/2006 METHOD AND SYSTEM FOR AUTONOMOUS CHANNEL COORDINATION FOR A WIRELESS DISTRIBUTION SYSTEM INTERDIGITAL TECHNOLOGY CORPORATION US 60/ /11/2005 PCT/US/2006/ WO/2007/ H04L שיטה ומערכת עבור קואורדינצית ערוץ אוטונומי עבור מערכת הפצה אלחוטית 21/11/2006 SKIN REPAIR ACCELERATING THERAPEUTIC AGENT CONTAINING DESACYL GHERLIN AND DERIVATIVES THEREOF AS ACTIVE AGENTS UNIVERSITY OF MIYAZAKI JP 21/11/ PCT/JP/2006/ WO/2007/ A61K חומר תרפויטי לזירוז שיקום העור המכיל דסאציל גהרלין ונגזרות שלו כחומרים פעילים 2554

53 21/11/ A61K חומר תרפויטי לזירוז שיקום העור המכיל גהרלין ונגזרות שלו או חומר הפועל על RLa GHS כמרכיב פעיל 03/11/2006 SEMI-AUTOMATIC MULTIPLEXING SYSTEM FOR AUTOMATED SEMICONDUCTOR WAFER TESTING QUALITAU, INC. US 11/ /11/2005 PCT/US/2006/ WO/2007/ G01R מערכת ריבוב חצי אוטומאטית עבור בדיקה אוטומאטית של שבבים מוליכים למחצה 30/10/2006 SKIN REPAIR ACCELERATING THERAPEUTIC AGENT CONTAINING GHRELIN AND DERIVATIVES THEREOF OR SUBSTANCE ACTING ON GHS-RLa AS ACTIVE INGREDIENT UNIVERSITY OF MIYAZAKI JP 21/11/ PCT/JP/2006/ WO/2007/ INDEXABLE INSERT SUMITOMO ELECTRIC HARDMETAL CORP JP 21/11/ PCT/JP/2006/ WO/2007/ B23B שימת הניתן לסימון 2555

54 07/11/2006 AEROSOL FORMULATION FOR INHALATION BOEHRINGER INGELHEIM INTERNATIONAL GMBH EP /11/2005 PCT/EP/2006/ WO/2007/ A61K פורמולציה בצורת תרסיס עבור אינהלציה 09/11/2005 IDENTIFICATION AND CHARACTERIZATION OF FUNCTION- BLOCKING ANTI-ED-B- FIBRONECTIN ANTIBODIES MORPHOSYS AG C12N זיהוי ואפיון של נוגדנים אנטי ED B פיברונקטין בעלי פונקציה חוסמת PCT/EP/2005/ WO/2007/ /11/2006 IMAGING SYSTEM AND METHOD FOR A STENCIL PRINTER SPEEDLINE TECHNOLOGIES, INC. US 11/ /11/2005 PCT/US/2006/ WO/2007/ H05K מערכת הדמיה ושיטה למדפסת סטנסיל 06/11/2006 SOL-GEL PROCESS FOR THE MANUFACTURE OF MOULDS FOR PHOTOCATALYTIC PROCESSES P.C.R S.r.l OF IT 2005A /12/2005 PCT/EP/2006/ WO/2007/ B29C תהליך סול ג'ל ליצור תבניות לתהליכים פוטוקטליטים 2556

55 15/11/2006 INDANYL-AND TETRAHYDRONAPHTHYL-AMINO- AZOLINE COMPOUNDS FOR COMBATING ANIMAL PESTS BASF SE US 60/ /11/2005 PCT/EP/2006/ WO/2007/ C07D תרכובות אינדאניל וטטרהידרונפתיל אמינו אזולין לטיפול במטרדי חיות 16/11/2006 SHAPED BODIES BASED ON A CROSS- LINKED GELATINOUS MATERIAL, METHOD FOR PRODUCING THE SAME AND THEIR USE GELITA AG DE /11/2005 PCT/EP/2006/ WO/2007/ A61L גופים מעוצבים המבוססים על חומר גלטיני מוצלב, שיטה לייצורם ושימושיהם 06/11/2006 RECOMBINANT EXPRESSION OF MULTIPROTEIN COMPLEXES USING POLYGENES ETH ZURICH EP /11/2005 PCT/EP/2006/ WO/2007/ C12N ביטוי רקומביננטי של קומפלקסים רבי חלבון תוך שימוש בפוליגנים 20/11/ AMINO-2-ARYLPROPYL AZAINDOLES AND USES THEREOF F. HOFFMANN-LA ROCHE AG US 60/ /11/2005 PCT/EP/2006/ WO/2007/ C07D 3 אמינו 2 ארילפרופיל אזאינדולים ושימושיהם 2557

56 29/11/ PHENYLETHYLAMINO DERIVATIVES AS CALCIUM AND/OR SODIUM CHANNEL MODULATORS NEWRON PHARMACEUTICALS S.P.A. EP /12/2005 PCT/EP/2006/ WO/2007/ C07D תולדות 2 פנילאתילאמינו כמאפננים של תעלת סידן ו/או נתרן 09/11/2006 EPOXY BASED COATINGS SIGMAKALON B.V. EP /11/2005 PCT/EP/2006/ WO/2007/ C09D ציפויים מבוססי אפוקסי 08/11/2006 USE OF PYRROLOQUINOLINE COMPOUNDS TO KILL CLINICALLY LATENT MICROORGANISMS HELPERBY THERAPEUTICS LIMITED GB /11/2005 PCT/GB/2006/ WO/2007/ C07D שימוש בתרכובות פירולוקווינולין להריגת מיקרואורגניזמים רדומים מבחינה קלינית 19/12/ GLOVE WITH HAND-FRIENDLY COATING AND METHOD OF MAKING ANSELL HEALTHCARE PRODUCTS LLC US 11/ /12/2005 PCT/US/2005/ WO/2007/ A41D כפפה עם ציפוי ידידותי ליד ושיטה להכנה 2558

57 23/11/2006 SPIROCYCLIC QUINAZOLINE DERIVATIVES AS PDE7 INHIBITORS PFIZER LIMITED US 60/ /12/2005 US 60/ /04/2006 PCT/IB/2006/ WO/2007/ C07D נגזרות של קווינאזולין ספירוציקלי כמעכבי PDE7 07/12/2006 CTLA-4 ANTIBODY DOSAGE ESCALATION REGIMENS MEDAREX, INC. US 60/ /12/2005 PCT/US/2006/ WO/2007/ A61K משטרי הגברת מינון של נוגדן כנגד 4 CTLA 17/11/2006 ANTI-ALPHA2 INTEGRIN ANTIBODIES AND THEIR USES GLENMARK PHARMACEUTICALS S.A. US 60/ /11/2005 PCT/CA/2006/ WO/2007/ C12N נוגדנים כנגד אינטגרין אלפא 2 ושימושיהם 15/11/2005 DIGITAL VIDEO ZOOMING SYSTEM NDS LIMITED H04N מערכת זום לוידיאו דיגיטאלי PCT/IL/2005/ WO/2007/

58 11/12/2006 ESTROGEN MODULATORS PFIZER PRODUCTS INC. US 60/ /12/2005 US 60/ /06/2006 PCT/IB/2006/ WO/2007/ C07D מודולטורים של אסטרוגן 13/11/ HEPATITIS C VIRUS POLYNUCLEOTIDES, VARIENTS AND PROTEASES VERTEX PHARMACEUTICALS INCORPORATED US 60/ /11/2005 US 60/ /10/2006 PCT/US/2006/ WO/2007/ C07K פולינוקלאוטידים, וריאנטים ופרוטאזים של נגיף הפאטיטוס C 03/11/2006 PROCESS FOR THE PREPARATION OF LIVER CELLS FOR CRYOPRESERVATION CYTONET GMBH &CO. KG DE /11/2005 PCT/EP/2006/ WO/2007/ A01N שיטה להכנת תאי כבד לשמירה על ידי הקפאה 29/11/2006 THERAPEUTIC USES OF A3 ADENOSINE RECEPTOR ANTIBODIES CAN-FITE BIOPHARMA LTD. US 60/ /11/2005 PCT/IL/2006/ WO/2007/ A61K שימושים טיפוליים של נוגדנים של קולטן אדנוסין A3 כן-פייט ביופארמה בע"מ 2560

59 21/11/2006 IMMUNOGLOBULIN FUSION PROTEIN FORMULATIONS WYETH US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61K הרכבים של חלבון אימונוגלובולין מאוחה 08/11/2006 METHOD AND SYSTEM FOR MEDIA INDEPENDENT HANDOVER USING OPERATION, ADMINISTRATION AND MAINTENANCE PROTOCOL INTERDIGITAL TECHNOLOGY CORPORATION US 60/ /11/2005 PCT/US/2006/ WO/2007/ H04Q שיטה ומערכת להעברה בלתי תלויה של מדיה באמצעות שימוש בפרוטוקול הפעלה, אדמיניסטרציה ותחזוקה 31/10/2006 METHODS FOR PRODUCTION OF RECEPTOR AND LIGAND ISOFORMS RECEPTOR BIOLOGIX, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07K שיטות ליצור קולטן וליגנד שווי צורות 28/11/2006 PROCESS FOR THE PREPARATION OF FERRI-SUCCINYLCASEIN VIFOR (INTERNATIONAL) AG. EP /12/2005 PCT/EP/2006/ WO/2007/ C07K תהליך להכנת פרי סוקסיניל קזאין 2561

60 24/10/2006 COMPOSITIONS AND METHODS OF VASCULAR INJURY REPAIR AMORCYTE, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ C12N תכשירים ושיטות לטיפול בפציעה וסקולרית 07/11/2006 COMBINATION OF GLYCOISOFORMS FOR THE TREATMENT OR PREVENTION OF SEPTICEMIA, TRANSGENIC CELL LINE THAT PRODUCES ERYTHROPOIETIN GLYCOISOFORMS, PHARMACEUTICAL COMPOSITION COMPRISING SAID COMBINATION PROTECH PHARMA, S.A. AR P /11/2005 PCT/ES/2006/ WO/2007/ C07K שילוב של גליקואיזופורמים לטיפול או מניעה של הרעלת דם, תאים טרנסגנים שמייצרים גליקואיזופורמים של אריתרופואיטין, תכשיר רפואי המשלב את הקומבינציה האמורה לעיל 23/10/2006 BROMINATED BUTADIENE/VINYL AROMATIC COPOLYMERS, BLENDS OF SUCH COPOLYMERS WITH A VINYL AROMATIC POLYMER, AND POLYMERIC FOAMS FORMED FROM SUCH BLENDS DOW GLOBAL TECHNOLOGIES INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ C08F קופולימרים ארומטיים של בוטאדיאן/ויניל מותמרים בברום, תערובות של קופולימרים כאלה עם פולימר ויניל ארומטי, וקצפים שנוצרו מתערובות אלו 2562

61 08/11/2006 METHODS, COMPOSITIONS, AND KITS FOR THE TREATMENT OF MEDICAL CONDITIONS COMBINATORX, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61K שיטות, הרכבים וערכות לטיפול במצבים רפואיים 03/11/2006 PROCESS FOR ELIMINATING HYDROGEN SULPHIDE AND ODOURS FROM WASTEWATER SYSTEMS ROMOLD GMBH DE /11/2005 PCT/EP/2006/ WO/2007/ B01D תהליך לסילוק מימן גפריתי וצחנה ממערכות מי שפכים 02/11/2006 PROCESS FOR THE PRODUCTION OF OLIGOSACCHARIDES CLASADO INC. GB /11/2005 PCT/EP/2006/ WO/2007/ C12P תהליך לייצור אוליגוסכרידים 15/11/2006 METHODS FOR ISOLATING PROPARGYLATED AMINOINDANS TEVA PHARMACEUTICAL INDUSTRIES LTD. US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07C דרכים לבודד פרופארג'יל אמינואינדאנים טבע תעשיות פרמצבטיות בע"מ 2563

62 13/11/2006 COMPOSITIONS AND METHODS FOR THE TREATMENT OF ADDICTION AND OTHER NEUROPSYCHIATRIC DISORDERS BOARD SUPERVISORS OF LOUISIANA STATE UNIVERSITY & AGRICULTURAL & MECHANICAL COLLEGE US 60/ /11/2005 US 60/ /02/2006 PCT/US/2006/ WO/2007/ A61K הרכבים ושיטות לטיפול בהתמכרות והפרעות נאורופסיכיאטריות אחרות 07/11/2006 IMAGE ENHANCEMENT IN THE MOSAIC DOMAIN D-BLUR TECHNOLOGIES LTD. US 60/ /11/2005 PCT/IL/2006/ WO/2007/ G06T שיפור תמונה בתחום המוזאיקה ד-בלור טכנולוגיות בע"מ 05/05/2006 BOLT-A-BLOK-A SYSTEM FOR UNITIZED, POST-TENSIONED MASONRY STRUCTURES ROGER F. MARSH US 11/ /11/2005 PCT/US/2006/ WO/2007/ E04C BLOK A BOLT מערכת ליצירת מבנים מלוחות בנייה מאוחדים לאחר שחרור מאמצים 2564

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64 08/11/2006 SELF-PROTECTION SYSTEM FOR COMBAT VEHICLES OR OTHER OBJECTS TO BE PROTECTED RHEINMETALL WAFFE MUNITION GMBH DE /11/2005 PCT/EP/2006/ WO/2007/ F41H מערכת הגנה עצמית לרכבים קרביים או עצמים אחרים שיש להגן עליהם 15/11/2006 GAN CRYSTAL SHEET MOSAIC CRYSTALS LTD. US 60/ PCT/IL/2006/ WO/2007/ /11/ C30B משטח גביש של גליום ניטריד מוזאיק קריסטלס בע"מ 09/11/2006 DEVICE PROVIDING A SECURE WORK ENVIRONMENT AND UTILIZING A VIRTUAL INTERFACE ELECTRONIC PLASTICS, LLC US 60/ /11/2005 PCT/US/2006/ WO/2007/ G06F התקן המספק סביבת עבודה מאובטחת המשתמש בממשק וירטואלי 12/11/2006 METHOD FOR NON-AUTOLOGOUS CARTILAGE REGENERATION CARTICURE LTD US 60/ /11/2005 US 60/ /06/2006 PCT/IL/2006/ WO/2007/ C12N שיטה לרגנרציה לא עצמונית של סחוס קרטיקיור בע"מ 2566

65 27/11/2006 CHEMICAL PROCESS FOR THE PREPARATION OF AN AMIDO- PHENOXYBENZOIC ACID COMPOUND C07D תהליך כימי להכנת תרכובת של חומצה אמידו פנוקסיבנזואית ASTRAZENECA AB US 60/ PCT/GB/2006/ WO/2007/ /11/ /11/2006 IMINOPROPENE COMPOUND AND USE THEREOF SUMITOMO CHEMICAL COMPANY, LIMITED JP 01/12/ JP /05/2006 PCT/JP/2006/ WO/2007/ C07D תרכובת אימינופרופן ושימוש מזה 09/11/2006 COMPOSITION AND METHOD FOR RECYCLING SEMICONDUCTOR WAFERS HAVING LOW-K DIELECTRIC MATERIALS THEREON ADVANCED TECHNOLOGY MATERIALS, INC. US 60/ /11/2005 US 60/ /01/2006 US 60/ /06/2006 US 60/ /08/2006 PCT/US/2006/ WO/2007/ H01L תרכובת ושיטה למחזור פרוסות מוליכות למחצה בעלות חומרי K נמוך שאינם מוליכי חשמל מזה 2567

66 15/11/2006 COMPOSITIONS AND METHODS FOR MODULATING HEMOSTASIS THE CHILDREN'S HOSPITAL OF PHILADELPHIA US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07K תרכובות ושיטות לאפנן המוסטאזיס 10/10/2006 TRANSDERMAL THERAPEUTIC SYSTEM NOVARTIS AG US 60/ /12/2005 PCT/US/2006/ WO/2007/ A61K מערכת רפואית תת עורית 23/11/2006 IMPROVED SEMI-CONTINUOUS TWO-COMPONENT METHOD FOR OBTAINING A COMPOSITE EXPLOSIVE CHARGE WITH POLYURETHANE MATRIX EURENCO FRANCE FR /11/2005 PCT/FR/2006/ WO/2007/ C06B שיטה משופרת חצי המשכית דו שלבית להשגת מטען נפץ מרוכב עם מטריקס של פוליאורתאן 20/11/2006 1,5-SUBSTITUTED INDOL-2-YL AMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG EP /11/2005 PCT/EP/2006/ WO/2007/ C07D תולדות אינדול 2 יל אמיד המותמר בעמדה 1,5 2568

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75 21/11/2006 PHARMACEUTICAL COMPOSITIONS COMPRISING AZD2171, PROCESSES FOR THEIR MANUFACTURE AND USE THEREOF IN THE MANUFACTURE OF MEDICAMENTS AND AS MEDICAMENTS FOR PRODUCING AN ANTIANGIOGENIC AND/OR VASCULAR PERMEABILITY REDUCING EFFECT ASTRAZENECA AB GB /11/2005 PCT/GB/2006/ WO/2007/ A61K תכשירי רוקחות המכילים,AZD171 תהליכים להכנתם ושימוש בהם בייצור תרופות וכתרופות ליצירת אפקט נוגד היווצרות כלי דם ו/או מפחית חדירות כלי דם 17/11/2006 SPIROCYCLIC COMPOUNDS AS HDAC INHIBITORS MERCK & CO., INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07D תרכובות ספירוציקליות כמעכבים ל HDAC 21/11/ (PHENYL OR HETEROCYCLIC)-1H- PHENANTRHO[9,10-D]IMIDAZOLES AS MPGES-1 INHIBITORS MERCK FROSST CANADA LTD US 11/ /11/2005 PCT/CA/2006/ WO/2007/ C07D 2 (פניל או הטרוציקיל) H1 פננטרו [10,9 אימידזולים כמעכבים ל MPGES 1 D] 2577

76 16/11/2006 DRINK DISPENSING VALVE AND DISPENSING VALVE-DRINK RESERVOIR ASSEMBLY BRAVILOR HOLDING B.V. NL /11/2005 PCT/NL/2006/ WO/2007/ B67D שסתום מזיגת משקה והתקן הכולל שסתום מזיגה מיכל משקה 17/11/2006 LONGITUDINALLY REINFORCED CURED IN PLACE LINER AND REINFORCED COATING INA ACQUISITION CORP. US 11/ /11/2005 PCT/US/2006/ WO/2007/ F16L ציפוי פנימי מוקשה במקום בעל חיזוקים אורכיים וציפויים מחוזקים 10/11/2006 NEEDLE FOR PUNCTURING POWDER CAPSULES FOR INHALATION BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG DE /11/2005 PCT/EP/2006/ WO/2007/ A61M מחט לניקוב קפסולות המכילות אבקה עבור אינהלציה 2578

77 16/11/ ALLYLAMINO-17- DEMETHOXYGELDANAMYCIN POLYMORPHS AND FORMULATIONS KOSAN BIOSCIENCES, INC. US 60/ /11/2005 US 60/ /05/2006 US 11/ /11/2006 PCT/US/2006/ WO/2007/ C07D הרכבים ופולימורפים של 17 אלילאמינו 17 דמתוקסי גלדאנאמיצין 25/10/2006 SUBSTITUTED 5-PHENYL-3,6- DIHYDRO-2-OXO-6H- [1,3,4]THIADIAZINES MERCK PATENT GMBH DE /11/2005 PCT/EP/2006/ WO/2007/ C07D 5 פניל 6,3 דיהידרו 2 אוקסו H6 1,3,4 ]]תיאדיאזינים מותמרים 25/10/2006 3,6-DIHYDRO-2-OXO-6H- (1,3,4)THIADIAZINE DERIVATIVES MERCK PATENT GMBH DE /11/2005 PCT/EP/2006/ WO/2007/ C07D תולדות של 6,3 דיהידרו 2 אוקסו H6 [1,3,4 ]תיאדיאזינים 2579

78 15/11/2006 AGENT FOR USE IN THE CASE OF FRUCTOSE INTOLERANCE PRO NATURA GESELLSCHAFT FUR GESUNDE ERNAHRUNG MBH DE /11/2005 DE /11/2005 DE /12/2005 DE /12/2005 DE /01/2006 DE /01/2006 DE /01/2006 US 60/ /01/2006 US 60/ /01/2006 DE /03/2006 DE /03/2006 DE /03/2006 US 60/ /07/2006 US 60/ /07/2006 PCT/IB/2006/ WO/2007/ A61K תכשיר לשימוש במקרה של אי סבילות פרוקטוזה 23/11/2006 AGENT FOR REDUCING THE USEABLE CALORIE CONTENT OF FOOD AND FOR THERAPEUTIC REUDCTION OF WEIGHT, IN PARTICULAR FOR USE IN THE CASE OF ADIPOSITY (OBESITY) PRO NATURA GESELLSCHAFT FUR GESUNDE ERNAHRUNG MBH DE /11/2005 DE /12/2005 DE /12/2005 DE /12/2005 DE /01/2006 US 60/ /01/2006 DE /03/2006 DE /03/2006 US 60/ /07/2006 PCT/EP/2006/ WO/2007/ A23L תכשיר עבור הקטנת כמות הקלוריות השימושית באוכל ועבור הורדת משקל תראפיוטית, במיוחד לשימוש במקרה של שומן (שמנות) 2580

79 23/11/2006 AGENT FOR USE IN THE CASE OF DISORDERS OF BLOOD SUGAR METABOLISM, INCLUDING DIABETES PRO NATURA GESELLSCHAFT FUR GESUNDE ERNAHRUNG MBH DE /11/2005 DE /12/2005 DE /01/2006 US 60/ /01/2006 DE /03/2006 US 60/ /07/2006 PCT/EP/2006/ WO/2007/ A21D תכשיר לשימוש במקרה של מחלות של מטבוליזם של סובר בדם, כולל סכרת 15/11/2006 METHOD FOR TRAINING NEURAL NETWORKS BERNADETTE GARNER UA /11/2005 PCT/AU/2006/ WO/2007/ G06N שיטה לסיגול רשתות נוירונים 13/11/2006 SUBSTITUTED PHENYLPIPERIDINES WITH SEROTONINERGIC ACTIVITY AND ENHANCED THERAPEUTIC PROPERTIES AUSPEX PHARMACEUTICALS, INC. US 60/ /11/2005 US 60/ /12/2005 PCT/US/2006/ WO/2007/ C07D פנילפיפרידינים מותמרים עם פעילות סרוטונינרגטית ותכונות טיפוליות מוגברות 2581

80 22/11/2006 IMMUNOSTIMULATORY OLIGORIBONUCLEOTIDES COLEY PHARMACEUTICAL GROUP, INC. US 60/ /11/2005 US 60/ /03/2006 PCT/US/2006/ WO/2007/ C12N אוליגוריבונוקליאוטידים ממריצים של מערכת החיסון 20/11/ AMINO-1-ARYLPROPYL INDOLES AND AZA-SUBSTITUTED INDOLES F. HOFFMANN-LA ROCHE AG US 60/ /11/2005 PCT/EP/2006/ WO/2007/ C07D 3 אמינו 1 ארילפרופיל אינדולים ואינדולים מותמרים ב AZA 22/11/2006 OIL-IN-WATER EMULSION AND ITS USE FOR THE DELIVERY OF FUNCTIONALITY NESTEC S.A. EP /11/2005 PCT/EP/2006/ WO/2007/ A61K אמולסית שמן בתוך מים ושימושה לשחרור תפקודיות 22/11/2006 EASILY DISPERSIBLE LIPIDIC PHASE NESTEC S.A. EP /11/2005 PCT/EP/2006/ WO/2007/ A23D חלוקה של שלב ליפידי בקלות 2582

81 22/11/2006 OIL-IN-WATER EMULSION FOR CREATING NEW PRODUCT CONSISTENCIES NESTEC S.A. EP /11/2005 PCT/EP/2006/ WO/2007/ B01F אמולסית שמן בתוך שמן עבור ייצור עקבי של מוצר חדש 14/11/2006 PRESSURE EXCHANGER ROVEX LIMITED GB PCT/GB/2006/ WO/2007/ /11/ F04F חלפן לחץ 16/11/2006 COMPOSITIONS AND METHODS OF TOPICAL APPLICATION AND TRANSDERMAL DELIVERY OF BOTULINUM TOXINS WITH REDUCED NON-TOXIN PROTEINS REVANCE THERAPEUTICS, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61K הרכבים ושיטות לאפליקציה חיצונית ולהעברה דרך העור של רעלני בוטולינום עם הפחתה בחלבונים שאינם רעלנים 17/11/2006 SEWAGE TREATMENT AUSTRALIAN NUCLEAR SCIENCE AND TECHNOLOGY ORGANISATION AU /11/2005 PCT/AU/2006/ WO/2007/ C02F טיפול בשפכים 2583

82 13/11/2006 IRRIGATION EMITTER STAKE NETAFIM LTD FR /11/2005 PCT/IL/2006/ WO/2007/ A01G מוט להחזקת צינור השקייה נטפים בע"מ 23/11/2006 PATCH ANTENNA ELEMENT AND APPALICATION THEREOF IN A PHASED ARRAY ANTENNA ELTA SYSTEMS LTD. US 11/ /12/2005 PCT/IL/2006/ WO/2007/ H01Q גורם מוסף לאנטנה וישומו במערך אנטנות בעל מספר מופעים אלתא מערכות בע"מ 27/11/2006 WASHING DEVICE CREAHOLIC S.A. CH 1890/05 PCT/CH/2006/ WO/2007/ /11/ E03C התקן לשטיפה 27/11/2006 PRODRUG ER?-SELECTIVE SUBSTANCES, METHODS FOR THE PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS CONTAINING SAID COMPOUNDS BAYER SCHERING PHARMA AG DE /11/2005 PCT/EP/2006/ WO/2007/ C07J מטרימי תרופות של חומרים הסלקטיבים ל?,ER שיטות לייצורם ותכשירי רוקחות המכילים את התרכובות הללו 2584

83 17/11/2006 PROCESS FOR OBTAINING A TRIGLYCERIDE-RICH REFINED AVOCADO OIL, AND OIL WHICH CAN BE OBTAINED BY MEANS OF SUCH A PROCESS LABORATOIRES EXPANSCIENCE US 60/ /11/2005 FR /11/2005 PCT/EP/2006/ WO/2007/ C11B תהליך לקבלת שמן אבוקדו מזוקק עשיר בטריגליצריד, ושמן שניתן להפיק באמצעות תהליך כזה 22/11/2006 COMPOSITIONS AND METHODS FOR MODULATING GATED ION CHANNELS PAINCEPTOR PHARMA CORPORATION US 60/ /11/2005 PCT/CA/2006/ WO/2007/ C07D תכשירים ושיטות לאפנון תעלות יונים בעלות שערים 11/08/2006 WATERING SYSTEM FOR WATERING PLANTS PLANTCARE AG. CH 1866/05 23/11/2005 PCT/CH/2006/ WO/2007/ A01G מערכת השקיה להשקיית צמחים 2585

84 30/11/2006 NONCOMPETITIVE DOMAIN ANTIBODY FORMATS THAT BIND INTERLEUKIN 1 RECEPTOR TYPE 1 DOMANTIS LIMITED US 60/ /12/2005 PCT/GB/2006/ WO/2007/ C07K צורות נוגדנים שאינם מכילים תחום תחרותי ואשר קושרים קולטן אינטרלוקין מטיפוס 1 20/12/2005 METHOD AND SYSTEM FOR DELIVERING MESSAGES IN A COMMUNICATION SYSTEM SKYPE LIMITED US 11/ /11/2005 PCT/EP/2005/ WO/2007/ H04L שיטה ומערכת להעברת הודעות במערכת תקשורת 13/10/2006 DEVICE FOR PRODUCING A STACKING PROJECTION AND CONTAINER WITH SAME SEDA S.P.A. EP /11/2005 PCT/EP/2006/ WO/2007/ B31B התקן ליצור היטל ערימה ומיכל המכיל התקן זה 21/11/2006 MICROBIAL OXYGEN ABSORBER CHR. HANSEN A/S DK PA /11/2005 US 60/ /11/2005 PCT/DK/2006/ WO/2007/ A23L סופח חמצן חיידקי 2586

85 22/11/2006 OXADIAZOLE DERIVATIVES WITH CRTH2 RECEPTOR ACTIVITY 7TM PHARMA A/S GB /11/2005 PCT/EP/2006/ WO/2007/ C07D תולדות אוקסאדיאזול בעלות פעילות קולטן CRTH 2 16/11/2006 IR-ABSORBING INTAGLIO INK SICPA HOLDING S.A. EP /11/2005 PCT/EP/2006/ WO/2007/ C09D דיו ליציקות הסופג קרינת IR 23/11/2006 METHOD FOR PRODUCING 5-FLUORO- 1,3-DIALKYL-1H-PYRAZOL-4- CARBOXYLIC ACID CHLORIDES BAYER CROPSCIENCE AG DE /12/2005 PCT/EP/2006/ WO/2007/ C07D שיטה להכנת כלורידים של 5 פלואורו 3,1 דיאלקיל H1 פיראזול 4 חומצה קרבוקסילית 30/11/2006 COMPETITIVE DOMAIN ANTIBODY FORMATS THAT BIND INTERLEUKIN 1 RECEPTOR TYPE 1 DOMANTIS LIMITED US 60/ /12/2005 PCT/GB/2006/ WO/2007/ C07K צורות נוגדנים בעלות איזורים תחרותיים ואשר קושרים אינטרלוקין 1 לקולטן מטיפוס

86 08/12/2006 THERAPEUTIC VACCINE AC IMMUNE S.A. EP EP PCT/EP/2006/ WO/2007/ /12/ /05/ C07K חיסון טיפולי 19/04/2006 ENANTIOSELECTIVE PREPARATION OF BENZIMIDAZOLE DERIVATIVES AND THEIR SALTS RATIOPHARM GMBH DE /12/2005 PCT/EP/2006/ WO/2007/ C07D הכנה אננטיובררנית של תולדות בנזאימידזול ומלחיהן 12/12/2006 TRANSMISSION CONTROL PROTOCOL WITH PERFORMANCE ENHANCING PROXY FOR DEGRADED COMMUNICATION CHANNELS VIASAT INC. US 11/ /12/2005 PCT/US/2006/ WO/2007/ H04L פרוטוקול בקרת שידור הכולל מתווך עבור ערוצי תיקשורת בעלי התדרדרות בביצועיהם 22/12/2005 PROVISIONING OF USER INFORMATION TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) PCT/SE/2005/ WO/2007/ H04M הפצת מידע משתמש 2588

87 15/11/2006 NEW DIAMOND USES/APPLICATIONS BASED ON SINGLE-CRYSTAL CVD DIAMOND PRODUCED AT HIGH GROWTH RATE CARNEGIE INSTITUTION OF WASHINGTON US 60/ /11/2005 PCT/US/2006/ WO/2007/ C30B שימושים ויישומים חדשים של יהלומים המבוססים על יהלום בעל גביש יחידי המיוצר על ידי שיקוע אדים כימיים( CVD ( בקצב גידול גבוה 30/10/2006 A HIGH STRENGTH MARTENSITIC STEEL ALLOY CRS HOLDINGS, INC. US 11/ /11/2005 PCT/US/2006/ WO/2007/ C22C סגסוגת פלדה מרטינסיטיק בעלת חוזק רב 11/12/2006 FUEL CELLS AND ELECTRODE MEMBRANE ASSEMBLIES CONTAINING A PROTEIN EXCHANGE MEMBRANE GEORGIA TECH RESEARCH CORPORATION US 60/ /12/2005 PCT/US/2006/ WO/2007/ H01M תאי דלק והרכבים של אלקטרודות קרומיות המכילים קרומים להחלפת חלבונים 2589

88 17/11/2006 DESLORATADINE CRYSTALLINE FORMS MIXTURES HAVING A LOW LEVEL OF RESIDUAL SOLVENTS TEVA PHARMACEUTICAL INDUSTRIES LTD. US 60/ /11/2005 PCT/IB/2006/ WO/2008/ C07D תערובות של צורות קריסטליניות של דסלורטדין המכילות רמה נמוכה של ממסים שייריים טבע תעשיות פרמצבטיות בע"מ 17/11/2006 MALODOR REDUCING COMPOSITIONS AND METHODS COLGATE-PALMOLIVE COMPANY US 60/ /11/2005 PCT/US/2006/ WO/2007/ C11D הרכבים ושיטות להפחתת סרחון 17/11/2006 OIL-IN-WATER FORMULATION OF AVERMECTINS CHEMINOVA A/S DK PA /11/2005 US 60/ /11/2005 PCT/DK/2006/ WO/2007/ A01N תערובת שמן במים של אוורמקטינים 2590

89 16/11/2006 PHARMACEUTICAL COMPOSITION AND METHOD FOR REGULATING ABNORMAL CELLULAR PROLIFERATION THE GOVERNMENT OF THE UNITED STATES OF AMERICA AS REPRESENTED BY THE SECRETARY OF THE DEPARTMENT OF HEALTH AND HUMAN SERVICES NATIONAL INSTITUTES OF HEALTH OFFICE OF US 60/ /11/2005 PCT/IL/2006/ WO/2007/ A61K תכשירים ושיטות לבקרה של ריבוי תאים אבנורמלי תל השומר-מחקרים,תשתית ושירותים רפואיים בע"מ 16/11/2006 PHARMACEUTICAL COMPOSITIONS COMPRISING BUPRENORPHINE SCHERING-PLOUGH LTD. US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61K תכשירים רוקחיים המכילים בופרנורפין 18/10/2006 TIMING OF A Q-SWITCH TO SUPPRESS PRE-LASING OF THE LASER SELEX SENSORS AND AIRBORNE SYSTEMS LIMITED GB /11/2005 EP /11/2005 PCT/GB/2006/ WO/2007/ H01S תזמון של מפסק Q להנחתת פרה ליסינג של לייזר 2591

90 14/11/2006 SALMONELLA BASED ORAL VACCINES FOR ANTHRAX UNIVERSITY OF MARYLAND BIOTECHNOLOGY INSTITUTE US 60/ /11/2005 PCT/US/2006/ WO/2008/ A61K חיסון מבוסס סלמונלה נגד אנטרקס למתן דרך הפה 14/11/2006 TOUCH-SAFE SOCKET POULSEN, CARSTEN, HORNSHOJ DK PA /11/2005 PCT/DK/2006/ WO/2007/ H01R שקע מוגן מנגיעה 28/11/2006 DEVICE, SYSTEM AND METHOD OF PERFORMING AN ADMINISTRATIVE OPERATION ON A SECURITY TOKEN K.K. ATHENA SMARTCARD SOLUTIONS US 60/ /11/2005 PCT/IL/2006/ WO/2007/ G06F התקן, מערכת ושיטה לביצוע פעולה אדמיניסטרטיבית על טוקן אבטחה 16/11/2006 MEDICAL FLUID INJECTION SYSTEM ACIST MEDICAL SYSTEMS, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61M מערכת להזרקת נוזל רפואי 2592

91 28/11/2006 RECOMBINANT MONOVALENT ANTIBODIES AND METHODS FOR PRODUCTION THEREOF GENMAB A/S US 60/ /11/2005 US 60/ /10/2006 US 60/ /10/2006 PCT/DK/2006/ WO/2007/ C07K נוגדנים מונוולנטים רקומביננטים ושיטות לייצורם 01/12/2006 FUSED HETEROCYCLIC COMPOUND TAKEDA PHARMACEUTICAL COMPANY LIMITED JP 02/12/ JP /03/2006 PCT/JP/2006/ WO/2007/ C07D תרכובות הטרוציקליות מאוחות 23/11/2006 ERYTHROPOIETIN POLYPEPTIDES, THEIR PREPARATION AND USES THEREOF LABORATOIRES SERONO SA EP /11/2005 EP /11/2005 US 60/ /12/2005 US 60/ /12/2005 PCT/EP/2006/ WO/2007/ C07K אריתרופויאטין פוליפפטידים, הכנתם ושימושים שלהם 2593

92 21/11/2006 HYBRID ANTIGEN BINDING MOLECULES, THEIR PREPARATION AND USE LABORATOIRES SERONO SA US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07K מולקולות היברידיות הקשורות אנטיגנים, הכנתן ושימושיהן 16/11/2006 INTERFERON IN INFLUENZA ARES TRADING S.A. EP /11/2005 US 60/ /11/2005 PCT/EP/2006/ WO/2007/ A61K אינטרפרון בשפעת 21/11/2006 DEVICES AND METHODS FOR HIGH- PRESSURE REFOLDING OF PROTEINS BAROFOLD, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ B01L התקנים ושיטות להחזקת דוגמאות של חלבונים תחת לחץ גבוה 29/11/2006 ELECTROCHEMICAL TREATMENT OF SOLUTIONS CONTAINING HEXAVALENT CHROMIUM INDUSTRIE DE NORA S.P.A IT MI2005A /11/2005 PCT/EP/2006/ WO/2007/ C02F טיפול אלקטרוכימי של תמיסות המכילות כרום הקסאוולנטי 2594

93 13/12/2006 COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES AMBRX, INC. US 60/ /12/2005 US 60/ /12/2005 PCT/US/2006/ WO/2007/ A61K תכשירים המכילים חומצות אמיניות ופוליפפטידים שאינם טבעיים, שיטות הנוגעות לחומרים הללו ושימושים בהם 07/12/2006 PYRIMIDINE DERIVATIVES PFIZER LIMITED US 60/ /12/2005 PCT/IB/2006/ WO/2007/ C07D תולדות פירימידין 14/11/2006 METHODS FOR PREDICTION AND PROGNOSIS OF CANCER, AND MONITORING CANCER THERAPY BAYER HEALTHCARE LLC US 60/ /11/2005 PCT/US/2006/ WO/2007/ G01N שיטות לחיזוי וניבוי של סרטן, וניטור טיפול בסרטן 09/10/2006 SOLDERING DEVICE WITH COMPUTER- BASED SENSOR SYSTEM THOMAS ALLETZHAEUSER DE /11/2005 PCT/DE/2006/ WO/2007/ B23K מכשיר הלחמה עם מערכת חישן מבוססת מחשב 2595

94 15/11/2006 PUMP APPARATUS AND METHODS FOR USING SAME FOAM IN PLACE CO. LTD. US 60/ /11/2005 US 60/ /05/2006 PCT/IB/2006/ WO/2007/ F04C התקן משאבה ושיטות לשימוש בה 14/11/2006 RAPID NON-EQUILIBRIUM DECOMPRESSION OF MICROORGANISM-CONTAINING WASTE STREAMS SHEPHERD, SAMUEL, L. US 11/ /11/2005 PCT/US/2006/ WO/2007/ C12H הסרת לחץ מהירה שלא בשיווי משקל של מי שפכים המכילים מיקרו אורגניזמים 26/11/2006 FLEXIBLE ELECTRIC LOAD MANAGEMENT SYSTEM AND METHOD THEREFOR COMPUTERIZED ELECTRICITY SYSTEMS LTD. US 60/ /11/2005 PCT/IL/2006/ WO/2007/ G06F מערכת גמישה לניהול עומסים חשמליים ושיטה עבורה 2596

95 14/11/2006 IMPROVED SYNTHESES AND PREPARATIONS OF INTERMEDIATES AND NEW POLYMORPHS THEREOF USEFUL FOR THE PREPARATION OF DONEPEZIL HYDROCHLORIDE MEDICHEM S.A. US 60/ /11/2005 PCT/IB/2006/ WO/2007/ C07D סינתיזה משופרת של חומרי ביניים ופולימורפים חדשים לשימוש בהכנת דונפזיל הידרוכלוריד 14/09/2006 METHOD OF INCREASING THE RANGE OF A SUBCALIBRE SHELL AND SUBCALIBRE SHELLS WITH LONG RANGE BAE SYSTEMS BOFORS AB SE /11/2005 PCT/SE/2006/ WO/2007/ F42B שיטה להגדלת טווח פגז תת קוטר ופגזי תת קוטר ארוכי טווח 15/11/2006 N4-PHENYL-QUINAZ0LINE-4 -AMINE DERIVATIVES AND RELATED COMPOUNDS AS ERBB TYPE I RECEPTOR TYROSINE KINASE INHIBITORS FOR THE TREATMENT OF HYPERPROLIFERATIVE DISEASES ARRAY BIOPHARMA INC. US 60/ /11/2005 US 60/ /06/2006 PCT/US/2006/ WO/2007/ C07D נגזרות N4 פניל קינאזולין 4 אמין ותרכובות קשורות כמעכבי טירוזין קינאז לרצפטור ERBB סוג I לטיפול במחלות הקשורות להתרבות מהירות של תאים 2597

96 08/08/ B23B כלי חיתוך בעל פני שטח מצופה 08/08/2007 SURFACE -COATED CUTTING TOOL SUMITOMO ELECTRIC HARDMETAL CORP JP 31/08/ PCT/JP/2007/ WO/2008/ SURFACE-COATED CUTTING TOOL SUMITOMO ELECTRIC HARDMETAL CORP JP 31/08/ PCT/JP/2007/ WO/2008/ B23B כלי חיתוך בעל פני שטח מצופה 08/12/2006 IMMUNOGENIC COMPOSITION BASED ON CONDITIONALLY LIVE VIRION AND METHOD FOR PRODUCING THE SAME KARP, Nelson, M. US 60/ /12/2005 PCT/US/2006/ WO/2007/ C12N תכשיר אימונוג'יני על בסיס ויריון חי בתנאי ושיטה לייצורו 2598

97 28/11/2006 POINT TO MULIPOINT DEVICE FOR COMMUNICATION WITH A PLURALITY OF TELECOMMUNICATIONS UNITS AIRSPAN NETWORKS INC. GB /12/2005 GB /06/2006 PCT/GB/2006/ WO/2007/ H04B נקודה לאמצעי רב נקודתי לתקשורת עם יחידות טלקומוניקציה מגוונות 28/11/2006 POINT TO MULTIPOINT DEVICE FOR COMMUNICATION WITH A PLURALITY OF TELECOMMUNICATIONS UNITS AIRSPAN NETWORKS INC. GB /12/2005 GB /06/2006 PCT/GB/2006/ WO/2007/ H04B נקודה לאמצעי רב נקודתי לתקשורת עם יחידות טלקומוניקציה מגוונות 07/11/2006 VPLS REMOTE FAILURE INDICATION CORRIGENT SYSTEMS LTD. US 60/ /11/2005 PCT/IL/2006/ WO/2007/ H04J אינדיקציית כשלון VPLS מרחוק קוריגנט מערכות בע"מ 2599

98 12/12/2006 SYSTEM AND METHOD FOR DELIVERING SHORT MESSAGES ON DO AND 1X NETWORKS QUALCOMM INCORPORATED US 60/ /12/2005 US 11/ /10/2006 PCT/US/2006/ WO/2007/ H04Q מערכת ושיטה להעברת הודעות קצרות על רשתות DO ו X 1 26/10/2006 MESSAGE HANDLING IN AN IP MULTIMEDIA SUBSYSTEM TELEFONAKTIEBOLAGET LM ERICSSON (PUBL) GB /11/2005 PCT/EP/2006/ WO/2007/ H04L טיפול בהודעות בתת מערכת מולטימדיה IP 17/11/2006 FLUORESCENT MEMBRANE INTERCALATING PROBES AND METHODS FOR THEIR USE PHANOS TECHNOLOGIES, INC. AU /11/2005 PCT/US/2006/ WO/2007/ C07D בוחני ממברנה פלורוסנטיים ושיטות לשימוש בהם 2600

99 27/12/2006 COMPOSITIONS CONTAINING, METHODS INVOLVING, AND USES OF NON-NATURAL AMINO ACIDS AND POLYPEPTIDES AMBRX, INC. US 60/ /12/2005 US 60/ /12/2005 US 60/ /12/2005 PCT/US/2006/ WO/2007/ A61K תכשירים המכילים חומצות אמיניות ופוליפפטידים שאינם טבעיים, שיטות המערבות חומרים אלו ושימושים בהם 05/12/2006 LIGANDS THAT HAVE BINDING SPECIFICITY FOR EGFR AND/OR VEGF AND METHODS OF USE THEREFOR DOMANTIS LIMITED US 60/ /12/2005 US 60/ /01/2006 PCT/GB/2006/ WO/2007/ C07K ליגנדים בעלי בררנות קישור ל EGFR ו/או VEGF ושיטות לשימוש בהם 05/12/2006 BISPECIFIC LIGANDS WITH BINDING SPECIFICITY TO CELL SURFACE TARGETS AND METHODS OF USE THEREFOR DOMANTIS LIMITED US 60/ /12/2005 PCT/GB/2006/ WO/2007/ C07K ליגנדים בעלי בררנות כפולה עם בררנות לקישור למטרות על פני שטח התא ושיטות לשימוש בהם 2601

100 09/11/2006 LID FOR A CUP-SHAPED RECEPTACLE SEDA S.P.A. EP PCT/EP/2006/ WO/2007/ /11/ B65D מכסה עבור כלי קיבול בצורת כוס 14/02/2006 A PROCESS AND A DEVICE FOR SURGICAL TREATMENT OF RECTAL AND HAEMORRHOIDAL PROLAPSE THD S.P.A. VIA DELL'INDUSTRIA PCT/IT/2006/ WO/2007/ A61B תהליך והתקן לטיפול ניתוחי של טחורים ושל תמט רקטלי 18/11/2006 NEW PLEUROMUTILIN DERIVATIVE AND ITS USE GLAXO GROUP LIMITED US 60/ /11/2005 PCT/US/2006/ WO/2007/ C07D תולדת פליאורומוטילין חדשה ושימושה 22/11/2006 SEROTONIN TRANSPORTER (SERT) INHIBITORS F. HOFFMANN-LA ROCHE AG EP /12/2005 PCT/EP/2006/ WO/2007/ C07D מעכבים של מוביל של סרוטונין (SERT) 2602

101 20/11/2006 METHODS FOR SYNTHESIS OF 3- AMINO-1-ARYLPROPYL INDOLES F. HOFFMANN-LA ROCHE AG US 60/ /11/2005 PCT/EP/2006/ WO/2007/ C07D שיטות לסינתזה של 3 אמינו 1 ארילפרופיל אינדולים 22/11/2006 2,4,5-TRIPHENYL IMIDAZOLINE DERIVATIVES AS INHIBITORS OF THE INTERACTION BETWEEN P53 AND MDM2 PROTEINS FOR USE AS ANTICANCER AGENTS F. HOFFMANN-LA ROCHE AG US 60/ /12/2005 US 60/ /10/2006 PCT/EP/2006/ WO/2007/ C07D נגזרות של 5,4,2 טריפניל אימידאזולין כמעכבים של האינטראקציה בין חלבונים של P53 ו MDM2 לשימוש כחומרים נגד סרטן 22/11/2006 NOVEL VINYLOGOUS ACIDS DERIVATIVES F. HOFFMANN-LA ROCHE AG EP /12/2005 PCT/EP/2006/ WO/2007/ C07D נגזרות חדשות של חומצות וינילוגיות 2603

102 30/11/2006 CONTAINER VERIFICATION SYSTEM FOR NON-INVASIVE DETECTION OF CONTENTS INNOVATIVE AMERICAN TECHNOLOGY, INC. US 11/ /12/2005 US 60/ /01/2006 US 60/ /01/2006 US 60/ /01/2006 US 60/ /01/2006 US 11/ /02/2006 PCT/US/2006/ WO/2007/ G08B מערכת לאימות מיכל לשם זיהוי לא חודרני של תכולה 17/11/2006 MACHINE AND METHOD FOR PHARMACEUTICAL AND PHARAMACEUTICAL-LIKE PRODUCT ASSEMBLY GLAXO GROUP LIMITED US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61K מכונה ושיטה להרכבת תוצר רוקחי ודמוי רוקחי 20/11/2006 NEUROENDOCRINE TUMOR TREATMENT USING MTOR INHIBITORS NOVARTIS AG GB /11/2005 GB /01/2006 GB /02/2006 GB /04/2006 GB /05/2006 GB /05/2006 EP /09/2006 PCT/EP/2006/ WO/2007/ A61P טיפול בגידול נוירואנדוקריני תוך שימוש במעכבי MTOR 2604

103 22/11/2006 SUBSTITUTED ARYLOXYPROPYLAMINES WITH SEROTONINERGIC AND/OR NOREPINEPHRINERGIC ACTIVITY AUSPEX PHARMACEUTICALS, INC. US 60/ /11/2005 US 60/ /08/2006 PCT/US/2006/ WO/2007/ C07B ארילאוקסיפרופילאמידים מותמרים עם פעילות סרוטונינרגית ו/או נוראפינפרינרגית 20/11/ SUBSTITUTED INDOLE-2- CARBOXAMIDE DERIVATIVES F. HOFFMANN-LA ROCHE AG EP /11/2005 PCT/EP/2006/ WO/2007/ C07D נגזרות של אינדול 2 קרבוקסאמיד המותמרות בעמדה 5 20/11/2006 1,1-DIOXO-THIOMORPHOLINYL INDOLYL METHANONE DERIVATIVES FOR USE AS H3 MODULATORS F. HOFFMANN-LA ROCHE AG EP /11/2005 PCT/EP/2006/ WO/2007/ C07D נגזרות של 1,1 דיאוקסו תיומורפוליניל אינדוליל מתאנון לשימוש כמודולטורים של H3 2605

104 22/11/ HETEROARYL SUBSTITUTED PIPERIDINE DERIVATIVES AS L-CPT1 INHIBITORS F. HOFFMANN-LA ROCHE AG EP /12/2005 PCT/EP/2006/ WO/2007/ C07D תולדות פיפרידין מותמרות עם הטרואריל כמעכבי CPT L1 16/09/2007 ITEM OF TRANSFORMABLE FURNITURE ORT JOINT-STOCK COMPANY GB /09/2006 PCT/IB/2007/ WO/2008/ A47C פריט ריהוט משנה צורה 17/11/2006 COMMUNICATION SYSTEM AND METHOD XYNK PTY LTD AU /11/2005 AU /07/2006 PCT/AU/2006/ WO/2007/ H04L מערכת תקשורת ושיטה 17/11/2006 SCRUBBER FOR CLEANING THE EXHAUST GASES OF A DIESEL ENGINE, METHOD OF OPERATING IT AND CORRESPONDING MARITIME VEHICLE LAB SA FR /11/2005 PCT/FR/2006/ WO/2007/ F01N אמצעי קרצוף לניקוי גזי הפליטה של מנוע דיזל, שיטה לתפעולו וכלי ימי מקביל 2606

105 01/11/2006 BICYCLIC CINNAMIDE COMPOUND EISAI R&D MANAGEMENT CO., LTD. JP /11/2005 JP /07/2006 PCT/JP/2006/ WO/2007/ C07D תרכובת סינאמיד ביציקלית 13/10/2006 LYOPHILIZATION PROCESS AND PRODUCTS OBTAINED THEREBY SCIDOSE LLC. US 11/ /11/2005 PCT/US/2006/ WO/2007/ A61K תהליך ליאופיליזציה ותוצריו 21/11/2006 IMPROVEMENTS TO DOPPLER RADAR SYSTEMS PLEXTEK LIMITED GB /11/2005 GB /01/2006 PCT/EP/2006/ WO/2007/ G01S שיפורים במערכות רדאר דופלר 21/11/2006 FREQUENCY SCANNING ANTENNA PLEXTEK LIMITED GB /11/2005 GB /01/2006 PCT/EP/2006/ WO/2007/ H01Q משושה סורקת תדרים 2607

106 21/11/2006 RADAR SYSTEM PLEXTEK LIMITED GB GB PCT/EP/2006/ WO/2007/ /11/ /01/ G01S מערכת רדאר 17/10/2006 COLD-FORMABLE LAMINATE FOR BLISTER BASE PARTS ALCAN TECHNOLOGY & MANAGEMENT LTD. EP /11/2005 PCT/EP/2006/ WO/2007/ B32B רבד לעיצוב קר עבור חלקים עם בסיס בועית 17/11/2006 INDUCIBLE EXPRESSION SYSTEMS STICHTING VOOR DE TECHNISCHE WETENSCHAPPEN EP /11/2005 PCT/NL/2006/ WO/2007/ C12N מערכת המאפשרת הסקת ביטוי 08/12/2006 ACYL TRANSFERASE USEFUL FOR DECONTAMINATION GENENCOR INTERNATIONAL, INC. US 60/ /12/2005 US 10/ /05/2006 PCT/US/2006/ WO/2007/ C12P אציל טרנספראז המשמש לסילוק חומרים מזהמים 2608

107 13/11/2006 TRANSMIT-POWER CONTROL FOR WIRELESS MOBILE SERVICES TRUEPOSITION, INC US 11/ /11/2005 PCT/US/2006/ WO/2007/ H04B בקרת העברת כח עבור שירותים אלחוטיים ניידים 21/11/2006 THROMBOPOIETIN ACTIVITY MODULATING COMPOUNDS AND METHODS LIGAND PHARMACEUTICALS INC. US 60/ /11/2005 US 60/ /08/2006 PCT/US/2006/ WO/2007/ C07D תרכובות ושיטות לאפנון פעילות תרומבופואיטינית 05/12/2006 CONTAINER BEING PROVIDED WITH AN INNER BAG GREEN BOTTLE LIMITED GB /12/2005 GB /06/2006 PCT/GB/2006/ WO/2007/ B65D מיכל המסופק יחד עם שקית פנימית 2609

108 15/12/ PHARMACEUTICAL COMPOSITION CONTAINING DONEPEZIL HYDROCHLORIDE, TABLETS PRODUCED THEREFROM AND METHOD FOR PRODUCING THE SAME RATIOPHARM GMBH DE /12/2005 EP PCT/EP06/ /08/2006 PCT/EP/2006/ WO/2007/ A61K תכשיר רוקחות המכיל דונפזיל הידרוכלוריד, טבליות המיוצרות ממנו ושיטה לייצורן 18/12/2006 OPTIMIZING WRITE AND WEAR PREFORMANCE FOR A MEMORY MICROSOFT CORPORATION US 11/ /12/2005 PCT/US/2006/ WO/2007/ G06F אופטימיזציה של ביצועי כתיבה ומחיקה עבור זכרון 23/11/2006 METHOD FOR PRODUCING SULFONAMIDES BASF SE DE EP PCT/EP/2006/ WO/2007/ /12/ /11/ C07C שיטה ליצור סולפונאמידים 2610

109 27/11/2006 PRODRUGS OF ER-BETA-SELECTIVE SUBSTANCES METHOD FOR PRODUCTION THEREOF AND PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME BAYER SCHERING PHARMA AG DE /11/2005 PCT/EP/2006/ WO/2007/ C07J מטרימי תרופות של ER בתא חומרים בררניים, שיטה לייצורם ותכשירי רוקחות המכילים אותם 17/11/2006 MAXILLOFACIAL BONE AUGMENTATION USING rhpdgf-bb AND A BIOCOMPATIBLE MATRIX BIOMIMETIC THERAPEUTICS, INC. US 60/ /11/2005 PCT/US/2006/ WO/2007/ A61L הגדלת עצם מקסילופציאלית על ידי שימוש ב BB rhdgf וטריצה ביוקומפטבילית 10/03/2006 SAFETY SYRINGE WITH PLUNGER LOCKING MEANS GLOBAL MEDISAFE HOLDINGS LIMITED AU /11/2005 AU /01/2006 PCT/AU/2006/ WO/2007/ A61M מזרק בטיחותי עם אמצעי נעילת בוכנה 2611

110 18/11/2005 SEGMENTED PHARMACEUTICAL DOSAGE FORMS ACCU-BREAK TECHNOLOGIES, INC A61K צורות מתן תכשיר מקוטעות PCT/US/2005/ WO/2007/ /11/2006 MATERIALS AND METHODS FOR TREATING CHRONIC FIBROTIC DISEASE THE REGENTS OF THE UNIVERSITY OF MICHIGAN US 60/ /12/2005 PCT/US/2006/ WO/2007/ C12Q חומרים ושיטות לטיפול במחלת לייפת כרונית 19/12/2006 PHARMACEUTICAL COMBINATION FOR THE TREATMENT OF LUTS COMPRISING A PDE5 INHIBITOR AND A MUSCARINIC ANTAGONIST PFIZER PRODUCTS INC. US 60/ /12/2005 US 60/ /01/2006 PCT/IB/2006/ WO/2007/ A61K קומבינציות פרמצבטיות לטיפול בתסמינים של דרכי השתן התחתונות המכילים מעכב PDE5 2612

111 28/12/2006 ISOXAZOLINES FOR CONTROLLING INVERTEBRATE PESTS E.I. DU PONT DE NEMOURS AND COMPANY,INC. US 60/ /12/2005 US 60/ /08/2006 US 60/ /11/2006 PCT/US/2006/ WO/2007/ C07D איזוקסזולינים לריסון מזיקים חסרי חוליות 14/11/2006 APPARATUS AND TECHNIQUES FOR FREEZING AND THAWING OF AGRICULTURAL PRODUCE FRESH DEFROST LTD IL /11/2005 PCT/IL/2006/ WO/2007/ A23B מערכות וטכניקות להקפאה והפשרה של תוצרת חקלאית פרש דיפרוסט בע"מ 2613

112 NOTICE UNDER SECTION 26 OF THE PATENTS LAW, The applications, particulars of which are set out below, have been accepted pursuant to Section 17 of the Patents Law. Any person wishing to oppose the grant of a patent on any of the applications published here, may, within three months from the date of this journal, give to the Commissioner of Patents notice under Section 30 of the Patents Law, in the manner prescribed in regulations 57 et seq of the Patents Regulations, Particulars of the applications, where applicable, are given in the following order: [11] [21] Number of application Title of invention Application date [31] [32] [33] Number and date of foreign application convention country. * Int.Cl. [61] Application for patent of addition [62] Divisional application Applicant [72] Inventor [87] International Publication Number Address for service [57] Abridgement of invention (in the language in which the specification is drawn up) *Note: As from Patents and Designs Journal No.1/06, patent applications are classified according to the Eighth Edition of the International Patent Classification (2006) הודעה לפי סעיף 26 לחוק הפטנטים תשכ"ז הבקשות שפרטיהן מתפרסמים להלן קובלו לפי סעיף 17 לחוק הפטנטים. כל המעונין להתנגד למתן פטנט על פי בקשה מהבקשות המתפרסמות רשאי, תוך שלושה חדשים מתאריך יומן זה, להגיש לרשם הפטנטים הודעת התנגדות לפי סעיף 30 לחוק הפטנטים בדרך הקבועה בתקנה 57 ואילך לתקנות הפטנטים, תשכ"ח פרטי הבקשות במידה ויישימים מובאים לפי סדר זה: מספר הבקשה שם האמצאה תאריך הבקשה מספר ותאריך של בקשות החוץ מדינת האגוד *סיווג בינלאומי מהדורה שביעית בקשה לפטנט מוסף בקשת חלוקה המבקש הממציא מס' פרסום של בקשה הבינלאומית מען למסירת מסמכים תקציר האמצאה (בשפה בה ערוך הפירוט) *הערה: החל מיומן הפטנטים והמדגמים מס' 1/06 ניתן ציון לבקשות פטנטים הסיווג לפי המהדורה השמינית של הסיווג הבינלאומי של פטנטים (משנה 2006) 2614

113 ERYTHROPOIETIN ANALOGS אנלוגים לאריתרופיטן [31] 08/ [32] [33] US Int. Cl.8 A61K 038/18, A61P 007/06, C07K 014/505, C12N 005/10, 015/16 KIRIN-AMGEN INC., SWITZERLAND SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] An analog of human erythropoietin having at least one additional site for N-glycosylation at an asparagine residue at any one of amino acid positions 30, 51, 57, 88, 89, 136 and 138 and wherein at least one additional N-linked carbohydrate chain is attached at any one of said amino acid positions. Also claimed are an analog of human erythropoietin comprising a sites in human erythropoietin and an addition of an equal number of nonnaturally occurring glycosylation sites whereby the positions of carbohydrate chains are changed and an analog of human erythropoietin having an additional site for O-glycosylation at amino acid position 123 and wherein an additional O-linked carbohydrate chain is attached at said amino acid position. deletion of one or more glycosylation The applications for division from this application have not yet been published,192290,136189, בקשות חלוקה מבקשה זו שטרם פורסמו. 2615

114 CONSTRUCT FOR INFECTING MAMMALIAN CELLS COMPRISING THE SV40 VP1 CAPSID PROTEIN AND A HISTONE - FREE CONSTITUENT, METHODS OF CONSTRUCTION AND USES THEREOF קונסטרוקט להדבקת תאי יונקים המכיל חלבון מעטפת VP1 של וירוס SV40 ורכיב נטול היסטונים, שיטות לבנייתו ושימושיו [72] Int. Cl.8 A61K 048/00, C07K 014/025, C12N 005/10, 015/37, 015/63, 015/87 YISSUM RESEARCH יישום חברה לפיתוח המחקר של האוניברסיטה העברית בירושלים, ירושלים DEVELOPMENT COMPANY OF הדסית שרותי מחקר רפואי ופיתוח בע"מ, THE HEBREW UNIVERSITY OF JERUSALEM ירושלים HADASIT MEDICAL RESEARCH SERVICES & DEVELOPMENT LTD. ARIELLA OPPENHEIM, ZIV SANDALON, AMOS B. OPPENHEIM LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA אריאלה אופנהיים, זיו סנדלון, עמוס ב. אופנהיים לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] A construct capable of infecting a mammalian cell comprising: semi-purified or pure SV40 VP1 capsid protein or a mixture of SV40 VP1 capsid protein and at least one of semi-purified or pure VP2 and VP3; and a histone-free constituent selected from the group consisting of naked exogenous polynucleotide selected from: DNA encoding an exogenous protein or peptide product, or encoding therapeutic RNA, or itself a therapeutic product, a vector comprising DNA encoding an exogenous protein or peptide product, or encoding therapeutic RNA, or itself a therapeutic product, RNA encoding an exogenous protein or peptide product or itself a therapeutic product, a vector comprising RNA encoding an exogenous protein or peptide product or itself a therapeutic product, and antisense RNA, ribozyme RNA or any RNA or DNA which inhibits or prevents the expression of undesired protein(s) in said mammalian cell; and optionally further comprising operatively linked regulatory elements sufficient for the replication of said exogenous polynucleotide, and/or for the expression of a portion encoded by said polynucleotide, in a mammalian cell. 2616

115 MULTI-ARRAY, MULTI-SPECIFIC ELECTROCHEMILUMINESCENCE TESTING בדיקת אלקטרוכימילומיניסצנציה מולטי-ספציפית רב שורתית [31] / [32] / Int. Cl.8 G01N 033/543 MESO SCALE TECHNOLOGIES, LLC, U.S.A. EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] US US איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] An apparatus for use in the detection of an analyte by electrochemiluminescence comprising a light detector and an electrode (16) having immobilized on a surface thereof a plurality of binding domains (14) comprising binding reagents capable of binding said analyte or capable of binding a binding partner of said analyte. 2617

116 ANTIBODY OR ITS FRAGMENT SPECIFIC TO THE ED-B ONCOFOETAL DOMAIN OF FIBRONECTIN, PROCESS FOR THEIR PRODUCTION AND THEIR USES נוגדן או קטעו ספציפיים לאזור אונקו עוברי B ED של פיברונקטין, תהליך להכנתם ושימושם [31] [87] [32] [33] GB Int. Cl.8 A61K 039/395, 051/10, C07K 016/18, C12N 001/21, 015/13, G01N 033/577, 033/68 PHILOGEN S.R.L., ITALY WO/1997/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] An isolated antibody or antibody fragment which is specific for and binds directly to the ED-B oncofoetal domain of fibronectin (FN), having a dissociation constant (Kd) for ED-B FN of less than 6x10-8 M, when measured as a purified monomer. NUCLEAR TRANSFER WITH DIFFERENTIATED FETAL AND ADULT DONOR CELLS העברה גרעינית של תאי תורם מובחנים עובריים ובוגרים [31] [87] / [32] [33] US Int. Cl.8 A01K 067/027, A61K 035/12, 048/00, C12N 005/06, 015/00, 015/87 UNIVERSITY OF MASSACHUSETTS, U.S.A. WO/1998/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A method of cloning a bovine, comprising: (i) inserting a desired propagating differentiated mammalian cell or cell nucleus into an enucleated mammalian oocyte of the same species as the differentiated cell or cell nucleus, under conditions suitable for the formation of a nuclear transfer (NT) unit; (ii) activating the resultant nuclear transfer 2618

117 unit; (iii) culturing said activated nuclear transfer unit until greater than the 2-cell developmental stage; and (iv) transferring said cultured NT unit to a bovine host mammal such that the NT unit develops into a fetus. HUMAN NEURTURIN RECEPTOR- A (NTNR A ) POLYPEPTIDES, ANTIBODIES TO NTNR A AND COMPOSITION COMPRISING THE SAME פוליפפטידים לקולטן נוירטורין אנושי ) a ( NTNR,נוגדנים ל a NTNR ותכשירים המכילים אותם [31] [87] / [32] [33] US 08/ US 08/ US Int. Cl.8 A01K 067/027, A61K 038/18, 039/395, C07K 014/71, 016/28, 019/00, C12N 005/10, 015/12, 015/85, G01N 033/53, 033/68 GENENTECH, INC., WO/1998/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] An isolated polypeptide comprising a sequence selected from the group consisting of: (a) a human neurturin receptor-α (NTNRα) extracellular domain (ECD) amino acid sequence having the amino acid sequence set out in SEQ ID NO:3 between amino acid residues 23 and 447 inclusive; (b) an allelic variant or mammalian homolog of (a) having at least a 60% amino acid sequence identity with the NTNRα amino acid sequence set out in SEQ ID NO:3; (c) a sequence encoded by nucleic acid which hybridizes under stringent conditions (42 o C in 20% formamide) to a nucleic acid encoding (a) or (b), the sequence having the biological activity of binding neurturin (NTN); (d) a sequence derived from (a) by substitution, deletion, or addition of one or several amino acids in the amino acid sequence of (a), the sequence having at least 60% sequence identity with the NTNRα amino acid sequence set out in SEQ ID NO:3; and, (e) a sequence encoding at least 20 contiguous amino acids from (a). 2619

118 AGONISTS SPECIFIC FOR THE PERIPHERAL CANNABINOID RECEPTOR אגוניסטים ספציפיים לקולטנים הקנבינואידיים הפריפרליים [72] Int. Cl.8 A61K 031/09, 031/216, A61P 009/12, C07C 043/23 YISSUM RESEARCH יישום חברה לפיתוח המחקר של האוניברסיטה העברית בירושלים, ירושלים DEVELOPMENT COMPANY OF THE HEBREW UNIVERSITY OF אהרון גרזון JERUSALEM AARON GARZON רפאל משולם, אסתר פריד, לומיר הנוס, RAPHAEL MECHOULAM, ESTER אביבה ברוייאר, סוסנה צ'יליבון, מיכל FRIDE, LUMIR HANUS, AVIVA BREUER, SUSANA TCHILIBON, הורוביץ MICHAL HOROWITZ WEBB & ASSOCIATES, 2 PEKERIS ST., P.O.B. 2189, REHOVOT ד"ר וב ושות', רח' פקריס, 2 ת.ד. 2189, רחובות [57] A pharmaceutical composition of matter for treating or preventing hypertension, inflammation, peripheral pain or gastrointestinal disorders, comprising as an active ingredient a compound of the formula having the (3S, 4S) configuration, and which is essentially free of the (3R, 4R) enantiomer, wherein A---B designates an optional double bond, R 1 designates a variety of organic moieties, G designates hydrogen, halogen or various ether groups, and R 3 designates various alkyl groups, ether groups, or combinations thereof. 2620

119 IMIDAZOLYL-CYCLIC ACETALS, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM אסטלים אימידזוליל סיקליק, הכנתם, והרכבים פרמצבטיים שמכילים אותם [31] [87] [32] / / Int. Cl.8 C07D 405/00 RHONE-POULENC RORER LIMITED, UNITED KINGDOM WO/1998/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] GB US GB US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A compound of the formula wherein: R 1 is heteroaryl optionally substituted by one or more heteroaryl group substituents; R 2 is aryl optionally substituted by one or more aryl group substituents or R 2 is heteroaryl optionally substituted by one or more heteroaryl group substituents; R 3 represents a group L 1 -R 7 or L 2 -R 8 [where L 1 represents a straight-or branched-chain alkylene linkage containing from 1 to about 6 carbon atoms optionally substituted by halogen or oxo; R 7 is hydrogen, aryl, cyano, cycloalkyl, heteroaryl, heterocycloalkyl, nitro, - S(O) n R 9, (where R 9 is alkyl, aryl, arylalkyl, cycloalkyl, heteroaryl, heteroarylalkyl, or 2621 heterocycloalkyl and n is zero or an integer 1 or 2), -NHSO 2 R 9, -C(=Z)OR 10 (where Z is an oxygen or sulphur atom and R 10 is hydrogen or R 9 ), -C(=Z)R 10, -N(R 11 )- C(=Z)R 9 (where R 11 is hydrogen or alkyl), -NY 1 Y 2 {where Y 1 and Y 2 are independently hydrogen, alkenyl, alkyl, alkynyl, aryl, arylalkyl, cycloalkenyl cycloalkyl, heteroaryl or heteroarylalkyl, or the group NY 1 Y 2 may form a 5-7 membered cyclic amine which may optionally contain a further heteroatom selected from O, S, or NY 3 (where Y 3 is hydrogen, alkyl, aryl, arylalkyl, -CHO, - C(=Z)R 9 or SO 2 R 9 ), or which may also be fused to additional aryl, heteroaryl,

120 heterocycloalkyl or cycloalkyl rings to form a bicyclic or tricyclic ring system}, - SO 2 -NY 1 Y 2, -C(=Z)-NY 1 Y 2, -N(R 11 )- C(=Z) -NY 1 Y 2, -N(OR 10 ) C(=Z) -NY 1 Y 2, -N(OR 10 )-C(=Z)R 10, -C(=NOR 10 )R 10, - C(=Z)NR 10 OR 12 (where R 12 is hydrogen, alkyl, aryl or arylalkyl), -N(R 11 )-C(=NR 13 ) -NY 1 Y 2 (where R 13 is hydrogen, cyano, alkyl, cycloalkyl or aryl), or N(R 11 )- C(=Z)OR 11 ; L 2 represents a direct bond or a straight or branched-carbon chain comprising from 2 to about 6 carbon atoms and contains a double or triple carboncarbon bond; and R 8 is hydrogen, aryl, cycloalkenyl, cycloalkyl, heteroaryl or heterocycloalkyl]; R 4 represents a group L 3 -R 14 [where L 3 represents a direct bond or a straight-or branched-chain alkylene linkage containing from 1 to about 6 carbon atoms (optionally substituted by halogen, hydroxy, alkoxy or oxo); and R 14 is hydrogen, alkyl, azido, hydroxy, alkoxy, aryl, arylalkyloxy, aryloxy, carboxy (or an acid bioisostere), cycloalkyloxy, heteroaryl, heteroarylalkyloxy, heteroaryloxy, heterocycloalkyl, heterocycloalkyloxy, nitro, -NY 4 Y 5, {where Y 4 and Y 5 are independently hydrogen, aryl, cycloalkyl, heterocycloalkyl, heteroaryl or alkyl optionally substituted by alkoxy, aryl, cyano, cycloalkyl, heteroaryl, heterocycloalkyl, hydroxy, oxo-co 2 R 10, - CONY 1 Y 2 or -NY 1 Y 2, or the group NY 4 Y 5 may form a 5-7 membered cyclic amine which (i) may be optionally substituted with one or more substitutents selected from alkoxy, carboxamido, carboxy, hydroxy, oxo (or a 5, 6 or 7 membered cyclic acetal derivative thereof), R 9 or alkyl substituted by carboxy, carboxamido or hydroxy (ii) may also contain a further heteroatom selected from O, S, SO 2 or NY 6 (where Y 6 is hydrogen, alkyl, aryl, arylalkyl, -C(=Z)R 9, - C(=Z)OR 9 or SO 2 R 9 ) and (iii) may also be fused to additional aryl, heteroaryl, heterocycloalkyl or cycloalkyl ring to form a bicyclic or tricyclic ring system), - N(R 10 )-C(=Z)-R 15 (where R 15 is alkyl, alkoxy, aryl, arylalkyloxy, cycloalkyl, heteroaryl, heteroarylalkoxy or heterocycloalkyl); -N(R 10 )-C(=Z)-L 4 -R 16 (where R 16 is alkoxy, aryl, arylalkyloxy, arylalkyloxycarbonylamino, carboxy (or an acid bioisostere), cycloalkyl, cyano, halo, heteroaryl, heteroarylalkoxy, heterocycloalkyl, hydroxy or -NY 1 Y 2, and L 4 is a straight- or branched-chain alkylene linkage containing from 1 to about 6 carbon atoms), -NR-C(=Z)-NH-R 15, -NH- C(=Z)-NH-L 4 -R 16, -N(R 10 )-SO 2 -R 15, - N(R 10 )-SO 2 -L 4 -R 16, -S(O) n R 9, -C(=Z) NY 4 Y 5 or C(=Z)-OR 9 ]; R 5 represents hydrogen, alkyl or hydroxyalkyl; or R 4 and R 5, when attached to the same carbon atom, may form with the said carbon atom a cycloalkyl, cycloalkenyl or heterocycloalkyl ring or a group C=CH 2 ; R 6 represents hydrogen or alkyl; and m is zero or an integer 1 or 2; and wherein "heteroaryl group substituent" is a substituent selected from the group consisting of acyl, acylamino, alkoxycarbonyl, alkylenedioxy, aroyl, aroylamino, aryl, arylalkyloxycarbonyl, aryloxycarbonyl, carboxy, cyano, halo, heteroaroyl, heteroaryl, heteroaroylamino, hydroxy, nitro, trifluoromethyl, R 17 Z 3-, Y 4 Y 5 N -, Y 4 Y 5 N-CO-, Y 4 Y 5 NSO 2 -, alkyl SO 2 -Y 4 N - or alkyl optionally substituted with aryl, heteroaryl, hydroxy, oxo, - CO 2 R 10, -CONY 1 Y 2 and Y 4 Y 5 N-;and "aryl group substituent" is a substituent selected from the group consisting of acyl, acylamino, alkoxy, alkoxycarbonyl, alkylenedioxy, alkylsulphinyl, alkylsulphonyl, alkylthio, aroyl, aroylamino, aryl, arylalkyloxy, arylalkyloxycarbonyl, arylalkylthio, aryloxy, aryloxycarbonyl, arylsulphinyl, arylsulphonyl, arylthio, carboxy, cyano, halo, heteroaroyl, heteroaryl, heteroarylalkyloxy, heteroaroylamino, 2622

121 heteroaryloxy, hydroxy, nitro, trifluoromethyl, Y 7 Y 8 N-, -Y 7 Y 8 NCO-, Y 7 Y 8 NSO 2 -(wherein Y 7 and Y 8 are independently hydrogen, alkyl, aryl, arylalkyl, heteroaryl, and heteroarylalkyl), Y 7 Y 8 N-C 2-6 alkylene-z 2 -(wherein Z 2 is O, NR 5 or S(O) n ), alkyl C(=O)-Y 7 N-, alkyl SO 2 -Y 7 N- or alkyl optionally substituted with aryl, heteroaryl, hydroxy, and Y 7 Y 8 N-;and N-oxides thereof, and their ester prodrugs; and pharmaceutically acceptable salts and solvates (e.g. hydrate of compounds of formula (l) and N-oxides thereof, and their ester prodrugs. HOLLOW FIBER CO-FLOW FILTRATION DEVICE מתקן מסיבים חלולים לסינון בזרימה מקבילה [31] [87] / [32] Int. Cl.8 B01D 063/02, 063/10, 069/10 GENENTECH, INC., U.S.A. WO/1999/ S. HOROWITZ & CO., ZION HOUSE, ROTHSCHILD BLVD., TEL AVIV [33] US 41-45, תל, ש. הורוביץ ושות', בית ציון, שדרות רוטשילד אביב [57] A hollow fiber membrane filtration module useful for separating species of interest from a mixture, said filtration module comprising: (a) a filter cartridge shell; and (b) a hollow fiber filter element contained within said filter cartridge shell, said hollow fiber filter element comprising a mat of hollow fibers physically layered onto the surface of a flow-restricting screen, wherein the hollow fibers of said filter element are configured into a bundle and said flow-restricting screen occupies at least 5% of the void volume between said hollow fibers such that the flow of filtrate between said hollow fibers is restricted and the transmembrane pressure is substantially constant along the entire length of the hollow fibers in said module. 2623

122 PHARMACEUTICAL ANTI- NOCICEPTIVE ANALGESIC COMPOSITION COMPRISING NORIBOGAINE תכשיר רוקחי אנאלגזי נגד תופעות כאב הכולל נוריבוגיין [31] [87] / [32] [33] US Int. Cl.8 A61K 031/55, A61P 025/00, C07D 471/18 NOVONEURON INC., U.S.A. WO/1999/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Use of an effective amount of noribogaine or its salt for the manufacture of a pharmaceutical composition for the alleviation or elimination of nociceptive pain in a patient in the absence of chemical dependence or drug abuse, substantially as described in the specification. SEEDLESS TOMATOES AND METHODS FOR MAKING THE SAME עגבניות ללא גרעינים ושיטות להכנתן [31] [87] / [32] Int. Cl.8 A01H 001/00, 001/04, 005/00 SEMINIS VEGETABLE SEEDS, INC., U.S.A. WO/1999/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] US וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים [57] A process for producing a hybrid Lycopersicon esculentum plant which produces fruit which is 100% seedless the process comprising the steps of: (a) selecting a Lycopersicon esculentum plant containing at least one parthenocarpic gene; (b) selecting a Lycopersicon esculentum plant which is cytoplasmically male sterile and contains at least one parthenocarpic gene; and (c) crossing the plants identified in steps (a) and (b); wherein parent plants identified in steps (a) and (b) are 2624

123 homozygous for the parthenocarpic gene(s), and wherein said gene(s) are identical. [31] [87] ADENOVIRUS VECTORS AND METHOD FOR REDUCING THE FREQUENCY OF INTRA- OR INTERMOLECULAR HOMOLOGOUS RECOMBINATION BETWEEN CHROMOSOMAL AND EXTRA- CHROMOSOMAL NUCLEIC ACID /14383 [32] Int. Cl.8 C12N 005/10, 015/861 AVENTIS PHARMA S.A., FRANCE WO/1999/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA ווקטורים אדנ וויראליים ושיטה להפחתת תדירות רקומבינציה הומולוגית בין או תוך מולקולרית, בין חומצות גרעין כרומוזומליות לבין חומצות גרעין חוץ כרומוזומליות [33] FR לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] A method for reducing the frequency of intra-or intermolecular homologous recombination events between a chromosomal nucleic acid comprising the E1 region of an adenovirus genome, as well as a flanking region, and an extrachromosomal nucleic acid which comprises an adenovirus genome defective for the E1 region, wherein said method comprises introducing into the cell comprising said chromosomal nucleic acid, said extrachromosomal nucleic acid, wherein the sequence of at least one of the two nucleic acids is a coding sequence and is degenerated. 2625

124 CRYSTALLINE FORMS OF HYDRATED 1S-[ALPHA (2S*,3R*) 9ALPHA]- 6,10 DIOXO N (2 ETHOXY 5 OXO TETRAHYDRO 3 FURANYL) - 9[[(1-ISOQUINOLYL) CARBONYL]- AMINO] OCTAHYDRO 6H PYRIDAZINO [1, 2 A] [1,2] DIAZEPIN 1 CARBOXAMIDE צורות גבישיות של של הידראטים S1 1] אלפא,(R*,2S3*) 9 אלפא],6 10 דיאוקסו N 2) אתוקסי 5 אוקסו טטראהידרו 3 פורניל) 9 1)]] איזוקינוליל) קרבוניל] אמינו] אוקטאהידרו H6 פירידזינו 2,1] [A [2,1] דיאזפין 1 קרבוקסאמיד [31] [72] [87] /04367 [32] Int. Cl.8 A61K 038/06, C07K 005/023 AVENTIS PHARMA S.A., FRANCE JEAN-YVES GODARD, VALERIE ROGNON WO/1999/ EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] FR איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] Crystalline form of anhydrous 1S- [1α(2S*, 3R*), 9α]-6, 10-dioxo-N-(2- ethoxy-5-oxo-tetrahydro-3-furanyl)-9-[[(1- isoquinolyl) carbonyl]amino]-octahydro- 6H-pyridazino[1,2-a] [1,2] diazepine-1- carboxamide. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2626

125 MECHANISM FOR MATCHING A RECEIVER WITH A SECURITY MODULE מנגנון להתאמת מקלט עם מודולת אבטחה [31] [87] PCT/IB98/00681 [32] Int. Cl.8 H04N 007/16, 007/167 NAGRACARD S.A., SWITZERLAND WO/1999/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] WO וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים [57] A pay-tv reception system comprising a receiver connected to security means, this receiver receiving descrambling information from the security means, characterized in that at least a part of the information is encrypted, before being transmitted to the receiver by said security means, with a unique encryption key stored on the one hand in the receiver and, on the other hand, in the security means, said encryption key forming a matching between the security means and the receiver, the system further comprising a verification mechanism of the conformity of said matching. 2627

126 [31] [87] COMPACT FINGERPRINT OPTICAL SENSOR /06090 [32] Int. Cl.8 G06K 009/00 SAGEM DEFENSE SECURITE, FRANCE WO/1999/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV חיישן אופטי קומפקטי לטביעת אצבעות [33] FR ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] Optical fingerprint sensor including an optical transmission body (1) having a reception surface (8) intended to receive a finger (100), an image of whose fingerprint is to be taken, illumination means (3) for the finger, imaging means (2) having a detection surface (4) for imaging the finger through the optical transmission body and thus sensing the fingerprint according to imaging angles corresponding to the incidences of light rays of the illumination means, directed onto the reception surface with total reflection onto the grooves of the fingerprint of the finger, the sensor being characterised by the fact that the optical transmission body comprises a surface (11) for determining the magnification between the fingerprint and its image, arranged in order to direct the light rays of the illumination means towards the fingerprint and in order to modify the optical paths of the light rays coming from the illumination means so that the light rays, which are reflected onto the grooves of the fingerprint of the finger, strike the detection surface of the imaging means, leaving the body without encountering an optical element. 2628

127 FLUOROPHENYL RESIN COMPOUNDS AND PROCESS FOR THEIR PREPARATION תרכובות שרף פלוארו פניל ותהליך להכנה [31] [87] / [32] Int. Cl.8 C08F 212/06, 212/36 AVENTIS PHARMACEUTICALS INC., U.S.A. WO/1999/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A fluorophenyl resin compound of the formula wherein s is a solid support; A is selected from L is a chemical bond, 2629

128 m is 1 to 5; p is 0, 1, or 2; B is F, OW, or azaheterocyclenyl; R i is CH 2 R f, R 0, R 1 and SO2Z; D is CH or N; W is hydrogen, R 2 are a ring system substituent, or R 0 and tripyrrolidinophosphonium, C(O)V, R 1 taken together with the adjacent carbon C(O)R a, C(O)NR b R c, C(O)OR a or SO 2 R a atoms through which they are linked form V is Cl or imidazol-l-yl; Y is O or NR 3 ; Z a 6 membered aryl or 5 to 6 membered is Cl, -OH, OR a or NR a R i ; R a and R f are heteroaryl; R 3 is H or lower alkyl; and R 4, independently aliphatic or aromatic; R b R 5, R 6 and R 7 are independently ring and R c are independently H, aliphatic or system substituents, or R 4 and R 5 taken aromatic, or R b and R c, taken together with together with the carbon atoms through the N atom through which they are which they are linked form a 6 membered attached, form an azaheterocyclyl or aryl or 5 to 6 membered heteroaryl. USE OF FARNESYL PROTEIN TRANSFERASE INHIBITOR FOR THE PREPARATION OF A PHARMACEUTICAL COMPOSITION HAVING RADIOSENSITIZING PROPERTIES שימוש במעכב חלבון פרנזיל טרנזיל טרנספרז להכנת תכשיר רוקחי בעל תכונות המגיברות רגישות לקרינה [31] [87] [32] [33] EP EP Int. Cl.8 A61K 031/47, A61P 035/00, 043/00, C07D 401/10, 401/14, 405/14, 413/14 JANSSEN PHARMACEUTICA N.V., BELGIUM WO/2000/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Use of at least one farnesyl protein transferase inhibitor for the preparation of a pharmaceutical composition having radiosensitizing properties for administration before, during or after irradiation of a tumor for treating cancer in vivo, wherein the said farnesyl protein transferase inhibitor is a compound of formula (I), or a compound of formula (II) or (III) which is metabolized in vivo to a 2630

129 compound of formula (I), said compounds being represented by a stereoisomeric form thereof, a pharmaceutically acceptable acid or base addition salt thereof, wherein the dotted line represents an optional bond and X, R 1 - R 19, Alk 1, Ar 1, Ar 2, are as defined in the specification SYNTHETIC PEPTIDES FOR DIAGNOSIS AND TREATMENT OF ANTIPHOSPHOLIPID SYNDROME פפטידים סינתטיים לאבחון וטיפול בסינדרום אנטי פוספוליפיד [31] [72] [87] [32] [33] IL Int. Cl.8 A61P 043/00, C07K 007/06, 014/775, 017/02 YEDA RESEARCH AND ידע חברה למחקר ופיתוח בע"מ, רחובות DEVELOPMENT CO. LTD. CABILLY, MIRI BLANK, SHMUEL מירי בלנק, שמואל קבילי, יהודה שיינפלד YEHUDA SHOENFELD AND EPHRAIM KATCHALSKI-KATZIR ואפריים קצ'לסקי-קציר WO/2000/ PAULINA BEN-AMI, BEN-AMI & פאולינה בן-עמי, בן עמי ושות', ASSOCIATES, P.O.B. 94, ת.ד. 94, רחובות REHOVOT [57] A synthetic peptide selected from the group consisting (i) a peptide of SEQ ID NO:1 to SEQ ID NO:7, of the sequences; 2631 Leu Lys Thr Pro Arg Val (SEQ ID NO:1); Lys Thr- Pro Arg- Val Thr (SEQ ID NO:2);

130 Asn- Thr Leu Lys Thr Pro Arg Thr- Lys Leu Arg- Val Tyr (SEQ ID Val Gly Gly (SEQ ID NO:3); NO:6); and Lys Asp Lys Ala Thr Phe Gly- Cys Ala Thr Leu Arg Val Tyr Thr His Asp Gly (SEQ ID NO:4); Lys Gly Gly (SEQ ID NO: 7); and (ii) a peptide of (i) that is biotinylated. AZETIDINE DERIVATIVES, THEIR PREPARATION AND MEDICINES CONTAINING THEM נגזרות של אזטידין, הכנתן ותרופות המכילות אותן [31] [87] /11342 [32] [33] FR 60/ US Int. Cl.8 A61P 001/00, 003/04, 009/00, 011/06, 025/30, 037/00, C07D 205/06, 401/06, 401/12, 403/12, 405/12, 409/06, 413/12, 417/06 AVENTIS PHARMA S.A., FRANCE WO/2000/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] Compounds of the formula: in which R represents a chain R1 represents a methyl or a ethyl radical, alkyl, alkoxy CO-alk, hydroxyl, -COOR 5, R 2 represents either an aromatic chosen formyl, trifluoromethyl, from phenyl, naphthyl or indenyl, these trifluoromethylsulphanyl, aromatics being nonsubstituted or trifluoromethoxy, nitro, - NR 6 R 7, -CO-NHsubstituted with one or more halogen, NR 6 -R 7, -N(alk)COOR 8, cyano,

131 CONHR 9, -CO-NR 16 R 17, alkylsulphanyl, hydroxyalkyl O-alk-NR 12 R 13 or alkylthioalkyl or a heteroaromatic chosen from the benzofuryl, benzothiazolyl, benzothienyl, benzoxazolyl, chromanyl, 2, 3-dihydrobenzofuryl, 2, 3- dihydrobenzothienyl, indolinyl, indolyl, isochromanyl, isoquinolyl, pyridyl, quinolyl, 1, 2, 3, 4-tetrahydroisoquinolyl, 1, 2, 3, 4-tetrahydroquinolyl, thiazolyl, or thienyl, rings, it being possible for these heteroaromatics to be nonsubstituted or substituted whith a halogen, alkyl, alkoxy, -COOR 5, trifluoromethyl, trifluoromethylsulphanyl, trifluoromethoxy, nitro, -NR 6 R 7, -CO-NH- NR 6 R 7, cyano, -CONHR 9, alkylsulphanyl, hydroxyalkyl or alkylthioalkyl, R 3 and R 4, which are identical or different, represent either an aromatic chosen from phenyl, naphthyl or indenyl, these aromatics being nonsubstituted or substituted with one or more halogen, alkyl, alkoxy, formyl, hydroxyl, trifluoromethyl, trifluoromethoxy, -CO-alk, cyano, - COOR 5, -CONR 10 R 11, -CO-NH-NR 6 R 7, alkylsulphanyl, hydroxyalkyl, -alk-nr 6 R 7 or alkylthioalkyl; or a heteroaromatic chosen from benzofuryl, benzothiazolyl, benzothienyl, benzoxazolyl, chromanyl, 2, 3-dihydrobenzofuryl, 2, 3- dihydrobenzothienyl, furyl, isochromanyl, isoquinolyl, pyrrolyl, quinolyl, 1, 2, 3, 4- tetrahydroisoquinolyl, thiazolyl or thienyl rings, it being possible for these heteroaromatics to be nonsubstituted or substituted with a halogen, alkyl, alkoxy, hydroxyl, trifluoromethyl, trifluoromethoxy, cyano, -COOR 5, -CO- NH-NR 6 R 7, - CONR 10 R 11, -alk-nr 6 R 7, alkylsulphanyl, hydroxyalkyl or alkylthioalkyl, R 5 is an alkyl or phenyl radical which is optionally substituted with one or more halogen atoms, R 6 and R 7, which are identical or different, represent a hydrogen atom or an alkyl, -COOalk, cycloalkyl, alkylcycloalkyl, -alk-o-alk or hydroxyalkyl radical or alternatively R and R 7 together form with the nitrogen atom to which they are attached a 3-to 10- membered saturated or unsaturated monoor bicyclic heterocycle optionally containing another heteroatom chosen from oxygen, sulphur and nitrogen and being optionally substituted with one or more alkyl, -COalk, -COOalk, -CO- NHalk, -CS- NHalk, -CO-alk-NR 14 R 15, oxo, hydroxyalkyl, -alk-o-alk or CO-NH 2 radicals, R 8 represents an alkyl radical, R 9 represents a hydrogen atom or an alkyl radical or an alkyl radical substituted with dialkylamino, phenyl, cycloalkyl, (optionally substituted with COOalk) or a 3- to 10-membered saturated or unsaturated mono- or bicyclic heterocycle containing one or more heteroatoms chosen from oxygen, sulphur and nitrogen and being optionally substituted with one or more alkyl radicals, R 10 and R 11, which are identical or different, represent a hydrogen atom or an alkyl radical or alternatively R 10 and R 11 together form with the nitrogen atom to which they are attached a 3- to 10-membered saturated mono-or bicyclic heterocycle optionally containing another heteroatom chosen from oxygen, sulphur and nitrogen and being optionally substituted with an alkyl radical, R 12 and R 13, which are identical or different, represents a hydrogen atom or an alkyl or cycloalkyl radical or alternatively R 12 and R 13 together form with the nitrogen atom to which they are attached a 3- to 10-membered saturated mono-or bicyclic heterocycle optionally containing another heteroatom chosen form oxygen, sulphur and nitrogen and being optionally substituted with an alkyl, -COalk, - COOalk, -CO-NHalk, -CS- NHalk or COalk-NR 14 R 15 radical or a 3- to 10- membered saturated mono-or bicyclic heterocycle containing a heteroatom chosen from oxygen, sulphur and nitrogen, R 14 and R 15, which are identical or different, represent a hydrogen atom or an alkyl or COOalkyl radical, R 16 and R 17

132 together form with the nitrogen atom to which they are attached a 3- to 10- membered saturated mono- or bicyclic heterocycle optionally containing another heteroatom chosen from oxygen, sulphur and nitrogen, R' represents a hydrogen atom or a CO-alk radical, alk represents an alkyl or alkylene radical, it being understood that the alkyl and alkylene radicals and portions and the alkoxy radicals and portions are in the form of a straight or branched chain and contain 1 to 6 carbon atoms, their optical isomers and their salts with an inorganic or organic acid AGLYCO PRODUCTS AND USES THEREOF מוצרי אגליקו והשימוש בהם [31] [87] / [32] [33] US Int. Cl.8 A61K 031/7008, 038/10, A61P 031/18, 035/00, C07K 007/08, G01N 033/53 SAMUEL BOGOCH, U.S.A. ELENORE S. BOGOCH, U.S.A. WO/2000/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] An isolated peptide having the amino acid sequence of SEQ ID NO:1, or SEQ ID NO: 2, or both. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2634

133 PROCESS FOR THE PREPARATION OF ALKYL MERCAPTO METHYL ERGOLINE DERIVATIVES AND SOME NOVEL INTERMEDIATES OBTAINED THEREWITH תהליך להכנת נגזרות של אלקיל מרקפטו מתיל ארגולין ומספר תרכובות ביניים חדשות המתקבלות במהלכו [31] [87] MI99A [32] [33] IT Int. Cl.8 A61P 025/16, C07D 457/02, C12P 017/18 POLI INDUSTRIA CHIMICA SPA, ITALY WO/2000/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A process for the preparation of a compound of the formula wherein R 4 is a saturated or unsaturated C 1-8 alkyl radical, comprising the following steps: (a) a compound of the formula 2635

134 wherein R 1 represents a saturated or unsaturated C 1-8 alkyl residue, is reacted with 3-halo- and/or 2-halo-propionyl chloride in an aprotic organic solvent in the presence of a proton acceptor; (b) the compound or mixture of compounds so obtained in step (a) is then reacted with calcium borohydride in tetrahydrofuran at a temperature between 10 and 65 o C; (c) the compound so obtained in step (b) is reacted in an aprotic organic solvent with an alkylsulphonyl chloride in the presence of a proton acceptor; (d) the compound so obtained in step (c) is then reacted in an aprotic organic solvent with a compound of formula R 4 SX, wherein R 4 has the meaning given above and X is an alkali metal; (e) the compound so obtained in step (d) is converted into compound VI by treatment with a reducing agent in an aprotic organic solvent. Also claimed as new are compounds of the formula wherein R 2 and R 3 are halogen and hydrogen, respectively, or are bonded to one another by a double bond and R 1 represents a saturated or unsaturated C 1-8 alkyl residue; 2636

135 wherein X is a halogen or a compound of the general formula R 5 SO 3 - and R 5 is selected from methyl, ethyl, p-tolyl and wherein R 4 is saturated or unsaturated C 1-4 alkyl residue. This specification was examined in accordance with regulation 35 of the Patent Regulations, פירוט זה נבחן בהתאם לתקנה 35 לתקנות הפטנטים, תשכ"ח

136 USE OF A PRO172 POLYPEPTIDE IN THE PREPARATION OF PHARMACEUTICAL COMPOSITIONS FOR INHIBITING NEOPLASTIC CELL GROWTH שימוש בפוליפפטיד PRO172 להכנת תכשירים רוקחיים לעיכוב הגידול של תאים ניאופלסטיים [31] [87] / [32] [33] US Int. Cl.8 A61K 038/17, A61P 043/00, C07K 014/47, C12N 015/12, 015/62 GENENTECH, INC., U.S.A., WO/2000/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Use of a PRO 172 polypeptide in the preparation of a pharmaceutical composition for inhibiting the growth of a tumor cell, wherein said PRO 172 polypeptide comprises at least about 80% amino acid sequence identity to (a) residues 1 or 22 to 723 of the PRO 172 polypeptide shown in Figure 8 as shown in the specification (SEQ ID NO:21), (b) X to 723 of the PRO 172 polypeptide shown in Figure 8 (SEQ ID NO:21), wherein X is any amino acid residue from 17 to 26 of Figure 8 (SEQ ID NO:21) or (c) 1 or 22 to X of Figure 8 (SEQ ID NO:21), wherein X is any amino acid from amino acid 543 to amino acid 552 of Figure 8 (SEQ ID NO:21). The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2638

137 PROTEIN HAVING TOXIN ACTIVITY AGAINST A COLEOPTERAN INSECT, A POLYNUCLEOTIDE ENCODING THE PROTEIN AND METHODS USING THE PROTEIN חלבון בעל פעילות רעלן נגד חרק קשי כנפיים, פולינוקליוטיד המקודד לחלבון ושיטות המשתמשות בחלבון [31] [87] / [32] [33] US Int. Cl.8 A01N 063/00, C07K 014/325, C12N 001/21, 015/32, 015/82, C12R 001/07 MYCOGEN CORPORATION, U.S.A. WO/2001/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] An isolated polynucleotide that encodes a protein having toxin activity against a coleopteran insect, wherein the complement of said polynucleotide hybridizes under stringent conditions with a nucleotide sequence selected from the group consisting of SEQ ID NO:46, SEQ ID NO:47, SEQ ID NO:48, SEQ ID NO:49, SEQ ID NO:50, SEQ ID NO:51, SEQ ID NO: 53, SEQ ID NO:55, SEQ ID NO:57, SEQ ID NO:59, SEQ ID NO:61, SEQ ID NO:63, SEQ ID NO: 65, SEQ ID NO:67, SEQ ID NO:69, SEQ ID NO:71, SEQ ID NO:73, SEQ ID NO:75, SEQ ID NO: 77, SEQ ID NO:79, SEQ ID NO:81, SEQ ID NO:83, SEQ ID NO:85, SEQ ID NO:87, SEQ ID NO: 89, SEQ ID NO:91, SEQ ID NO:93, SEQ ID NO:95, SEQ ID NO:97, SEQ ID NO:99, SEQ ID NO: 101 SEQ ID NO:103, SEQ ID NO:105, SEQ ID NO:107, SEQ ID NO:109, SEQ ID NO:111, SEQ ID NO:113, SEQ ID NO:115, SEQ ID NO:117, SEQ ID NO: 119, SEQ ID NO:121, SEQ ID NO:123, SEQ ID NO:125, SEQ ID NO:131, SEQ ID NO:132, SEQ ID NO:133, SEQ ID NO:135, SEQ ID NO: 137, SEQ ID NO: 139, SEQ ID NO: 141, SEQ ID NO: 143, SEQ ID NO: 145, SEQ ID NO: 147, SEQ ID NO: 149, SEQ ID NO; 151, SEQ ID NO: 153, SEQ ID NO: 155, SEQ ID NO: 156, SEQ ID NO: 157, SEQ ID NO: 158, SEQ ID NO: 160, SEQ ID NO: 161, SEQ ID NO: 162, SEQ ID NO: 163, SEQ ID NO: 164, SEQ ID NO: 165 and SEQ ID NO:

138 BIOCOMPATIBLE, BIODEGRADABLE, WATER- ABSORBENT MATERIAL AND METHODS FOR ITS PREPARATION חומר מתאים לחומר מן החי, מתכלה וסופג מים ושיטות להכנתו Int. Cl.8 A61F 013/00, A61K 047/00, A61L 015/22, C08F 210/00, 210/02, 218/00, 220/00, C08J 003/24, C08L 001/00, 003/00, 005/00, C09K 017/18 EXOTECH BIO SOLUTION LTD. אקסוטק ביו סולושין בע"מ, קרית גת SELIGSOHN GABRIELI & CO., זליגסון גבריאלי ושות', 31 YAVNE ST., רח' יבנה, 31 ת.ד. 1426, תל אביב P.O.B. 1426, TEL AVIV [57] A bio-compatible, biodegradable macromolecular water-absorbent polymeric matrial having a threedimensional configuration with intermolecular covalent bonds and containing free functional groups selected from OH, SH, NH 2, and COOH, said polymer being formed by polymerpolymer inter-coupling interaction between a natural water-soluble polymer A or its derivatives having a molecular weight between 20,000 and 500,000 Da, and a synthetic polymer B in a ratio of A:B of 15:85 to 85:15, wherein the natural watersoluble polymer A is selected from the group consisting of: (A1) a non-ionic natural, partially denatured or chemically modified polymer, that does not dissociate in water and which can undergo polymer-polymer intercoupling reactions, having only free hydroxyl groups in an amount of at least 5x10-3 moles OH/g, and optionally containing non-ionic groups, (A2) an anionic natural, partially denatured or chemically modified polymer, that dissociates in water to form anions and which can undergo polymer-polymer intercoupling reactions, said polymer optionally containing non-ionic groups, (A3) a cationic natural, partially denatured or chemically modified polymer, that dissociates in water to form cations and which can undergo polymer-polymer intercoupling reactions, said polymers optionally containing non-ionic groups, (A4) an amphoteric natural, partially denatured or chemically modified polymer, that dissociates in water to form both anions and cations and which can undergo polymer-polymer intercoupling reactions, and (A5) mixtures of A1-A4, polymer A being capable of undergoing polymer-polymer intercoupling, and wherein: the synthetic polymer B is a linear or branched reactive synthetic copolymer having a molecular weight of 10, ,000 Da derived from a vinyl monomer and an ethylenically unsaturated monomer, said copolymer having a backbone with polymeric subunits R n and R r wherein R represents a subunit covalently bonded to the polymer backbone, n represents non-reactive chemical functional groups and r represents reactive chemical functional groups. 2640

139 METHOD FOR DIAGNOSING AND IMPROVING VISION שיטה לאיבחון ושיפור הראיה [31] [87] / [32] Int. Cl.8 A61B 017/32 SCIENTIFIC OPTICS, INC., U.S.A. WO/2000/ EITAN MEHULAL LAW GROUP, 10 ABBA EBEN BLVD., P.O. B. 2081, HERZLIYA [33] US קבוצת איתן מהולל, עורכי דין ועורכי פטנטים, שדרות אבא אבן, 10 ת.ד. 2081, הרצליה [57] A method for diagnosing, analyzing or planning the treatment of the cornea of an eye, said method being performed with the aid of a computer system running a topological modeling computer program which, making use of sampled points on the cornea for which the coordinates are known relative to a reference plane, produces a surface model of said cornea which closely represents the surface of the cornea, said method comprising the steps of: modifying the shape of the surface model enough to change the radius of curvature at a plurality of selected points to achieve a correction in vision indicated to be necessary by an eye test, without introducing substantial changes in shape that are not associated with changing the radius of curvature, to produce a corrected surface model; and at least one of: viewing the surface model or the corrected surface model on a display device; and utilizing the corrected surface model to produce information to control the laser ablation of the cornea. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2641

140 CONVERSATIONAL BROWSER AND CONVERSATIONAL SYSTEMS מעלעל דיבורי ומערכות דיבוריות [31] [87] / [32] [33] US 60/ US Int. Cl.8 G06F 003/16, 017/30, G10L 013/00, 015/00, H04M 003/487, 003/493, 003/50 LENOVO (SINGAPORE) PTE. LTD., SINGAPORE WO/2000/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] A conversational browsing system, comprising: a conversational browser comprising: a command and control interface for converting an input command; and a CML (conversational markup language) processor for parsing and interpreting a CML file, the CML file comprising meta-information representing a conversational user interface for presentation to a user; a conversational engine for decoding input commands for interpretation by the command and control interface and decoding meta-information provided by the CML processor for generating synthesized audio output; and a communication stack for transmitting the navigation request to a content server and receiving a CML file from the content server based on the navigation request. 2642

141 REPLICATION DEFICIENT BACULOVIRUS EXPRESSION SYSTEM מערכת ביטוי בקיולוירוס נטולת רפליקציה [31] [87] [32] [33] GB Int. Cl.8 C12N 001/19, 001/21, 005/10, 015/81, 015/866 NATURAL ENVIRONMENT RESEARCH COUNCIL, UNITED KINGDOM OXFORD BROOKES UNIVERSITY, UNITED KINGDOM WO/2001/ EITAN, PEARL, LATZER AND איתן, פרל, לצר וכהן צדק, COHEN ZEDEK, P.O.B , רחוב שנקר, 7 ת.ד , הרצליה HERZLIYA [57] Method for cloning a gene (a) a nucleic acid sequence which is comprising the steps of: capable of restoring replication in the (i) providing a replication-deficient replication-deficient baculovirus vector; baculovirus vector capable of being and maintained in an intermediate cell, wherein (b) at least one gene to be cloned; the intermediate cell is a yeast cell or a (iii) allowing the replication-deficient bacterial cell, the replication deficient baculovirus vector and rescue vector to baculovirus vector comprising one or more recombine in an insect cell to produce a nucleic acid sequences which enable the replication-enabled baculovirus vector vector to replicate within the intermediate comprising the at least one gene to be host; cloned; and (ii) providing a rescue vector encoding: (iv) growing the replication-enabled baculovirus vector within the insect cell. 2643

142 SYSTEM AND METHOD FOR FREQUENCY UP-CONVERSION מערכת ושיטה להעלאת תדר [31] [87] / [32] / / / / Int. Cl.8 H03C 001/62 PARKERVISION, INC., U.S.A. WO/2000/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] US US US US US וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים [57] A method of up-converting, comprising: (1) gating a first reference signal under the control of a first modulated information signal to generate a first gated signal; and (2) isolating at least one harmonic of the first gated signal to generate a first upconverted information signal IMAGING DEVICE התקן הדמייה [31] [87] [32] [33] GB Int. Cl.8 G01T 001/24, H01L 027/14, H04N 003/15, 005/32 IPL INTELLECTUAL PROPERTY LICENSING LIMITED, CYPRUS WO/2000/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] An imaging device (6) for imaging radiation, the imaging device comprising an image cell array including an array of detector cells (11) for generating charge in response to incident radiation and a corresponding array of pixel circuits (12) comprising accumulation circuitry (53) for accumulating pixel image values corresponding to incident radiation on respective detector cells, each pixel circuit being associated with a respective detector cell, wherein said accumulation circuitry comprises counting circuitry for counting plural radiation hits incident on said associated detector cell, and said pixel image value comprises a count value of 2644

143 said hits, characterised in that: the imaging device is adapted for scan imaging radiation in a Time Delay Integration (TDI) mode, and each pixel circuit is controllable to transfer a pixel image value to an adjacent pixel circuit (49), said pixel circuit being operable to receive a pixel image value from an adjacent pixel circuit (48). USE OF AN ALIQUOT OF A MAMMAL'S BLOOD IN THE PREPARATION OF A MEDICAMENT FOR PREVENTING PROGRESSION OF ATHEROSCLEROSIS IN MAMMALS שימוש בקרטב של דם היונק בהכנת תרופה למניעת התקדמות של טרשת עורקים ביונקים [31] [87] / [32] / Int. Cl.8 A61K 035/14 VASOGEN IRELAND LIMITED, IRELAND WO/2000/ SELIGSOHN GABRIELI & CO., 31 YAVNE ST., P.O.B. 1426, TEL AVIV [33] US US זליגסון גבריאלי ושות', רח' יבנה, 31 ת.ד. 1426, תל אביב [57] Use in preparation of a medicament for preventing progression of 2645 atherosclerosis in a mammal, of an aliquot of the mammal's blood which has been

144 subjected extracorporeally to an environment. electromagnetic emission and an oxidative DEVICE AND METHOD FOR DEPLOYMENT OF A MESH IN LAPAROSCOPIC HERNIA REPAIR Int. Cl.8 A61B 017/00, 017/11 ELIAHU ANTEBI ELIAHU ANTEBI, 102 ROTSCHILD BLVD., TEL AVIV התקן ושיטה לפרישת רשת בניתוח לפרוסקופי של הרניה אליהו ענתבי, תל אביב אליהו ענתבי, שד' רוטשילד 102, תל אביב [57] A device for inserting and internally deploying a mesh and for positioning the mesh over a hernia defect in a laparoscopic hernia repair, comprising: (a) a hollow tubular capsule (2) having a proximal end and distal end; (b) a central rod (8) extending along the central longitudinal axis of said tubular capsule; (c) a folded mesh (12) located inside the capsule, having a releasable connection to said rod, wherein said mesh is built with a mesh frame so constructed as an inverted closed umbrella (22, 23) and said mesh is extendable, in a manner similar to that of an umbrella, to an open planar configuration when pushed out from the distal end of said capsule and extended; (d) extending means for both pushing the mesh out of the capsule and for opening the mesh to the open planar configuration. 2646

145 PALLADIUM-SUBSTITUTED BACTERIOCHLOROPHYLL DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM תולדות בקטריוכלורופיל המותמרות בפאלאדיום, הכנתן ותכשירי רוקחות המכילים אותן [31] [72] [87] [32] [33] EP Int. Cl.8 A61K 031/409, 038/38, A61P 035/00, C07D 487/22, C12P 017/18 YEDA RESEARCH AND ידע חברה למחקר ופיתוח בע"מ, רחובות DEVELOPMENT CO. LTD. YORAM SALOMON, HUGO SCHEER, ALEXANDER BRANDIS, AVIGDOR SCHERZ WO/2000/ PAULINA BEN-AMI, BEN-AMI & פאולינה בן-עמי, בן עמי ושות', ASSOCIATES, P.O.B. 94, ת.ד. 94, רחובות REHOVOT [57] A compound of the formulae 2647

146 2648

147 A represents OH, -O-R 1, -O-(CH 2 ) n -Y, -S-(CH 2 ) n -Y, -NH-(CH 2 ) n -Y, -O-(CH 2 ) 2 -OH, -NH-(CH 2 ) 2 -NH-BOC or -N-(CH 2 -CH=CH 2 ) 2 wherein R 1 represents Na +, K +, (Ca 2+ ) 0.5, (Mg 2+ ) 0.5, Li +, NH + 4, + NH 3 -C(CH 2 OH) 3, + NH 3 -CH 2 - (CHOH) 4 -CH 2 OH, + NH 2 (CH 3 )-CH 2 - (CHOH) 4 -CH 2 OH or + N(C n H 2n+1 ) 4 ; R 2 represents H, OH or COOR 4, wherein the compound is of formula I, wherein R 4 is C 1 -C 12 alkyl or C 3 -C 12 cycloalkyl, or R 2 represents H or C 1 -C 12 alkyl when the compound is of formula I'; R 3 represents H, OH or C 1 -C 12 alkyl or alkoxy when the compound is of formula l, or R 3 represents H or C 1 -C 12 alkyl when the compound is of formula l'; n is 1, 2, 3, 4, 5 or 6, Y is NR' 1 R' 2 or - + NR' 1 R' 2 R' 3, X - wherein R' 1, R' 2 and R' 3 independently from each other represent CH 3 or C 2 H 5 ; X is F, Cl, Br or I, N' is 1, 2, 3 or 4, and wherein * denotes an asymmetric carbon and --- represents a single saturated bond or a double unsaturated bond [31] [72] [87] DISPERSIBLE CONCENTRATE FOR THE DELIVERY OF CYCLOSPORIN / [32] Int. Cl.8 A61K 009/00 DEXCEL LTD. ABRAHAM J. DOMB WO/2000/ G.E. EHRLICH (1995) LTD., AYALON TOWER, 15 TH FLOOR, 11 MENACHEM BEGIN ST., RAMAT GAN [33] US תרכיז לעשיית תרחיף לאספקת סיקלוספורין דקסל בע"מ, חדרה אברהם י. דומב ג'י.אי.ארליך (1995) בע"מ, מגדל אילון, קומה 15,רחוב מנחם בגין 11, רמת גן [57] A composition for administering a cyclosporin compound, the composition comprising: (a) a dispersible concentrate characterized by being capable of forming, upon contact with an aqueous solution, particles of a size of less than about 100 nm, said dispersible concentrate comprising: (i) at least one surfactant; and (ii) an amphiphilic solvent comprising a lower alkyl hydroxy alkanoic acid ester or a lower alkyl ester of N-alkyl pyrrolidone; and (b) a pharmaceutically effective amount of the cyclosporin compound. 2649

148 HUMAN AKT-3, PHARMACEUTICAL COMPOSITION COMPRISING IT, USES THEREOF AND METHODS FOR IDENTIFYING AGENTS WHICH INFLUENCE ITS ACTIVITY AKT 3 ממקור אנושי, תכשירי רוקחות המכילים אותו, שימושים שלו ושיטות לזיהוי חומרים המשפיעים על פעילותו [31] [32] [33] GB Int. Cl.8 A61K 038/45, 039/395, 048/00, A61P 035/00, C07K 016/40, C12N 009/12, 015/10, 015/11, 015/54, 015/70, C12Q 001/48, G01N 033/566 JANSSEN PHARMACEUTICA N.V. [87] WO/2000/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A nucleic acid molecule encoding human Akt-3 protein or a functional equivalent thereof, comprising the amino acid sequence set forth in SEQ ID No. 3, wherein a functional equivalent is an Akt-3 protein capable to phosphorylate histone H2B when expressed and purified as a recombinant GST fusion protein. SULFOALKYL ETHER CYCLODEXTRIN BASED CONTROLLED RELEASE SOLID PHARMACEUTICAL FORMULATIONS הרכבי רוקחות מוצקים לשחרור מבוקר המבוססים על סולפואלקילאתר ציקלודקסטרין [31] [87] / [32] [33] US Int. Cl.8 A61K 009/20, 009/28, 047/40, C08B 037/00, 037/16 CYDEX, INC., U.S.A. WO/2000/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV

149 [57] A controlled release solid pharmaceutical formulation comprising: a core comprising a first composition comprising a physical mixture of a therapeutic agent and at least one sulfoalkyl ether cyclodextrin, wherein a major portion of the therapeutic agent is not complexed with the sulfoalkyl ether cyclodextrin; and a coating surrounding said core and consisting of a film forming agent; wherein, said therapeutic agent of the first composition is released from the core at a controlled rate in the absence of a pore forming agent in the coating. SELECTION OF PROTEINS USING RNA-PROTEIN FUSIONS בחירת חלבונים בשימוש מיזוגי RNA חלבון [31] [87] [32] [33] US Int. Cl.8 C12N 015/00, 015/10, 015/62, C12Q 001/68, C40B 005/ G01N 033/68 THE GENERAL HOSPITAL CORPORATION, U.S.A. WO/2000/ SELIGSOHN GABRIELI & CO., זליגסון גבריאלי ושות', 31 YAVNE ST., P.O.B. 1426, רח' יבנה, 31 ת.ד. 1426, תל אביב TEL AVIV [57] A method for producing a protein library, comprising the steps of: (a) providing a population of RNA molecules, each of which comprises a translation initiation sequence and a start codon operably linked to a protein coding sequence and each of which is operably linked to a peptide acceptor at the 3' end of said protein coding sequence; (b) in vitro translating said protein coding sequences to produce a population of RNA-protein fusions; and (c) further incubating said population of RNA-protein fusions under high salt conditions, thereby producing a protein library. 2651

150 2,6,9-TRISUBSTITUTED PURINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM FOR INHIBITION OF CYCLIN DEPENDENT KINASE 2 AND IKB-A תולדות פיורין מותמרות בעמדות 6,2 ו 9 ותכשירי רוקחות המכילים אותן לעכב קינאז 2 התלוי בציקלין ו a BkI [31] [87] / [32] [33] US Int. Cl.8 A01N 043/90, A61K 031/52, A61P 009/00, 013/10, 019/00, 025/00, 029/00, 031/10, 035/00, 037/00, C07D 473/00, 473/16 CV THERAPEUTICS, INC., U.S.A. WO/2000/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] A 2, 6, 9-trisubstituted purine compound selected from the group consisting of: {2-[(2-aminoethyl) amino]-9-(methylethyl) purin-6-yl} [(4-chlorophenyl) methyl] amine; {2-[(aminopropyl) amino]-9- (methylethyl)purin-6-yl} [(4-chlorophenyl) methyl] amine; 2-[(2-aminoethyl) (6-{[(4-chlorophenyl) methyl] amino}-9-(methylethyl) purin-2- yl) amino] ethan-1-ol; 2652

151 and 2-[(2-hydroxyethyl) (6-{[(4-chlorophenyl) methyl] amino}-9-(methylethyl) purin-2- yl) amino] ethan-1-ol. METHOD AND DEVICE FOR EXECUTING METHOD STEPS התקן ושיטה לביצוע שלבים של שיטה [31] [72] [32] [33] DE Int. Cl.8 B41F 033/00, 033/16, G05B 019/04, G06F 011/34, G06K 015/02 HEIDELBERGER DRUCKMASCHINEN AG, GERMANY PETER SCHLEMM EITAN, PEARL, LATZER AND איתן, פרל, לצר וכהן צדק, COHEN ZEDEK, P.O.B , רחוב שנקר, 7 ת.ד , הרצליה HERZLIYA [57] Method of executing method steps, wherein an output signal is generated in a method step, characterized in that it is 2653 checked whether an output mode is switched on, and in that the output signal is output only if the output mode is switched on.

152 2654

153 USE OF FLUORINATED TRIAZOLES IN THE PREPARATION OF MEDICAMENTS FOR TREATING NEUROPATHIC PAIN שימוש בטריאזולים שעברו פלואורינציה להכנת תרופות לטיפול בכאב של מערכת העצבים [31] [87] / [32] [33] 09/ Int. Cl.8 A61K 031/4192, 045/06, A61P 025/00 NOVARTIS AG, SWITZERLAND WO/2000/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA US US לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] Use of a compound of the formula wherein Ph is o-fluorinated phenyl, which may be additionally substituted by 1 or 2 halogen atoms selected from the group consisting of fluorine and chlorine; R 1 is hydrogen, carbamoyl, N-(C 2 -C 5 ) alkanoylcarbamoyl or N,N-di (C 1 -C 4 ) alkylcarbamoyl; and R 2 is carbamoyl, N- (C 2 -C 5 ) alkanoylcarbamoyl or N,N-di(C 1 - C 4 ) alkylcarbamoyl, for the preparation of a pharmaceutical composition for the treatment of neuropathic pain. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2655

154 [72] PROCESS FOR PRODUCING APERTURES IN DRIPPER IRRIGATION PIPES AND DRIPPER UNITS FOR USE IN SAID PROCESS Int. Cl.8 B05B 001/20 D.R.T.S. ENTERPRISES LTD., U.S.A. RAMI HASHIMSHONY, TZADOK YEHIEL DR. YITZHAK HESS & PARTNERS, 279 HAYARKON ST., P.O.B. 6451, TEL AVIV תהליך ליצירת נקבים בצינורות השקיה בטפטוף ויחידות טפטוף לשימוש בתהליך האמור רמי השמשוני, צדוק יחיאל ד"ר יצחק הס ושותפיו, רחוב הירקון, 279 ת.ד. 6451, תל אביב [57] A dripper unit (430, 450) for use in a process for cutting holes in drip irrigation pipes, the dripper unit being characterized by having at least one outward protrusion (440) useful for forming a respective bulge in a drip irrigation pipe accommodating the dripper unit. 2656

155 NUCLEIC ACID SEQUENCES ENCODING AN ORGANIC ANION TRANSPORT PROTEIN רציפויות חומצת גרעין המקודדים חלבונים המובילים אניון אורגני [31] [87] / [32] [33] US Int. Cl.8 A61K 038/17, C07K 014/435, 016/18, 019/00, C12N 015/12, 015/63, G01N 033/53, 033/567 BRISTOL-MYERS SQUIBB COMPANY, U.S.A. WO/2000/ WOLFF, BREGMAN AND GOLLER, וולף, ברגמן וגולר, P.O.B. 1352, JERUSALEM 91013, ת.ד. 1352, ירושלים [57] A purified and isolated nucleic acid sequence encoding all or a portion of an organic anion transport protein ("OATP"), said OATP comprising an amino acid sequence selected from the group consisting of SEQ ID NO:2 (OATP2), SEQ ID NO:4 (OATP-RP2), SEQ ID NO:6 (OATP-RP3), SEQ ID NO:8 (OATP-RP4), SEQ ID NO:10 (OATP- RP5), and SEQ ID NO:12 (OATP-RP1). METHOD AND SYSTEM FOR DOWN-CONVERTING AN ELECTROMAGNETIC SIGNAL AND TRANSFORMS FOR SAME שיטה ומערכת להמרה לתדר נמוך יותר שלאות אלקטרומגנטי, ומתמרים עבורה [31] [87] / [32] / Int. Cl.8 H03D 007/00 PARKERVISION, INC., U.S.A. WO/2000/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] US US וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים [57] A method for down-converting an electromagnetic signal, comprising the steps of: (1) performing, using a switching module, a matched filtering/correlating operation, in which a duration of a sampling aperture 2657 is an approximate half cycle of a carrier signal, by convolving an approximate half cycle of the carrier signal with a representation of itself; (2) accumulating, via an integrating module, the result of the matched

156 filtering/correlating operation of step (1); and (3) repeating steps (1) and (2) for additional portions of the carrier signal, whereby the accumulation results form a down-converted signal, wherein if the carrier signal has an analog form, then the down-converted signal has the analog form and if the carrier signal has a digital form, then the down-converted signal has the digital form. STEP-BY-STEP ALKYLATION OF POLYMERIC AMINES אלקילציה בשלבים ואמינים פולימריים [31] [87] [32] [33] DE Int. Cl.8 B01D 071/68, C08G 065/48, C08L 081/06 THOMAS HARING, GERMANY WO/2000/ JMB, FACTOR & CO. LTD., ג'יי אמ בי, פקטור אנד קו בע"מ, רחוב המרפא, הר חוצבים, ת.ד.,45087 PARK, HAR HOTZVIM HI-TECH P.O.B , ירושלים JERUSALEM [57] A polymer or polymer membrane formation of the tertiary amino group to containing secondary and/or tertiary amino form an electrophilically induced groups, and containing electrophilically functional group; wherein the electrophilic induced functional groups, which is agent comprises SO 2 Cl 2 or SO 2, and at obtained by the following: deprotonating a least one other agent selected from the primary amino group on a polymeric group consisting of SO 2, SO 3, SO 2 Cl 2, amine first with an organometallic base SOCl 2, CO 2, COCl 2, PCl 5, POCl 3, Cland then reacting with an alkyl halide to PO(OR) 2, aromatic ketones, aromatic give a secondary amino group; wherein an aldehydes, aromatic carboxylic esters, and electrophilic agent is introduced after aromatic carbonyl chlorides. 2658

157 MICROORGANISM HAVING AN ATTENUATING MUTATION WHICH DISRUPTS THE EXPRESSION OF THE SSAV GENE AND AN ATTENUATING MUTATION WHICH DISRUPTS THE EXPRESSION OF THE AROC GENE מיקרואורגניזם בעל מוטציה מחלישה המשבשת את הביטוי של הגן ssav ובעל מוטציה מחלישה המשבשת את הביטוי של הגן aroc [31] [87] [32] [33] GB Int. Cl.8 A61K 039/112, C07K 014/255, C12N 001/20 MICROSCIENCE LIMITED, UNITED KINGDOM WO/2000/ DR. YITZHAK HESS & PARTNERS, ד"ר יצחק הס ושותפיו, 279 HAYARKON ST., P.O.B. 6451, רחוב הירקון, 279 ת.ד. 6451, תל אביב TEL AVIV [57] A Salmonella microorganism having an attenuating mutation which disrupts the expression of the ssav gene and an attenuating mutation which disrupts the expression of the aroc gene. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2659

158 [31] [72] [87] PROCESS FOR PREPARING (1R,2S,4R) - (-) [2(2' - {N,N - DIMETHYLAMINO} - ETHOXY)] [PHENYL1 ] - 1,7,7 - TRI - [METHYL] - BICYCLO [2.2.1] HEPTANE P [32] Int. Cl.8 C07C 213/02, 217/00, 217/02 EGIS GYOGYSZERGYAR RT., HUNGARY GYULA LUKACS, GYULA SIMIG, TIBOR MEZEI, ZOLTAN BUDAI, MARTA PORCS-MAKKAY, GYORGEY KRASZNAI, KALMAN NAGY, GYORGYI DONATH VERECZKEY, TIBOR SZABO, NORBERT NEMETH, JANOS SZYLAGYI WO/2000/ DR. MARK FRIEDMAN LTD., MOSHE AVIV TOWER, 54TH FLOOR, 7 JABOTINSKY ST., RAMAT GAN תהליך הכנה של 2 )] ( ETHOXY DIMETHYLAMINO N, N) '2)2] 2 ( ) (4R, S2, R1) HEPTANE [2.2.1] BICYCLO [METHYL] TRI 1,7,7 [[1PHENYL [33] HU ד"ר מרק פרידמן בע"מ, מגדל משה אביב, ק. 54, רח ז'בוטינסקי 7, רמת- גן [57] A process for preparing (1R, 2S, 4R)-(-)-2-[(2'-{N,N-dimethylamino}- ethoxy)]-2- [phenyl]-1,7,7-tri-[methyl]- bicyclo [2, 2,1] heptane of the formula or a pharmaceutically acceptable acid addition salt thereof, which comprises converting (+)-1,7,7-tri-[methyl-[bicycle [2, 2,1] heptane-2-one {(+)-camphor} of the formula 2660

159 into (1R, 2S, 4R)-(-)-2-[phenyl]-1,7,7-tri- [methyl]-bicyclo [2,2,1] heptane-2-ol of the formula by reacting the former with a metalloorganic compound, if necessary carrying out a decomposition of the reaction product, and reacting the (1 R, 2S, 4R)-(-)- 2-[phenyl]- 1, 7,7-tri-[methyl]-bicyclo [2,2,1] heptane-2-ol of Formula III thus obtained with a (2-{halogeno}-ethyl)- dimethylamine in the presence of a basic salt forming agent in an organic solvent and, if desired, converting the base (1R, 2S, 4R)-(-)-2-[(2-{N, N-dimethylamino}- ethoxy)]-2-[phenyl]-1,7,7-tri-[methyl]- bicyclo [2,2,1] heptane of formula I thus obtained into a salt, wherein the reaction of (1R, 2S, 4R)-(-)-2-[phenyl]- 1, 7, 7-tri- [methyl]-bicyclo[2,2,1] heptane-2-ol of formula III and (2-{halogeno}-ethyl)- dimethylamine is carried out in a medium containing one or more compounds having a 5-or 6-membered saturated heterocyclic ring with 2 oxygen ring atoms as a solvent. 2661

160 METHOD OF IDENTIFYING A POLYNUCLEOTIDE OF A MICROBE THAT IS EXPRESSED IN VIVO שיטה לזיהוי פולינוקליאוטיד של חיידק שמבוע VIVO IN [31] [87] / [32] Int. Cl.8 C12Q 001/527, 001/68 ORAGENICS, INC., U.S.A. WO/2001/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A method of identifying a polynucleotide of a microbe that is expressed in vivo comprising the steps of: (a) adsorbing antibodies against antigens that are expressed by the microbe in vivo and in vitro with cells or cellular extracts of the microbe that have been grown in vitro; (b) isolating unadsorbed antibodies; and (c) probing an expression library of the microbe's DNA or RNA with the antibodies of step (b); wherein a polynucleotide of the microbe that is expressed in vivo is isolated and identified. 2662

161 COMBINED MODALITIES FOR IMPROVED CANCER TREATMENT שילוב מנגנוני פעולה בטיפול משופר בסרטן [72] Int. Cl.8 A61K 031/517, 045/06, A61P 035/00, C07D 401/06 מדינת ישראל, משרד החקלאות, המכון STATE OF ISRAEL, MINISTRY OF AGRICULTURE, INSTITUTE OF לבעלי חיים, מינהל המחקר החקלאי, A NI MA L S CIEN CE, הדסית שרותי מחקר רפואי ופיתוח בע"מ, AGRICULTURAL RESEARCH ירושלים ORGANIZATION HADASIT MEDICAL RESEARCH קולגרד ביופרמסוטיקל בע"מ, הרצליה SERVICES & DEVELOPMENT LTD. COLLGARD BIOPHARMACEUTICALS LTD. ISRAEL VLODAVSKY, ARNON NAGLER, SHAI YARKONI, MARK PINES WEBB & ASSOCIATES, 2 PEKERIS ST., P.O.B. 2189, REHOVOT ישראל וולדבסקי, ארנון נגלר, שי ירקוני, מארק פינס ד"ר וב ושות', רח' פקריס, 2 ת.ד. 2189, רחובות [57] A pharmaceutical composition for improving the effectiveness of an antitumor treatment, containing as an active agent ingredient a quinazolinone derivative having the formula wherein: n=1-2; R 1 at each occurrence is independently selected from the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy; R 2 is a member of the group consisting of hydroxy, acetoxy and lower alkoxy; and R 3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl or pharmaceutically acceptable salts thereof, and at least one pharmaceutically acceptable carrier or diluents, further comprising a known anti-tumor agent. 2663

162 WATER SUPPLY SYSTEM מערכת אספקת מים Int. Cl.8 E03B 001/00, F16K 031/385, G05D 016/20 OPTIMUS WATER אופטימוס טכנולוגיות מים בע"מ TECHNOLOGIES LTD. REINHOLD COHN AND ריינהולד כהן ושותפיו, PARTNERS, 21 AHAD HA'AM ST.,, 21 ת.ד. 4060, תל אביב רחוב אחד העם P.O.B. 4060, TEL AVIV [57] A water supply system comprising a supply line (20) and a network of consumers (36, 40) one of which being a monitored consumer who receives the least amount of pressure, a pressure regulation system (30) comprising a pressure reducing valve (PRV) (26) associated with a pilot valve (86) present to a nominal output pressure; and a pressure control system comprising a differential control valve (DCV) (90); a pickup unit (100) for measuring a flow parameter indicative of the pressure at the monitored consumer and emitting a pressure signal to a controller (108); said controller generating a control signal (C5) responsive to the pressure signal to activate an actuator (92) of the DCV thereby governing the flow rate through the DCV, so as to obtain desired pressure at the monitored consumer, regardless of altering flow rate through the PRV. 2664

163 ISOXAZOLINE DERIVATIVE AND HERBICIDE CONTAINING THE SAME AS THE ACTIVE INGREDIENT נגזרת איסוקסאזולין וקוטל עשבים המכיל אותה כמרכיב פעיל [31] [87] / [32] Int. Cl.8 A01N 043/80, C07D 261/04 IHARA CHEMICAL INDUSTRY CO., LTD., JAPAN KUMIAI CHEMICAL INDUSTRY CO., LTD., JAPAN WO/2001/ SELIGSOHN GABRIELI & CO., 31 YAVNE ST., P.O.B. 1426, TEL AVIV [33] JP זליגסון גבריאלי ושות', רח' יבנה, 31 ת.ד. 1426, תל אביב [57] An isoxazoline derivative or a salt thereof of the formula wherein Q is a group represented by S(O) n (CR 5 R 6 ) m - (wherein n is 0 or an integer of 1 to 2, m is an integer of 1 to 3, and R 5 and R 6 are each independently a hydrogen atom, a cyano group, an alkoxycarbonyl group or a C 1 to C 6 alkyl group); and R 1, R 2, R 3, and R 4 are as defined in the specification, Y is a phenyl group substituted with 1 to 5 same or different R 7 ; each R 7 is a hydrogen atom, a C 1 to C 6 alkyl group [which may be substituted with 1 to 3 same or different halogen atoms, C 1 to C 6 alkoxy groups, hydroxyl groups, C 1 to C 6 alkylthio groups, C 1 to C 6 alkylsulfinyl groups, C 1 to C 6 alkylsufonyl groups, C 1 to C 6 alkylamino groups, di (C 1 to C 6 ) alkylamino groups, cyano groups or optionally substituted phenoxy groups], a C 1 to C 6 alkoxy group (which may be 2665 substituted with 1 to 3 same or different halogen atoms, C 1 to C 6 alkoxy groups, C 2 to C 6 alkenyl groups, C 2 to C 6 alkynyl groups, C 1 to C 6 alkoxycarbonyl groups, C 1 to C 6 alkylcarbonyl groups or C 3 to C 8 cycloalkyl groups), a C 2 to C 6 alkenyl group, a C 3 to C 8 cycloalkoxy group, a C 1 to C 6 alkylthio group (which may be substituted with 1 to 3 same or different halogen atoms or C 1 to C 6 alkoxy groups), a C 1 to C 6 alkylsulfinyl group (which may be substituted with 1 to 3 same or different halogen atoms or C 1 to C 6 alkoxy groups), a C 1 to C 6 alkylsulfonyl group (which may be substituted with 1 to 3 same or different halogen atoms or C 1 to C 6 alkoxy groups), an optionally substituted benzyloxy groups, an amino group [which may be substituted with C 1 to C 6 alkyl group, C 1 to C 6 alkylsulfonyl group, C 1 to C 6

164 alkylcarbonyl (C 1 to C 6 alkyl) group or C 1 to C 6 alkylsulfonyl (C 1 to C 6 alkyl) group], a di(c 1 to C 6 alkyl) amino group, a halogen atom, a cyano group, a nitro group, a C 1 to C 6 alkoxycarbonyl group, a C 3 to C 8 cycloalkyloxycarbonyl group, a carboxyl group, a C 2 to C 6 alkenyloxycarbonyl group, a C 2 to C 6 alkynyloxycarbonyl group, an optionally substituted benzyloxycarbonyl group, an optionally substituted phenoxycarbonyl group or a C 1 to C 6 alkylcarbonyloxy group; provided that compounds wherein R 1, R 2, R 3 and R 4 are hydrogen at the same time are excluded. [72] [87] METHOD AND APPARATUS FOR SIGNAL PROCESSING FOR ELECTROACOUSTIC TRANSDUCER Int. Cl.8 H04R 003/00 ADVANCE TECHNOLOGY AUDIO ORGANISATION (ATAO), LUXEMBOURG ANNIE CLAUDE PERRICHON, PATRICE MORCHAIN, MARC CHARBONNAUX, PIERRE PICCALUGA WO/2001/ EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA שיטה ומכשיר לעיבוד אותות עבור מתמר אלקטרו אקוסטי איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] Method in the sound reproduction frequency oscillating electric signal while field comprising the step of placing an not modifying the general aspect of the oscillator on the analog or digital electric original signal, said oscillator being selfpowered by the original signal which upon audio signal feed to at least one electroacoustic transducer, said oscillator passing through the oscillator, modifies the modifying the original electric signal to at original electric pulse into at least one least one very low amplitude and high electric micro-phase-shifted pulse. 2666

165 [31] [87] DERIVATIVES OF DICARBOXYLIC ACID HAVING PHARMACEUTICAL PROPERTIES [32] Int. Cl.8 C07C 229/00 BAYER AKTIENGESELLSCHAFT, GERMANY WO/2001/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] תולדות של חומצה דיקרבוקסילית בעלות תכונות רוקחיות DE ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] Use of compounds capable of stimulating soluble guanylate cyclase independently of the haem group in the enzyme, for preparing medicaments for the treatment of cardiovascular disorders, such as angina pectoris, ischaemia and cardiac insufficiency [31] [87] VACCINE AGAINST INTRA- CELLULAR PATHOGENS [32] Int. Cl.8 A61K 039/00, 039/385 IMMUNOBIOLOGY LIMITED, UNITED KINGDOM WO/2001/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] GB חיסון כנגד פתוגניים תוך תאיים ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A method for producing a vaccine containing an immunogenic determinant, characterised in that it comprises the steps of: (a) subjecting cells infected with an intracellular bacterial, protozoan or parasitic pathogen to stress with heat or tumour necrosis factor; and 2667 (b) extracting the endogenous stressinduced products from the stressed cells; and (c) using the extracted products as the immunogenic determinant in the preparation of the vaccine composition.

166 COMPOSITIONS COMPRISING HALOFIGINONE DERIVATIVES FOR TREATING URETHRAL STRICTURE תכשירים המכילים תולדות הלופיגינון לטיפול בהצטלקות בדרכי השתן [72] [87] Int. Cl.8 A61K 031/505, A61P 013/00, 043/00, C07D 401/06 הדסית שרותי מחקר רפואי ופתוח בע"מ, HADASIT MEDICAL RESEARCH SERVICES AND DEVELOPMENT ירושלים LTD. מדינת ישראל, מנהל המחקר החקלאי, בית STATE OF ISRAEL, דגן AGRICULTURAL RESEARCH ORGANIZATION ישראל וולדבסקי, ארנון נגלר, מארק פינס ISRAEL VLODAVSKY, ARNON NAGLER, MARK PINES WO/2001/ WEBB & ASSOCIATES, 2 PEKERIS ST., P.O.B. 2189, REHOVOT ד"ר וב ושות', רח' פקריס, 2 ת.ד. 2189, רחובות [57] A composition for local administration, for treating a urethral stricture in a subject, comprising a pharmaceutically effective amount of a compound in combination with a pharmaceutically acceptable carrier, said compound having the formula: wherein: n=1-2; R 1 at each occurrence is independently selected from the group consisting of hydrogen, halogen, nitro, benzo, lower alkyl, phenyl and lower alkoxy; R 2 is a member of the group consisting of hydroxy, acetoxy and lower alkoxy; and R 3 is a member of the group consisting of hydrogen and lower alkenoxy-carbonyl or pharmaceutically acceptable salts thereof. 2668

167 PROCESS TO SEPARATE 1,3- PROPANEDIOL OR GLYCEROL OR A MIXTURE THEREOF FROM A BIOLOGICAL MIXTURE הליך להפרדת פרופנדיול 1,3 או גליצרול, או תרכובת מהם מתרכובת ביולוגית [31] [87] / [32] [33] US 60/ US Int. Cl.8 B01D 015/00, C07C 029/00, 029/76, C12P 007/18 E.I. DUPONT DE NEMOURS AND COMPANY, U.S.A. WO/2001/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] A method for separating 1,3- (c) collecting the 1,3-propanediol and propanediol, glycerol or a mixture of 1,3- glycerol eluted from the zeolite in step (b); propanediol and glycerol selectively from (d) repeating steps (a) through (c) at least a mixture comprising the steps of: one time with the 1, 3-propanediol and (a) contacting a mixture containing a glycerol collected in step (c); and mixture of 1, 3-propanediol and glycerol (e) performing step (a)' by contacting the with a sufficient amount of a first zeolite mixture of 1, 3-propanediol and glycerol of selected from the group consisting of MFI, steps (c) or (d) with a second zeolite to MEL, BEA, MOR, FAU, LTL, GME, selectively adsorb 1, 3-propanediol or FER, MAZ, OFF, AFI, AEL, and AET, glycerol, (b)' contacting the second zeolite and materials with the same topology as of step (a)' with a desorbant of an ethanol: these zeolites, the zeolite selected on the water solution or of any C 1 -C 4 alcohol: basis of its selectivity to 1,3-propanediol water solution, (c)' collecting the 1,3- and glycerol approaching unity; propanediol or glycerol eluted from the (b) contacting the first zeolite of step (a) zeolite in step (b)', and (d)' repeating the with a desorbant of an ethanol; water series of steps (a)' through (c)' at least one solution or any C 1 -C 4 alcohol: water time to obtain a purified 1,3-propanediol or solution; glycerol. 2669

168 OPTICAL MEASUREMENTS OF PATTERNED STRUCTURES Int. Cl.8 G03B 027/54, G03F 007/20 NOVA MEASURING INSTRUMENTS LTD. NOVA MEASURING INSTRUMENTS LTD., WEIZMANN SCIENTIFIC PARK P.O.B 266 REHOVOT מדידות אופטיות על מבנים בעלי צורה נובה מכשירי מדידה בע"מ, רחובות נובה מכשירי מדידה בע"מ, וייצמן פארק למדע, ת.ד. 266, רחובות [57] An optical measurement system for measuring in a structure (W) having a pattern in the form of spaced-apart parallel elongated regions of optical properties different from that of spaces between said regions, the system comprising a broadband illuminator (8) for generating incident radiation, a spectrophotometer arrangement (30) for detecting a spectral response of the structure to the incident radiation, and an optical arrangement for directing the incident light (13) to the structure and collecting the response of the structure, said optical arrangement comprising an elongated aperture stop (32) for mounting with respect to said structure such that providing different values of numerical aperture of at least one of an incident or collected light beams in directions along and perpendicular to longitudinal axes of said elongated regions of the pattern. 2670

169 CELL CYCLE CHECKPOINT GENES AND PROTEINS ENCODED THEREBY גנים נקודת בדיקה (צ'קפוינט) של מחזור התא וחלבונים המקודדים על ידם [31] [87] / [32] [33] US Int. Cl.8 A61K 038/17, C07K 014/47, 016/18, C12N 015/12, C12Q 001/68 JANSSEN PHARMACEUTICA N.V., BELGIUM THE SCRIPPS RESEARCH INSTITUTE, U.S.A. WO/2001/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] An isolated nucleic acid encoding for a mammalian Mus81 protein. [31] [87] SURFACE MODIFIED PARTICULATE COMPOSITIONS OF BIOLOGICALLY ACTIVE SUBSTANCES / [32] Int. Cl.8 A61K 009/10 SKYEPHARMA CANADA INC., CANADA WO/2001/ PYERNIK RUTMAN, BEIT ETSION, 91 HERZL ST., P.O.B , BEER SHEVA [33] חומרים בעלי פעילות ביולוגית בצורת גרגרים מעם פני שטח ששינו US פיירניק רוטמן עו"פ, בית עציון, רח' הרצל, 91 ת.ד , באר שבע [57] A composition comprising stable, surface modified particles of a waterinsoluble biologically active substance, said particles of a mean particle size in the range of 0.01 to 10 micrometers, and dispersed in a non-aqueous carrier system comprising: 2671 (i) a non-aqueous medium in which said biologically active substance, selected from the group consisting of nifedipine, ursodiol, budesonide, paclitaxel, camptothecin, piroxicam, itraconazole, acyclovir, fenfibrate, cyclosporin, insulin

170 and derivatives thereof, is not soluble or is poorly soluble; (ii) a surfactant system consisting of at least one phospholipids surfactant which is soluble in said non-aqueous medium, wherein at least a portion of said phospholipid surfactant system adsorbs to the surface of said particles; and (iii) one or more hydrophilic substances that provide a self-dispersing property to said composition, said one or more hydrophilic substances being present in an amount of not more than 10% of the total weight of said composition; said carrier system allowing the composition to selfdisperse when added to a fluid aqueous medium to form a suspension comprising components of the non-aqueous carrier system and stable particles of the waterinsoluble, biologically active substance, said particles having a size in the range of 0.01 to 10 micrometer and having associated therewith on their surface, at least a portion of the phospholipid surfactant system. [31] [87] PREPARATION CONTAINING ACTIVE INGREDIENTS AND/OR AUXILIARY AGENTS WITH A CONTROLLED RELEASE OF THESE SUBSTANCES AND THE USE AND PRODUCTION OF THE SAME [32] Int. Cl.8 A61K 009/70 LTS LOHMANN THERAPIE- SYSTEME AG, GERMANY WO/2001/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA [33] תכשיר המכיל מרכיבים פעילים ו/או חומרי עזר בעלי שחרור מבוקר של חומרים אלה ושימוש וייצור שלהם DE לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] Preparation containing active and/or auxiliary substance(s), for the time and/or dose-controllable release of said substances, comprising a laminate made up of at least two layers in rolled or folded shape, characterized in that (a) the first layer contains at least one active or auxiliary substance, is continuous at least in sections thereof, that at least one of the parameters width and concentration of the active and/or auxiliary substance of this layer is not constant, and that (b) the second layer is continuous and possesses a lower moisture permeability than the first layer. 2672

171 PERMANENT AMNIOCYTE CELL LINE, THE PRODUCTION THEREOF AND ITS USE FOR PRODUCING GENE TRANSFER VECTORS קן תאים אמניוטים קבוע, הייצור שלו והשימוש בו לייצור וקטורים של מעבר גנים [31] [87] [32] [33] DE Int. Cl.8 C12N 005/10, 007/00, 015/00, 015/34, 015/861 CEVEC PHARMACEUTICALS GMBH, GERMANY WO/2001/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A process for producing gene Also claimed is a permanent amniocytic transfer vectors and/or adenovirus mutants, cell line comprising at least one nucleic wherein a permanent amniocytic cell line acid which brings about expression of the in used. gene products of the adenovirus E1A and E1B regions. METHOD FOR PRODUCING THERAPEUTIC AGENTS FOR ULCERS שיטה ליצור חומרים לטיפול באולקוס [31] [87] [32] [33] DE Int. Cl.8 A61K 031/4439, A61P 001/04, C07B 045/04, C07D 401/12 GRUNENTHAL GMBH, GERMANY WO/2001/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Process for the production of antiulceratives of the formula 2673

172 in which R 1, R 2 and R 3 are mutually independently selected from hydrogen, C1-C8 alkyl, C3-C8 cycloalkyl, C2-C8 fluoroalkyl and C1-C8 alkoxy, R 4 and R 5 are mutually independently selected from hydrogen, C1-C8 alkyl, C3-C8 cycloalkyl, CH 2 -C3-C8 cycloalkyl, C1-C8 alkoxycarbonyl, C1-C8 alkoxy, C1-C8 fluoroalkoxy, CF 3, C2-C8 fluoroalkyl and C(O)O-C1-C8 alkyl, and halogen, R 6 is selected from hydrogen and C1-C2 alkyl, in which process a compound of the formula is reacted with m-chloroperoxybenzoic acid in a solvent with a ph of 7.0, water is then optionally added, the solvent is optionally removed and then the crystals of the compound of the formula I are separated, characterised in that the stated solvent is an acetone/water mixture, wherein the ph of the solvent is maintained at a value of 7.0 by ph-static titration, preferably with NaOH, and/or by buffer substances dissolved in or added to the solvent, preferably mono or dibasic salts, in particular sodium or potassium carbonate and/or sodium or potassium bicarbonate and the temperature of the reaction mixture, in particular during the reaction between the compound of the formula II and m-chloroperoxybenzoic acid, is maintained between -20 o C and 30 o C, preferably between -5 o C and 5 o C. 2674

173 SUBSTITUTED OXAZOLE AND THIAZOLE DERIVATIVES, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND THEIR USE FOR THE MANUFACTURE OF MEDICAMENTS FOR THE TREATMENT OF HPPAR ALPHA DISEASE OR CONDITION תולדות אוקסאזול ותיאזול מותמרים, תכשירי רוקחות המכילים אותן והשימוש בהן לייצור תרופה לטיפול במחלות או מצבים הקשורים ל hppar אלפא [31] [87] [32] [33] GB GB Int. Cl.8 A61K 031/41, 031/44, A61P 003/00, 009/00, 029/00, 043/00, C07D 263/34, 277/56, 413/04, 417/04 GLAXO GROUP LIMITED, UNITED KINGDOM WO/2001/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A compound of the formula and pharmaceutically acceptable salts, solvates and hydrolysable esters thereof wherein; X represents O or S; R 1 and R 2 independently represent H, halogen, -CH 3 and OCH 3 ; n represents 1 or 2; X 2 represents NH, NHC 3 or O; one of Y and Z is N, and the other is O or S; R 3 represents phenyl or pyridyl (wherein the N is in position 2 or 3) and is optionally substituted by one or more halogen, NO 2, NH 2, CF 3, OCF 3, OC 1-6 straight or branched alkyl, C 1-6 straight or branched alkyl, alkenyl or alkynyl with the provision that when R 3 is pyridyl, the N is unsubsituted; R 4 represents CF 3 or CH

174 SYNTHESIS OF 2'-DEOXY -L- NUCLEOSIDES סינטזה של 2' דאוקסי L נוקלאוזידים [31] [87] / [32] [33] US Int. Cl.8 C07H 001/06, 019/00, 019/06, 019/16 PHARMASSET INC, U.S.A. WO/2001/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A process for the preparation of a 2'- deoxy-l-nucleoside comprising the steps of: (a) preparing from a suitably protected and activated L-nucleoside a 2'-S-substituted- L-nucleoside of the formula: wherein B is a heterocyclic or heteroaromatic base, R 8 and R 9 are independently hydrogen or a suitable protecting group, R 6 is an alkyl or aryl, and m is 0 or 1; and (b) reducing the 2'-S-substituted-Lnucleoside to a 2'-deoxy-L-nucleoside. 2676

175 METHODS OF BLOCKING AN ETHYLENE RESPONSE IN PLANTS USING CYCLOPROPENE DERIVATIVES שיטות עיכוב של תגובת אתלין בצמחים ע"י שימוש בנגזרות של ציקלופרופן [31] [87] / [32] [33] US 60/ US Int. Cl.8 A01N 003/02, 027/00, 031/04, 033/04, 033/12, 035/02, 035/10, 037/02, 037/06, 037/34, C07C 013/00, 013/04, 033/05, 043/188, 057/18, 069/007, 211/25, 211/62, 233/10, 251/38, 255/31 NORTH CAROLINA STATE UNIVERSITY, U.S.A. WO/2001/ DR. YITZHAK HESS & PARTNERS, ד"ר יצחק הס ושותפיו, 279 HAYARKON ST., P.O.B. 6451, רחוב הירקון, 279 ת.ד. 6451, תל אביב TEL AVIV [57] A method of inhibiting an ethylene response in a plant, comprising applying to the plant an effective ethylene responseinhibiting amount of a compound of the formula wherein: n is a number from 1 to 4; and each R is independently a saturated or unsaturated, linear or branched-chain, unsubsituted or substituted, C 6 to C 20 alkyl, alkenyl, or alkynyl. 2677

176 USE OF THYROMIMETIC COMPOUNDS IN THE PREPARATION OF MEDICAMENTS FOR THE TREATMENT OF HAIR LOSS שימוש בתרכובות טירומימתיות להכנת תרופות לטיפול בנשירת שער [31] / [32] [33] US Int. Cl.8 A61K 000/ / /395, A61P 017/14, C07C 235/70, 253/06, 311/15, 317/14, 323/18, C07D 249/10, 253/06, 257/04, 271/06, 277/20, 401/12, 403/12, 413/12, 491/02 PFIZER PRODUCTS, INC., U.S.A. LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] Use of a compound of the formula an isomer thereof, or a pharmaceutically acceptable salt of said compound or isomer; wherein the substituents are as defined in the specification, for the manufacture of a medicament for the treatment of hair loss in a mammal. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2678

177 VIDEO PLAYER WITH CODE SENSOR מערכת וידאו עם חיישן להצפנה [31] [87] PQ4392 [32] [33] AU Int. Cl.8 B41J 003/42, 029/38, G06F 003/033, 017/30, G06K 007/00, H04M 001/00, H04N 001/00 SILVERBROOK RESEARCH PTY. LTD., AUSTRALIA WO/2001/ REINHOLD COHN AND ריינהולד כהן ושותפיו, PARTNERS, 21 AHAD HA'AM ST.,, 21 ת.ד. 4060, תל אביב רחוב אחד העם P.O.B. 4060, TEL AVIV [57] A video player including: a body; at least one sensor positioned in the body so that coded data printed on a substrate is sensed by positioning the video player body relative to the substrate, the sensor generating first data from the sensed coded data; a transmitter positioned in the body for transmitting, to a computer system, said first data or second data at least partially based on the first data; a receiver positioned in the body for receiving, from the computer system, video data associated with an identity derived from the first data; and at least one display device positioned in the body for outputting a visual display based at least partially on the video data. 2679

178 DI- OR OLIGOMER OF A DIMER, TRIMER, QUATROMER OR PENTAMER OF RECOMBINANT FUSION PROTEINS חלבון מאוחה רקומביננטי בצורת די או אוליגומר, דימר, טרימר, קווטרומר או פנטאמר [31] [87] [32] [33] DE Int. Cl.8 A61K 038/17, C07K 014/525, 019/00, C12N 015/11, 015/62 APOXIS S.A., SWITZERLAND WO/2001/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A recombinant fusion protein having functional derivative thereof and at least one component A and at least one component B comprises a protein or a component B, wherein: component A protein segment selected from the group comprises a protein or a protein segment consisting of the family of C1q proteins with a biological function being a cytokine and the collectins, which oligomerizes the from the family of TNF cytokines, a recombinant fusion protein without the segment of such TNF cytokine or a effect of third molecules NAVIGATION ניווט [31] [87] [32] [33] EP Int. Cl.8 G06F 000/ / /033, H04N 005/445, 007/173 CANAL+SOCIETE ANONYME, FRANCE WO/2001/ EITAN, PEARL, LATZER AND איתן, פרל, לצר וכהן צדק, COHEN ZEDEK, P.O.B , רחוב שנקר, 7 ת.ד , הרצליה HERZLIYA [57] A method of assigning a navigation or descending a level of hierarchy between order to a plurality of objects to be these objects, the method being displayed at respective positions on a characterized in that a group of objects display, these objects being assigned to a may be traversed as a single entity at a first plurality of defined directions based on the level and individual objects or subgroups positions of the objects, said method may be traversed at a second level. comprising a step of including ascending 2680

179 USE OF INTERLEUKIN-2 FOR THE MANUFACTURE OF A PHARMACEUTICAL COMPOSITION FOR PULMONARY DELIVERY שימוש באינטרלאוקין 2 רוקחי למתן לתוך הריאה להכנת תכשיר [31] [87] / [32] / Int. Cl.8 A61K 009/08, 038/00, 047/18 NOVARTIS VACCINES AND DIAGNOSTICS, INC., U.S.A. WO/2001/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] US US ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] Use of IL-2 or biologically active variant thereof in the manufacture of a pharmaceutical composition comprising monomeric IL-2 or biologically active variant thereof for the treatment of a subject in need of Il-2 or variant thereof by 2681 administering said IL-2 or variant thereof via pulmonary inhalation, wherein said pharmaceutical composition is in a dry powder form consisting of particles having a mean diameter of less than 10 µm.

180 [31] [87] VENTILATED ITEM OF CLOTHING PD2000A [32] Int. Cl.8 A41D 027/28 GEOX S.P.A., ITALY WO/2001/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA פריט לבוש מאוורר [33] IT לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] An item of clothing (10), such as a coat, jacket or overcoat, comprising: venting elements (16) for venting warm air, produced by the user's body, that has risen in an interspace (13), said venting elements being arranged at corresponding openings of the shoulders of said item of clothing, said venting elements being constituted by at least one mesh which is applied to said corresponding openings of the shoulders of said item of clothing;. characterized in that said item of clothing comprises spacer means which are arranged at least in an internal part of the shoulders of the item of clothing so as to generate said interspace between the shoulders of the user and the fabric which the item of clothing is made of, and to lift the item of clothing and in particular to lift said at least one mesh off the user's shoulders by way of said spacer means. 2682

181 2 PHENYL (SUBSTITUTED) AMINO PYRIMIDINE DERIVATIVES, A PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS COMPRISING THE SAME AND USE THEREOF AS MEDICAMENTS נגזרות 2 פניל (מותמר) אמינו פירימידין, תהליך להכנתן, תכשירי רוקחות המכילים אותן והשימוש בהן כתרופות [31] [87] [32] [33] GB Int. Cl.8 A61K 031/505, 031/506, A61P 035/00, C07D 239/47, 417/12 ASTRAZENECA AB, SWEDEN WO/2001/ S. HOROWITZ & CO., ש. הורוביץ ושות', ZION HOUSE, בית ציון, שדרות רוטשילד 41-45, תל ROTHSCHILD BLVD., אביב TEL AVIV [57] A pyrimidine derivative of the formula having anti-cell proliferation activity, wherein: Q 1 and Q 2 are independently selected from aryl or carbon linked heteroaryl; and one of Q 1 and Q 2 or both of Q 1 and Q 2 is substituted on a ring carbon by one substituent of the formula: [provided that when Q 1 is substituted by (Ia) this substituent is not adjacent to the 2683 NH- link]; wherein:

182 X is O-; Y 1 is OH; Y 2 is H; Z is R c R d N-or a nitrogen linked heterocycle [wherein said heterocycle is optionally substituted on a ring carbon or a ring nitrogen by C 1-4 alkanoyl] wherein R c and R d are independently selected from hydrogen, C 1-4 alkyl, C 3-8 cycloalkyl; n is 1; m is 1; G is O- or S-; R 1 is selected from hydrogen, halo, hydroxy, nitro, amino, N-(C 1-3 alkyl) amino, N,N-di-(C 1-3 alkyl) amino, cyano, trifluoromethyl, trichloromethyl, C 1-3 alkyl [optionally substituted by 1 or 2 substituents independently selected from halo, cyano, amino, N-(C 1-3 alkyl) amino, N, N-di-(C 1-3 alkyl) amino, hydroxy and trifluoromethyl], C 3-5 alkenyl [optionally substituted by up to three halo substituents, or by one trifluoromethyl substituent], C 3-5 alkynyl, C 1-3 alkoxy, mercapto, C 1-3 alkylsulphanyl, carboxy and C 1-3 alkoxycarbonyl, Q is optionally substituted on a ring carbon by one to four substituents independently selected from halo, mercapto, nitro, formyl, formamido, carboxy, cyano, amino, ureido, carbamoyl, sulphamoyl, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl [wherein said C 1-4 alkyl, C 2-4 alkenyl and C 2-4 alkynyl are optionally substituted by one or more groups selected from R i ], C 1-4 alkanoyl, C 1-4 alkoxycarbonyl, heterocyclic group, C 1-4 alkyls(o), wherein a is 0 or 2 [optionally substituted by hydroxy], N-(C 1-4 alkyl) ureido, N', N'-di-(C 1-4 alkyl) ureido, N'-(C 1-4 alkyl)-n-(c 1-4 alkyl) ureido, N', N-di-(C 1-4 alkyl)-n-(c 1-4 alkyl) ureido, N-C 1-4 alkylamino, N,N-di-(C 1-4 alkyl) amino, N- (C 1-4 alkyl) sulphamoyl, N, N-di-(C 1-4 alkyl) amino, N-(C 1-4 alkyl) sulphamoyl, N, N-di-(C 1-4 alkyl) sulphamoyl, N-C 1-4 alkylcarbamoyl, N,N-di-(C 1-4 alkyl) carbamoyl and C 1-4 alkanoylamino; and also independently, or in addition to, the above substituents, Q 1 may be optionally substituted by one to two substituents independently selected from aryl, C 3-8 cycloalkyl and a heterocyclic group; wherein said aryl, C 3-8 cycloalkyl or heterocyclic group may be optionally substituted on a ring carbon by one or more groups selected from R j ; and wherein if said heterocyclic group contains an NH- moiety that nitrogen may be optionally substituted by a group selected from R k ; Q 2 is optionally substituted on a ring carbon by one to four substituents independently selected from halo, hydroxy, mercapto, nitro, formyl, formamido, carboxy, cyano, amino, ureido, carbamoyl, sulphamoyl, C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl, C 1-4 alkoxy [wherein said C 1-4 alkyl, C 2-4 alkenyl, C 2-4 alkynyl and C 1-4 alkoxy are optionally substituted by one or more groups selected from R 1 ], C 1-4 alkanoyl, C 1-4 alkoxycarbonyl, heterocyclic group, C 1-4 alkyls(o) a wherein a is 0 to 2 [optionally substituted by hydroxy], N'-(C 1-4 alkyl) ureido, N', N- di-(c 1-4 alkyl) ureido, N'-(C 1-4 alkyl)-n- (C 1-4 alkyl) ureido, N', N-di-(C 1-4 alkyl)-n- (C 1-4 alkyl) ureido, N-C 1-4 alkylamino, N,N-di-(C 1-4 alkyl) amino, N-(C 1-4 alkyl) sulphamoyl, N,N-di-(C 1-4 alkyl) sulphamoyl, N-C 1-4 alkylcarbamoyl, N-(C 1-4 alkyl) sulphamoyl, N-(C 1-4 alkyl) 2 sulphamoyl, N-(C 1-4 alkyl) carbamoyl, N- (C 1-4 alkyl) 2 carbamoyl, phenyl, phenylthio, phenoxy, C 3-8 cycloalkyl and a heterocyclic group; wherein said phenyl, phenylthio, phenoxy, C 3-8 cycloalkyl or heterocyclic group may be optionally substituted on a ring carbon by one or more groups selected from R o ; and wherein if said heterocyclic group contains an NH- moiety that nitrogen may be optionally substituted by a group selected from R p ; R j, R m and R o are independently selected from hydroxy, halo, amino, cyano, formyl, formamido, carboxy, nitro, mercapto, carbamoyl, sulphamoyl, C

183 alkyl [optionally substituted by one or more groups selected from halo, cyano, amino, N-C 1-4 alkylamino, N, N-di-(C 1-4 alkyl) amino or hydroxy], C 2-4 alkenyl [optionally substituted by one or more groups selected from halo], C 2-4 alkynyl, N-C 1-4 alkylamino, N,N-di-(C 1-4 alkyl) amino, C 1-4 alkanoyl, C 1-4 alkanoyloxy, C 1-4 alkoxy [optionally substituted by one or more groups selected from halo], C 1-4 alkoxycarbonyl, N-C 1-4 alkylcarbamoyl, N,N-di-(C 1-4 alkyl) carbamoyl, C 1-4 alkanoylamino, C 1-4 alkyls(o) a wherein a is 0 to 2, C 1-4 alkylsulphonylamino, N-(C 1-4 alkyl) sulphamoyl, N-(C 1-4 alkyl) 2 sulphamoyl, phenyl, C 3-8 cycloalkyl and a heterocyclic group; and R k, R n and R p are independently selected from C 1-4 alkyl, C 1-4 alkanoyl, C 1-4 alkylsulphonyl, C 1-4 alkoxycarbonyl, carbamoyl, N-(C 1-4 alkyl) carbamoyl, N,N-(C 1-4 alkyl) carbamoyl, benzyl, benzyloxycarbonyl, benzoyl and phenylsulphonyl; or a pharmaceutically acceptable salt or in vivo hydrolysable ester thereof PHOTOVOLTAIC DEVICE FORMING A GLAZING התקן פוטו-וולטי היוצר זיגוג [31] [87] /16693 [32] Int. Cl.8 H01L 027/142 ENERGY SYSTEMS INTERNATIONAL BV, THE NETHERLANDS WO/2002/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] FR סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] Photovoltaic device (1) comprising a plurality of photovoltaic cells (2) of the p- i-n type placed on a substrate (3), wherein said cells are positioned parallel to one another and wherein electrically conductive layers (7) connect the p-type layer (5) of every cell with the n-type layer of the adjacent cell on one side and connect the n-type layer (6) of said same cell with the p-type layer of the adjacent cell on the other side, except for cells located at the outer border of the device, so as to electrically connect all the consecutive cells of the device in series, characterised in that at least the p-type layer and the n-type layer of a photovoltaic cell of the photovoltaic device are both located in the same layer on the substrate, parallel to one another and on top of the electrically conductive layer. 2685

184 METHOD AND APPARATUS FOR MEASURING CHANNEL STATE INFORMATION שיטה והתקן למדידת מידע מצב ערוץ [31] [87] / [32] [33] US Int. Cl.8 H04B 001/69, 007/00, H04J 011/00, 015/00, H04Q 007/38 QUALCOMM INCORPORATED, U.S.A. WO/2001/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] A method for measuring and reporting channel state information (CSI) in a multiple input/multiple output (MIMO) system, comprising the steps of: assigning a plurality of disjoint subchannel sets to a plurality of transmit antennas; transmitting a plurality of Orthogonal Frequency Division Multiplexed (OFDM) pilot signals from a transmitter unit to a plurality of receiver units, wherein each of the plurality of OFDM pilot signals is transmitted on at least one of the plurality of disjoint subchannel sets; demodulating the plurality of disjoint sub-channel sets, wherein the step of determining the CSI uses the demodulated plurality of OFDM pilot signals; transmitting the CSI of the plurality of disjoint sub-channel sets to the transmitter unit; and preconditioning a transmission symbol. 2686

185 The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. AMINO ACID SEQUENCES FACILITATING PENETRATION OF A SUBSTANCE OF INTEREST INTO CELLS AND/OR CELL NUCLEI רצפי חומצות אמינו העוזרים לחדירת חומר בעל התענינות לתוך תאים ו/או לתוך גרעיני תאים [31] [87] /02621 [32] [33] FR Int. Cl.8 A61K 048/00, C07K 005/11, 007/06, 007/08, 014/47, 017/14, C12N 001/19, 005/10, 015/87 DIATOS, FRANCE WO/2001/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] Intracytoplasmic and/or intranuclear transfer vector for a substance of interest, 2687 characterised in that it comprises at least one amino acid sequence reacting in vivo

186 with aminoglycans and that is derived from human lipoprotein B coupled to at least one antibody fragment. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. DEVICE FOR TRANSFER OF DATA FROM EXTERNAL CARRIER TO HANDHELD ELECTRONIC DEVICE התקן להעברת נתונים ממנשא חיצוני למכשיר יד אלקטרוני [72] Int. Cl.8 G06F 003/00, 003/023, G06Q 002/00000 SPIRAL SOLUTIONS LTD ספירל סולושנס בע"מ, משגב דגלס יורק מלובסקי, עמיחי בן-דוד, אהוד MALAWSKY, DOUGLAS YORK AMIHAY BEN-DAVID, EHUD לוי LEVY NAOMI ASSIA & CO. LAW OFFICES, 32 HABARZEL ST. RAMAT HACHAYAL TEL AVIV נעמי אסיא ושות' משרד עורכי דין, רח' הברזל 32 רמת החייל, תל-אביב [57] A device for transferring data to a telephone, personal digital assistant or cellular telephone, said device comprising: (a) a reader comprising: a slot adapted to receive a card; a processor and dedicated hardware adapted to read data from a memory component of a card, and to transmit said data via a phone bridge to a telephone, personal digital assistant or a cellular telephone; (b) a card having at least one data substructure retained within a memory component of said card; said card comprising appropriate circuitry and hardware for allowing retrieval and transmission of said data to said reader; (c) a phone bridge connectable to said reader, wherein said phone bridge is adapted to transmit data from said reader to a telephone, personal digital assistant or a cellular telephone; wherein upon insertion of said card into said reader slot, a data substructure can be selected from said card and transmitted to a remote location via said reader and said phone bridge, by means of a telephone, personal digital assistant or cellular telephone. 2688

187 ALLOCATION OF RADIO RESOURCES IN A CDMA2000 CELLULAR SYSTEM הקצאת משאבי רדיו במערכת סלולרית CDMA Int. Cl.8 H04B 007/005, H04Q 007/20, 007/38 FAZAN COMMUNICATIONS LLC, U.S.A. קבוצת איתן מהולל, עורכי דין ועורכי GROUP, EITAN MEHULAL LAW 10 ABBA EBEN BLVD., פטנטים, P.O. B. 2081, שדרות אבא אבן, 10 ת.ד. 2081, הרצליה HERZLIYA [57] In a data transmission system for transmitting data from a transmitter to a plurality of subscriber units, wherein: fundamental channels (FCHs) are combined, in a hierarchical manner, into transmission channels of higher levels, 2689 each configured to carry data at a corresponding rate level, which is a correspondingly higher rate than the fundamental rate; and any unused channel, at any level, is periodically allocated to a corresponding one of the subscriber units,

188 in order to carry data to the subscriber unit from a buffer storage during a subsequent period; a method for periodically allocating channels to subscriber units, comprising, prior to the beginning of any period; (a) identifying all active subscriber units being in communication with the transmitter and for which there are data, exceeding a given minimal quantity, stored in the buffer storage; (b) calculating for each active subscriber unit one or more priority factors as a function of associated power levels; (c) on the basis of said priority factors, allocating at least one channel, to a corresponding active subscriber unit; (d) repeating the channel allocation with respect to any active subscriber units to which no channels have yet been allocated, subject to an availability of unallocated channels and subject to a limitation of maximum transmitter power. 2690

189 DRIVING HEADS FOR FASTENERS ראשים מסתובבים למכשירי הידוק [31] [87] [32] [33] GB Int. Cl.8 B25B 015/00, F16B 023/00, 041/00 UNI-SCREW WORLDWIDE, INC., U.S.A. WO/2001/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Fastener having a driving head which includes at least two superimposed non-circular recesses (11, 12, 13) for receiving the bit of a driver with which driver a torque can be applied to operate the fastener, at least one of said recesses having a different diameter to the other(s), wherein the diameter of a recess is its longest dimension parallel to the top surface of the fastener, characterised in that the fastener comprises a security feature whereby said torque needs to be applied to at least two of said recesses in order to operate the fastener. 2691

190 [72] FIBRE OPTIC COUPLER Int. Cl.8 G02B 006/38 BIOSCAN LTD. ILAN GREENBERG, AVRAM MATCOVICH PEARL COHEN ZEDEK LATZER, 5 SHENKAR ST., P.O.B , HERZLIYA מחבר לכבל אופטי ביוסקאן בע"מ, יקנעם עילית אילן גרינברג, אברם מטקוביץ פרל כהן צדק לצר, מרכז גב- םי 1, רח' שנקר, 5 ת.ד , הרצליה [57] A fiber optic coupler assembly (16) for optically aligning a sectioned fibre optic cable, the cable having a first end (10) and a second end (12) and comprising one or more fibre optic cores, the assembly comprising a first holder for holding the first end; a second holder for holding the second end coupled to the first end; a retractor for retracting the second end; an aligning unit (40) comprising a resilient construction having a conduit passing through it, for linear alignment of the ends, and a rotor for rotating one end with respect to the other end; whereby the first and second ends are coupled by the respective holders and whereby the second end can be linearly aligned in the conduit of the aligning unit, retracted using the retractor, and rotated to obtain rotational alignment of the fiber cores of the ends. 2692

191 SUBSURFACE SOIL INJECTION APPARATUS AND METHOD התקן ושיטה להזרקה תת קרקעית של אדמה [31] [87] / [32] Int. Cl.8 A01C 023/00 ARYSTA LIFESCIENCE NORTH AMERICA CORPORATION, U.S.A. WO/2002/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] US וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים [57] An apparatus for introducing a discrete, predetermined amount of a material into soil at a plurality of predetermined points in the soil, characterised in that it includes: a container (50) for holding the material to be introduced into the soil; tubing (60) in fluid connection with the container at a first end thereof, the tubing having one distal end for introducing the material into the soil; at least one shank (20) for placing the distal end of the tubing at a predetermined depth in the soil during the introduction of the material into the soil, wherein the distal end of the tubing is attached to the at least one shank such that the distal end of the tubing on the shank is placed at the predetermined depth in the soil when the material is introduced into the soil, and a switch (90) for controlling the flow of the material through the tubing, the switch being operable between an open state for introducing the discrete, predetermined amount of the material into the soil at the predetermined points in the soil, and a closed state in which the shank is situated between the predetermined points in the soil. 2693

192 [31] [87] APPARATUS AND METHOD FOR MEASURING ALIGNMENT OF METERED DOSE INHALER VALVES [32] Int. Cl.8 A61M 015/00, G01B 011/14 GLAXO GROUP LIMITED, UNITED KINGDOM WO/2001/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] התקן ושיטה למדידת המערך של שסתומי משאף בעל מינונים מדודים US ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A measuring apparatus comprising: (a) a housing (10) defining an inner chamber therein; (b) a transducer (80) mounted to the housing and including a probe extending into the inner chamber; and (c) a mounting platform disposed within the inner chamber of the housing and adapted for mounting an object thereon having opposing first and second end surfaces, the measuring apparatus being adapted for relative rotational movement between the mounting platform and the transducer probe so that the probe is caused to contact a portion of the first end surface of the object. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2694

193 NORBUFALIN DERIVATIVES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM נגזרות של 19 נורבופאלין, הכנתן ותכשירי רוקחות המכילים אותן [31] [87] [32] [33] IL Int. Cl.8 A61K 031/56, A61P 043/00, C07J 017/00 YISSUM RESEARCH יישום חברה לפיתוח המחקר של DEVELOPMENT COMPANY OF האוניברסיטה העברית בירושלים, THE HEBREW UNIVERSITY OF ירושלים JERUSALEM WO/2001/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] Compounds of the formula wherein R 1 is hydrogen or a hydroxy protecting group; R 2 is OH or hydrogen; R 3 is selected from one of the following groups: 2695

194 R 4 is hydrogen or OH; R 5 is hydrogen or OH; and the dashed line denotes an optional double bond; and isomers and pharmaceutically acceptable salts thereof. GIMBALED SCANNING SYSTEM AND METHOD מערכת ושיטה לסריקה על ז'ימבאלים [31] [87] / [32] Int. Cl.8 G02B 026/10 RAYTHEON COMPANY, U.S.A. WO/2002/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A system (10) for scanning at least a portion of a field-of-regard, comprising: means for sensing (30) an image, and means for directing the image from the field-of-regard to the means for sensing, the means for directing including a reflecting surface (20) that is rotatable about a central axis (38), an adjustment axis (24) in a plane parallel to the central axis, and elevation axis transverse to the adjustment axis (24) and a flip axis (40) perpendicular to the central axis. 2696

195 PIPERIDINYL BENZAMIDINES AND PHARMACEUTICAL COMPOSITIONS COMPRISING THEM פיפרידינים בנזאמינים ותכשירי רוקחות המכילים אותם [31] [87] / [32] [33] US GB 09/ US Int. Cl.8 A61K 031/395, A61P 043/00, C07D 211/16, 211/70, 295/16, 401/04, 401/06, 401/10, 401/14, 405/10, 409/06, 409/10, 409/14, 417/10, 417/14, 471/04 AVENTIS PHARMACEUTICALS INC., U.S.A. WO/2001/ EITAN, PEARL, LATZER AND איתן, פרל, לצר וכהן צדק, COHEN ZEDEK, P.O.B , רחוב שנקר, 7 ת.ד , הרצליה HERZLIYA [57] A compound of the formula wherein Z is a carbon or nitrogen atom; Ar is an aryl group, a monocyclic is a 4 to 7-membered azaheterocyclyl or a 4 to 7-membered azaheterocyclenyl group; heteroaryl group, or a bicyclic azaheteroaryl group which includes a first proximal ring that is attached to the is a single or double bond, provided that when Z is a nitrogen atom, then is a single bond; 2697

196 moiety and a ring distal to said first ring said distal ring including at least one nitrogen atom; X a, X b, X c are independently selected from hydrogen, R 4 R 5 N-, (hydroxy)nh-, (alkoxy)nh-, R 6 O-, R 4 R 5 NCO-, R 4 R 5 NSO 2 -, -R 6 CO-, halo, R 4 R 5 NCO-, R 4 R 5 NSO 2 -, -R 6 CO-, halo, cyano, nitro R 7 (O)C(CH 2 ) q -and ;and when is a bicyclic heteroaryl group, then X c is a substituent that is at the and X c is selected from the group consisting of H, hydroxyl and H 2 N-, (optionally substituted lower alkyl) NH (hydroxyl) NH-, and (alkoxy) NH-; R 4 and R 5 are independently H or optionally substituted lower alkyl, or one of R 4 and R 5 is H and the other of R 4 and R 5 is R 7 (O)CCH 2 - or lower acyl; R 6 is H, optionally substituted lower alkyl, lower acyl or R 7 (O)CCH 2 -; R 7 is H, optionally substituted lower alkyl, alkoxy or hydroxyl; R 8 and R 9 taken together are =NR 10 ; R 10 is hydrogen, R 11 O 2 C-, R 11 O- HO-, cyano, R 11 CO-, NCO-, lower alkyl, nitro, or Y 1a Y 2a N-; R 11 is alkyl, aralkyl, or heteroaralkyl; R 12 is hydrogen, lower alkyl, aryl (lower alkyl), heteroaryl (lower alkyl), lower acyl, aroyl, or heteraroyl; R 13 is hydrogen, lower alkyl; a pharmaceutically acceptable salt thereof, an N-oxide thereof, a hydrate thereof or a solvate thereof. 2698

197 METHOD FOR PRODUCING 2- CHLORO-5-CHLOROMETHYL-1, 3-THIAZOLE שיטה לייצור 1,3 תיאזול 2 כלורו 5 כלורומתיל [31] [87] A895/2000 [32] Int. Cl.8 C07D 277/32 SYNGENTA PARTICIPATIONS AG, SWITZERLAND WO/2001/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA [33] AT לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] A process for the preparation of 2- chloro-5-chloromethyl-1,3-thiazole, which is characterized in that (a) alkyl isothiocyanate of the formula CH 2 =CH---CH 2 ---NCS is reacted at a temperature of from -40 o C. to 30 o C., in a solvent that is inert under the reaction conditions, optionally in an inert gas atmosphere, with from 1 to 2 mol of a chlorinating agent per mol of allyl isothiocyanate, said chlorinating agent being selected from the group consisting of Cl 2, SO 2, Cl 2, PCl 3, PCl 5 and POCl 3 ; (b) to the reaction mixture resulting from step (a), at a temperature of from 0 o C. to the boiling temperature of the reaction mixture, from 1 to 5 mol of an oxidizing agent per mol of allyl isothiocyanate are added, said oxidizing agent being selected from the group consisting of Br 2, an N- haloimide and a dihalodialkylhydantoin, optionally with the application of UV light and/or in the presence of a suitable initiator, optionally in an inert gas atmosphere; and (c) the 2-chloro-5-chloromethyl-l,3- thiazole is isolated from the reaction mixture resulting from step (b); and, if desired, (d) the isolated 2-chloro-5-chloromethyl- 1,3-thiazole resulting from step (c) is converted by crystallization into highpurity 2-chloro-5-chloromethyl-1,3- thiazole. 2699

198 CRYSTALLINE AND AMORPHOUS FORMS OF A TRIAZOLO (4,5-D) PYRIMIDINE COMPOUND צורה גבישית ואומורפית של תרכובת של טריאזולו (5,4 D) פירימידין [31] [72] [87] [32] [33] GB Int. Cl.8 A61K 031/519, A61P 009/10, C07D 487/04 ASTRAZENECA AB, SWEDEN MARTIN BOHLIN, STEVE COSGROVE, BO LASSEN WO/2001/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A compound of the formula: in a substantially crystalline form selected from: a compound of formula (I) characterised by an X-ray powder diffraction pattern containing specific peaks of high intensity at 5.3 o (±0.1 o ), 20.1 o (±0.1 o ), 20.7 o (±0.1 o ), 21.0 o (±0.1 o ) and 21.3 o (±0.1 o )2Ө; a compound of formula (I) characterised by an X-ray powder diffraction pattern containing specific peaks of high intensity at 14.0 o (±0.1 o ), 17.4 o (±0.1 o ), 18.4 o (±0.1 o ), 21.4 o (±0.1 o ) and 24.1 o (±0.1 o ) 2Ө; and a compound of formula (I) characterised by an X-ray powder diffraction pattern containing specific peaks of high intensity at 4.9 o (±0.1 o ), 9.2 o (±0.1 o ), 11.6 o (±0.1 o ), 15.6 o (±0.1 o ) and 16.4 o (±0.1 o ) 2Ө. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2700

199 2-AMINOCARBONYL-9H-PURINE DERIVATIVES נגזרות של 2 אמינוקרבוניל H9 פורין [31] [87] [32] [33] GB GB GB Int. Cl.8 A61K 031/7076, A61P 001/04, 003/10, 009/00, 009/10, 009/12, 011/00, 011/02, 011/06, 015/08, 015/16, 017/00, 017/02, 017/04, 017/06, 019/02, 025/08, 025/18, 025/28, 029/00, 031/04, 037/08, 043/00, C07H 019/00, 019/16 PFIZER INC., U.S.A. WO/2001/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A compound of the formula: or a pharmaceutically acceptable salt or solvate thereof, wherein R 1 is H, C 1 -C 6 alkyl or fluorenyl, said C 1 - C 6 alkyl being optionally substituted by 1 or 2 substituents each independently selected from phenyl and naphthyl, said phenyl and naphthyl being optionally substituted by C 1 -C 6 alkyl, C 1 -C 6 alkoxy, halo or cyano; (A) R 2 is H or C 1 -C 6 alkyl, R 15 is H or C 1 - C 6 alkyl, and X is either (i) unbranched C 2 - C 3 alkylene optionally substituted by C 1 -C 6 alkyl or C 3 -C 8 cycloalkyl, or (ii) a group of the formula: -(CH 2 ) n -W-(CH 2 ) p - where W is C 5 -C 7 cycloalkylene optionally 2701 substituted by C 1 -C 6 alkyl, n is 0 or 1 and p is 0 or 1, or (B) R 15 is H or C 1 -C 6 alkyl, and R 2 and X, taken together with the nitrogen atom to which they are attached, represent azetidin-3-yl, pyrrolidin-3-yl, piperidin-3- yl, piperidin-4-yl, homopiperidin-3-yl or homopiperidin-4-yl, each being optionally substituted by C 1 -C 6 alkyl, or (C) R 2 is H or C 1 -C 6 alkyl, and R 15 and X, taken together with the nitrogen atom to which they are attached, represent azetidin-3-yl, pyrrolidin-3-yl, piperidin-3- yl, piperidin-4-yl, homopiperidin-3-yl or homopiperidin-4-yl, each being optionally substituted by C 1 -C 6 alkyl;

200 either, R 3 and R 4, taken together with the nitrogen atom to which they are attached, represent azetidinyl, pyrrolidinyl, piperidinyl, piperazinyl, homopiperidinyl or homopiperazinyl, each being optionally substituted on a ring nitrogen or carbon atom by C 1 -C 6 alkyl or C 3 -C 8 cycloalkyl and optionally substituted on a ring carbon atom not adjacent to a ring nitrogen atom by NR 6 R 7, or, R 3 is H, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl or benzyl and R 4 is (a) azetidin-3-yl, pyrrolidin-3-yl, piperidin- 3-yl, piperidin-4-yl, homopiperidin-3-yl or homopiperidin-4-yl, each being optionally substituted by C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, phenyl, benzyl or het, or (b) (C 2 -C 6 alkylene)-r 8, (c) (C 1 -C 6 alkylene)-r 13, or (d) C 1 -C 6 alkyl or C 3 -C 8 cycloalkyl; R 5 is CH 2 OH or CONR 14 R 14 ; R 6 and R 7 are either each independently H or C 1 -C 6 alkyl or, taken together with the nitrogen atom to which they are attached, represent azetidinyl, pyrrolidinyl or piperidinyl, said azetidinyl, pyrrolidinyl and piperidinyl being optionally substituted by C 1 -C 6 alkyl; R 8 is (i) azetidin-1-yl, pyrrolidin-1-yl, piperidin-1-yl, morpholin-4-yl, piperazin- 1-yl, homopiperidin-1-yl, homopiperazin- 1-yl or tetrahydroisoquinolin-1-yl, each being optionally substituted on a ring carbon atom by C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, phenyl, C 1 -C 6 alkoxy-(c 1 -C 6 )- alkyl, R 9 R 9 N-(C 1 -C 6 )-alkyl, fluoro-(c 1 - C 6 )-alkyl, -CONR 9 R 9,-COOR 9 or C 2 -C 5 alkanoyl, and optionally substituted on a ring carbon atom not adjacent to a ring nitrogen atom by fluoro-(c 1 -C 6 )-alkoxy, halo, -OR 9, cyano,- S(O) m R 10, -NR 9 R 9, - SO 2 NR 9 R 9, -NR 9 COR 10 or NR 9 SO 2 R 10, and said piperazin-1-yl and homopiperazin-1-yl being optionally substituted on the ring nitrogen atom not attached to the C 2 -C 6 alkylene group by C 1 -C 6 alkyl, phenyl, C 1 -C 6 alkoxy (C 2 - C 6 )-alkyl, R 9 R 9 N-(C 2 -C 6 )-alkyl, fluoro-( C 1 -C 6 )-alkyl, C 2 -C 5 alkanoyl, -COOR 10, C 3 -C 8 cycloalkyl, -SO 2 R 10, -SO 2 NR 9 R 9 or CONR 9 R 9, or (ii) NR 11 R 12 ; R 9 is H, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl or phenyl; R 10 is C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl or phenyl; R 11 is H, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl or benzyl; R 12 is H, C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, phenyl, benzyl, fluoro-( C 1 -C 6 )-alkyl,- CONR 9 R 9, -COOR 10, C 2 -C 5 alkanoyl or SO 2 NR 9 R 9 ; R 13 is (a) phenyl, pyridin-2-yl, pyridin-3-yl or pyridin-4-yl, each being optionally substituted by C 1 -C 6 alkyl, C 1 -C 6 alkoxy, - (C 1 -C 3 alkylene)- (C 1 -C 6 alkoxy), halo, cyano, -(C 1 -C 3 alkylene)-cn, -CO 2 H, -(C 1 - C 3 alkylene)-co 2 H, -CO 2 (C 1 -C 6 alkyl), - (C 1 -C 3 alkylene)-co 2 (C 1 -C 6 alkyl), -(C 1 -C 3 alkylene)-nr 14 R 14, -CONR 14 R 14 OR (C 1 - C 3 alkylene)-conr 14 R 14, or (b) azetidin- 2-yl, azetidin-3-yl, pyrrolidin-2-yl, pyrrolidin-3-yl, piperidin-2-yl, piperidin-3- yl, piperidin-4-yl, homopiperidin-2-yl, homopiperidin-3-yl or homopiperidin-4-yl, each being optionally substituted by C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, phenyl, benzyl or het; R 14 is H or C 1 -C 6 alkyl optionally substituted by cyclopropyl; m is 0, 1 or 2; Y is CO, CS, SO 2 or C=N(CN); and "het", used in the definition or R 4 and R 13, is a C-linked, 4- to 6-membered ring, heterocycle having either from 1 to 4 ring nitrogen heteroatoms or 1 or 2 nitrogen ring heteroatoms and 1 oxygen or 1 sulphur ring heteroatom, optionally substituted by C 1 -C 6 alkyl, C 3 -C 8 cycloalkyl, C 1 -C 6 alkoxy, C 3 -C 8 cycloalkoxy, hydroxy, oxo or halo. 2702

201 LENS PRODUCTION METHOD AND PROCESS Int. Cl.8 G02B 003/00 SHAMIR SPECIAL OPTICAL PRODUCTS LTD PEARL COHEN ZEDEK LATZER, 5 SHENKAR ST., P.O.B , HERZLIYA התקן ושיטה לייצור עדשה שמיר מוצרים אופטיים מיוחדים בע"מ פרל כהן צדק לצר, מרכז גב- םי 1, רח' שנקר, 5 ת.ד , הרצליה [57] A method for processing a lens blank provided with a first surface and a second surface to be processed by a processing equipment for imparting the first and the second surface with required surface topography and obtaining a corresponding first optical face and a second optical face of a lens, said method comprising positioning the lens blank in a gripping device and gripping the lens blank by a gripping device while relying on reference datum indications enabling orientation of the lens blank to obtain the required surface topography of both optical faces of the lens, and wherein not more than one reference datum indication extends on the first optical face of the lens. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו TRANSGENIC ANIMAL IN WHICH GSK-38 PROTEIN IS OVER-EXPRESSED חיה טרנזגנטית אשר בה חלבון 38 GSK במצב בטוי יתר [31] [87] [32] Int. Cl.8 A01K 067/00, C12N 009/12 CONSEJO SUPERIOR INVESTIGACIONES CIENTIFICAS, SPAIN UNIVERSIDAD AUTONOMA DE MADRID (UAM), SPAIN WO/2001/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] GB וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים

202 [57] A transgenic non-human animal in the animal under the control of a wherein GSK-3β protein is over-expressed CamKIIa promoter. [31] [87] DRIP IRRIGATION HOSE AND METHOD OF MAKING SAME / [32] Int. Cl.8 B05B 001/20 AMIR COHEN WO/2002/ G.E. EHRLICH (1995) LTD., AYALON TOWER, 15 TH FLOOR, 11 MENACHEM BEGIN ST., RAMAT GAN צינור השקיה בטפטוף ושיטה ליצורו [33] US אמיר כהן ג'י.אי.ארליך (1995) בע"מ, מגדל אילון, קומה 15,רחוב מנחם בגין 11, רמת גן [57] A drip irrigation hose, comprising: a hose (2) conducting pressurized water through its interior and formed with a plurality of outlets for discharging the water at longitudinally-spaced locations along the length of the hose; and a plurality of emitter elements (4) secured to said hose at longitudinally-spaced locations along its length to define a plurality of turbulent flow passageways each in communication with the interior of the hose for discharging water from each hose outlet at a slow rate; characterized in that each of said turbulent flow passageways defined by said emitter elements includes a relatively elastic material coextruded with a relatively stiff material different from said elastic material, such that the relatively elastic material is pressure-deformable as compared to the relatively stiff material to change the turbulent flow through each emitter element in response to the pressure of the water in the hose at the respective emitter element. 2704

203 [31] [87] ENANTIOMER SEPARATION OF PIPERIDONE DERIVATIVES WITH SIMULTANEOUS IN SITU RACEMIZATION OF THE UNWANTED ENANTIOMER [32] Int. Cl.8 C07D 211/74 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG, GERMANY WO/2001/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] הפרדה אננטיומרית של תולדות פיפרידיון תוך רצמיזציה בו זמנית של האננטיומר הלא רצוי DE ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A process for dynamically separating the enantiomers of a piperidone derivative of the formula wherein: (b) adding a second solution containing the R 1 is aryl optionally mono-to piperidone derivative to the first solution polysubstituted, heteroaryl, which is linked to precipitate out the desired enantiomer of to the chiral center via at least one carbon the piperidone derivative as a salt of the atom belonging to the methylene bridge, or optically active acid while racemizing the straight-chain or branched C 1 -C 8 alkyl unwanted enantiomer of the piperidone optionally mono- to polysubstituted by derivative in solution and further halogen; R 2 and R 3, which are identical or precipitating the desired enantiomer of the different, are each straight-chain or piperidone derivative formed from the branched C 1 -C 6 -alkyl; and n is 0, 1, 2 or 3, racemization of the unwanted enantiomer the process comprising: of the piperidone derivative in solution; (a) dissolving an optically active acid and and optionally catalytic amounts of a sulfonic (c) separating the desired enantiomer of acid in a solvent to make a first solution the piperidone derivative as a salt of the maintained at a desired temperature; optically active acid. 2705

204 [31] PRODUCTION METHOD OF A 2,6- DICHLOROPHENOL COMPOUND [32] Int. Cl.8 C07C 041/22, 043/00, 043/23 SUMITOMO CHEMICAL COMPANY, LIMITED, JAPAN DR. YITZHAK HESS & PARTNERS, 279 HAYARKON ST., P.O.B. 6451, TEL AVIV [33] JP שיטת ייצור של תרכובת 2 6, דיכלורופנול ד"ר יצחק הס ושותפיו, רחוב הירקון, 279 ת.ד. 6451, תל אביב [57] A production method of a 2, 6- dichlorophenol compound of the formula wherein R represents a 3,3-dihalo-2- propenyl group, which comprises making a phenol compound of the formula wherein R has the same meaning mentioned above, react with sulfuryl chloride in the presence of a secondary amine. 2706

205 COMPUTER STORAGE APPARATUS AND METHOD FOR DATA MIRRORING התקן לאיחסון במחשב והליך לייצור תמונות ראי של נתונים [31] [72] [87] / [32] [33] US 60/ US 60/ US Int. Cl.8 G06F 003/06, 011/00, 011/20, 012/00 MIRALINK CORPORATION, U.S.A. RON MCCABE, TRACY CAMP, STUART CARD, DAVID J. SCHROEDER WO/2001/ JMB, FACTOR & CO. LTD., ג'יי אמ בי, פקטור אנד קו בע"מ, רחוב המרפא, הר חוצבים, ת.ד.,45087 PARK, HAR HOTZVIM HI-TECH P.O.B , ירושלים JERUSALEM [57] A computer storage apparatus, comprising: means for receiving change data from a source, the change data received in a mirroring unit; and means for storing a changed logical block number indicating a logical block on the source corresponding to the change data, the means for storing the changed logical block number including a data structure including block checksums corresponding to the change data; and means for transmitting the block checksums across a journey link to a mirroring unit rather than transmitting change data across the journey link during a resynchronization of the mirroring unit and the computer storage apparatus. 2707

206 METHOD FOR DETECTING ACTIVE INGREDIENTS OF MEDICAL VALUE שיטה לזיהוי מרכיבים פעילים בעלי ערך רפואי [31] [87] [32] Int. Cl.8 C12Q 001/37 SANOFI-AVENTIS DEUTSCHLAND GMBH, GERMANY WO/2001/ EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] DE איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] A method to determine whether a test substance inhibits or acts as a ligand of at least one binding domain of a protein, comprising: incubating said test substance with a mixture, wherein said mixture comprises: (a) the protein, (b) at least one marker substrate, and (c) at least one substrate; and determining whether the test substance inhibits or acts as a ligand of at least one binding domain of the protein by comparing the conversion of the marker substrate in the presence of the test substance with the corresponding conversion in control mixtures A and B, 2708

207 wherein the protein contains at least one catalytic domain and at least one binding domain, wherein the marker substrate is converted by said at least one catalytic domain of the protein, wherein the substrate is capable of binding to said at least one catalytic domain and to said at least one binding domain of the protein, wherein the control mixture A comprises the protein and the marker substrate; and the control mixture B comprises the protein, the substrate, and the marker substrate, and wherein the test substance is an inhibitor or ligand of said at least one binding domain of the protein if the conversion of the marker substrate in the presence of the test substance is between the values obtained with control mixtures A and B POTENT IMMUNOSTIMULANTS FROM MICROALGAE ממריצים של המערכת החיסונית המופקים ממיקרו אצות [31] [87] / [32] [33] US Int. Cl.8 A61K 003/ /715, 031/726, 031/736, 035/00, C07H 001/08 THE UNIVERSITY OF MISSISSIPPI, U.S.A. WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Immunostimulatory preparations isolated from microalgae comprising polysaccharides extractable by a solvent comprising water or a mixture of water and at least one lower alkyl alcohol where the alkyl portion is from 1 to 4 carbon atoms and where the active polysaccharides have apparent molecular weights above approximately 2 million Daltons. 2709

208 POLYMERIC MICELLE COMPOSITIONS תכשירים בצורת מיצלות מפולימרים [31] [87] [32] Int. Cl.8 A61K 009/00, 009/107, 009/51 LABOPHARM, INC., CANADA. WO/2002/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] US.ד. 4060, תל אביב ריינהולד כהן ושותפיו, רחוב אחד העם 21 ת, [57] A micelle-forming composition, selected from the group consisting of poly comprised of: a hydrophobic core (glycolic acid), poly (lactic acid), poly (Dlactic acid), poly (D, L-lactic acid), surrounded by a hydrophilic shell; and a therapeutic agent physically entrapped lactide/glycolide copolymers or within said micelle; wherein the polycaprolactone and derivatives thereof; hydrophobic core is selected from the and the hydrophilic shell is poly (N-vinylgroup consisting of a polyorthoester, a 2-pyrrolidone); said composition being polyanhydride, a tyrosine derived pseudopoly (amino acid), a polyphosphazene or a following addition of an aqueous solution readily redispersed or redissolved poly (β-benzyl-l-aspartate) and to a freeze-dried form of the micelleforming composition. combinations thereof, or a polyester BONE GRAFT COMPOSITE Int. Cl.8 A61K 047/02 PROCHON LTD. WEBB & ASSOCIATES, 2 PEKERIS ST., P.O.B. 2189, REHOVOT הרכב להשתלה בעצם פרוכון בע"מ, נס-ציונה ד"ר וב ושות', רח' פקריס, 2 ת.ד. 2189, רחובות [57] A bone graft composite comprising a synthetic apatite, at least one amino acid in monomeric or polymeric form, a carbonate and at least one anti-resorptive agent, wherein the at least one anti-resorptive agent is introduced into the composite ab initio. 2710

209 APPARATUS AND PROCESSES FOR IODINE DISINFECTION OF WATER מתקנים ותהליכים לחיטוי של מים ע"י יוד [31] [87] PQ8916 [32] Int. Cl.8 C01B 007/14, C02F 001/50 IODINE TECHNOLOGIES AUSTRALIA PTY LTD., AUSTRALIA WO/2002/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] AU סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] An apparatus for iodine decontamination and purification of a water stream, the apparatus comprising: a source of water for one or more water consuming applications and for providing a water stream; a delivery station intermediate said source of water and a treatment station; a source of iodine at the delivery station; means to enable release into said water stream of said iodine; a monitoring electrode associated with the delivery station which maintains the iodine in said water stream at a predetermined concentration to provide a predetermined level of purification of said water stream and/or objects in contact with said water stream in the treatment station; means for recovery from said water stream of said iodine and/or iodide and/or other iodine species derived from said iodine; and means for conversion of all said recovered iodine species derived from said iodine delivered to said stream to iodine as used in this system. SYSTEM AND METHOD FOR PULVERIZING STONES AND FOR SCAR REMOVAL IN SOFT TISSUES Int. Cl.8 A61B 017/22 SIALO-LITE LTD. REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV מערכת ושיטה לריסוק אבנים והסרת צלקות ברקמות רכות סיאלו-לייט בע"מ, אשקלון ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב 2711

210 [57] A system for treatment of hard tissues present in a fluid-filled body cavity the cavity having a diameter of 3 mm or less, said system comprising: (a) an endoscope for visualizing the interior of said cavity; (b) an erbium laser device adapted to generate a laser beam configured to pulverize the hard tissue; and (c) an optic fiber (136) for delivering the laser beam to the hard tissue or to the vicinity of the hard tissue VAGINAL DELIVERY OF BISPHOSPHONATES מתן וגינלי של ביספוספונטים [31] [87] / [32] [33] US Int. Cl.8 A61F 013/00, A61K 009/02, C07F 009/38 UMD, INC., U.S.A. WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] Use of a transmucosal vaginal to about 2000 mg of the bisphosphonate composition of bisphosphonates in the selected from the group consisting of preparation of a medicament for treatment alendronate, clodronate, etidronate, and prevention of osteoporosis and Paget's pamidronate, tiludronate, ibandronate, disease and for treatment of a metastatic neridronate, risedronate, zoledronate and bone disease in a human female patient, olpadronate; from about 40 to about 95% wherein a bisphosphonate is delivered into of a saturated mono-, di- or triglyceride of the systemic circulation through a vaginal fatty acids from 8 to 18 carbons or a mucosa from a vaginal device incorporated mixture thereof; from about 5 to about with a transmucosal vaginal composition, 25% of a mucoadhesive agent selected said use comprising steps of: providing the from the group consisting of alginate, transmucosal vaginal composition pectin and a cellulose derivative; and from consisting essentially of from about about 5 to about 25% of 2712

211 ethoxydiglycol; wherein said composition microcapsules; and wherein said is formulated and incorporated into the composition is used via a vaginal tampon, device as a suppository, cream, gel, foam, vaginal ring, vaginal strip, vaginal capsule, ointment, capsule containing vaginal tablet, vaginal pessary, vaginal cup microparticles, microparticles or or vaginal sponge [31] [87] ABRASIVE PRODUCT /3920 [32] / Int. Cl.8 B24D 003/04 ELEMENT SIX (PTY) LTD., SOUTH AFRICA WO/2002/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA [33] ZA ZA מוצר משפשף לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] An abrasive product comprising a plastic deformation of the abrasive polycrystalline mass of self-bonded ultrahard abrasive particles of irregular shape, least 0.3 percent, and having a porosity particles, such plastic deformation being at the product being substantially free of a which is greater than 10 percent by volume second phase, containing substantial and does not exceed 25 percent by volume. 2713

212 USE OF 5 METHYL 2- (2' CHLORO 6' FLUOROANILINO) PHENYLACETIC ACID OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF IN THE MANUFACTURE OF A MEDICAMENT FOR TREATING CYCLOOXYGENASE 2 DEPENDENT DISORDER AND A MEDICAMENT PACKAGE COMPRISING THE SAME שימוש ב 5 מתיל 2 2') כלורו '6 פלואורואנילינו) חומצה פנילאצטית או מלח רוקחי מקובל שלו לייצור תרופה לטיפול באי סדר הקשור לציקלואוקסיגנז 2 ואריזה לתרופה המכילה אותם [31] [87] / [32] [33] US 60/ US Int. Cl.8 A61K 031/196, A61P 029/00, 043/00, C07C 229/42 NOVARTIS AG, SWITZERLAND WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] Use of 5-methyl-2-(2'-chloro-6'- treating a cyclooxygenase-2 dependent fluoroanilino) phenylacetic acid or a disorder or condition wherein the pharmaceutically acceptable salt thereof in medicament is for once daily the manufacture of a medicament for administration. 2714

213 [31] [87] METHOD AND SYSTEM FOR REAL-TIME FLUORESCENT DETERMINATION OF TRACE ELEMENTS / [32] Int. Cl.8 G01N 023/00 GLAXO GROUP LIMITED, UNITED KINGDOM WO/2002/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV שיטה ומערכת למדידות פלורוסנציה של יסודות עקבות בזמן אמת [33] US ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A system for use in in-situ analysis of pharmaceutical samples (14), said system comprising: means (10a, 10b) for holding a plurality of said samples, wherein said samples are present in the form of a Metered Dry Powder Inhaler formulation; means (50) for moving said plurality of samples along a sample path; means (26) for generating a plurality of incident radiation pulses of different wavelength; means (22) for illuminating at least a respective one of said samples with at least a respective one of said radiation pulses during said movement of said samples, said radiation pulse having a suitable range of radiation wavelengths capable of inducing a fluorescent response; means (20) for detecting a first resultant fluorescence emitted from each of said samples; first control means (24) in communication with said moving means and said incident radiation generating means for synchronizing said means for illuminating each of said samples with said moving means. 2715

214 METHOD FOR PRODUCING β- KETOENOL ESTERS שיטה ליצור β קטואנול אסטרים [31] [87] [32] [33] DE Int. Cl.8 C07C 045/67, 067/00, 067/36, 069/76, C07D 261/04, 275/06 BASF AKTIENGESELLSCHAFT, GERMANY WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A process for preparing β-ketoenol esters of the formulae in which 5- or 6-membered saturated carbocycle, a R a, R b independently of one another are spiro-linked 3-, 4-, 5- or 6- or 7-membered C 1 -C 6 -alkyl or C 3 -C 8 -cycloalkyl, or R a and saturated carbocycle, a spiro-linked 3-, 4-, R b together are C 2 -C 4 -alkanediyl or C 5 -C 7-5-, 6- or 7-membered saturated heterocycle cycloalkanediyl, where the three groups having 1 or 2 chalkogen atoms, selected mentioned above may be substituted or from the group consisting of oxygen and unsubstituted and may have a fused 3-, 4-, sulfur and/or a carbonyl or thiocarbonyl 2716

215 group; Ar is phenyl or pyridyl, which may in each case have 1, 2, 3 or 4 substituents, it also being possible for two substituents attached to adjacent carbon atoms to form, together with these atoms, a 5- or 6- membered saturated or unsaturated carbocycle or a 5- or 6-membered saturated or unsaturated heterocycle which has 1, 2 or 3 hetero atoms selected from the group consisting of O, N and S and which for its part may be substituted or unsubstituted; which comprises reacting an aryl halide of the formula Ar-Hal in which Hal is bromine with a 1, 3- diketone or its tautomer of the formula in a carbon monoxide atmosphere in the presence of a base and a catalyst which comprises at least one transition metal of group VIII of the Periodic Table of the Elements [31] [72] [87] 3D IMAGE PROCESSING ADEQUATE FOR SYSTEM WITHOUT HARDWARE SUPPORT [32] Int. Cl.8 G06T 003/00, 015/00 HI CORPORATION, JAPAN YASUHISA TANIOKA, JUNYA TSUTSUMI, KAZUO KAWABATA, KAZUTOSHI ODA WO/2003/ DR. MARK FRIEDMAN LTD., MOSHE AVIV TOWER, 54TH FLOOR, 7 JABOTINSKY ST., RAMAT GAN [33] עיבוד הדמייה תלת מימדי מתאים למערכות ללא תמיכת חומרה JP ד"ר מרק פרידמן בע"מ, מגדל משה אביב, ק. 54, רח ז'בוטינסקי 7, רמת- גן [57] An information processing apparatus for, in conducting Rasterize processing of imaging of a three-dimensional image, calculating a quantity of a change of x coordinates 2717

216 to y coordinates of a straight line passing through a point P 1 (x 1, y 1 ) and a point P 2 (x 2, y 2 ) on a two-dimensional plane, characterized in that the apparatus comprises: a memory in which a constant µ representative of is stored in association with the quantity of the change of the y coordinates; and calculation means for, in calculating x, reading µ corresponding to the quantity of the change of said y coordinates from said memory, and calculating by means of multiplication, and calculating this result as x. 2718

217 [87] TIMING-SENSITIVE GLITCH- FREE LOGIC SYSTEM AND METHOD Int. Cl.8 G06F 009/455, 011/36, 017/50 VERISITY DESIGN, INC., U.S.A. WO/2003/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM מערכת ושיטה לוגית שאינה רגישת-זמן וחופשיה מהפרעה אקראית וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים [57] A debug system for verifying the proper operation of a user design circuit, the user design containing logic devices and circuit paths, comprising: a computing system that generates a software model of the user design circuit; a reconfigurable hardware system that generates a hardware model of at least a portion of the user design circuit; and control means serving as a slave to the computing system and coupled to the computing system and the reconfigurable hardware system for controlling the operation of the hardware model in the reconfigurable hardware system. 2719

218 [72] APPARATUS FOR CHECKING DEVIATION FROM CONCENTRICITY Int. Cl.8 B23B 049/00, G01B 005/20 TECHNOTOOL GOLDMAN ISRAEL LTD. ISRAEL GOLDMAN PEARL COHEN ZEDEK LATZER, 5 SHENKAR ST., P.O.B , HERZLIYA מתקן לבדיקת סטיה מקונצנטריות טוכנוטול גולדמן ישראל בע"מ, נהריה ישראל גולדמן פרל כהן צדק לצר, מרכז גב- םי 1, רח' שנקר, 5 ת.ד , הרצליה [57] An apparatus for checking deviation in the shape of a part (18) having a portion which has supposedly rotational symmetry about an axis and having a reference end face (20), comprising: a base (10); a support arrangement (14) mounted on said base for receiving said portion and comprising two V-blocks; a positioning arrangement (16) for positioning said part axially with respect to said reference end face; and a driving mechanism for driving said part in rotation about said axis, wherein said positioning arrangement comprises: a rectilinear portion with an end for providing an abutment for said reference end face, said rectilinear portion slidably mounted on said base, adjustable along three axes and rotatable about at least one of said three axes. 2720

219 [31] [87] SYSTEM AND METHOD FOR SECURED DUAL CHANNEL COMMUNICATION THROUGH A FIREWALL / [32] Int. Cl.8 G06F 002/ H04L 009/00 STERLING COMMERCE, INC., U.S.A. WO/2002/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA [33] שיטה ומערכת לתקשורת דו כיוונית מאובטחת באמצעות FIREWALL US לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] A method for establishing a data socket between a server and a client, comprising: encoding a port command including a client internal IP address and a client port number; generating a dual channel communication packet having a header and data payload, the header including a server external IP address, server port number, the client internal IP address and the client port number; the data payload including the encoded port command; transmitting the communication packet between the server and the client; decoding the port command; retrieving the client external IP address from the header; modifying the decoded port command by overriding the client internal IP address within the decoded port command with the client external IP address retrieved from the header; and establishing a data socket between the server and the client using the modified decoded port command. 2721

220 PURINE RIBOSIDES AS ANTIARRHYTHMICS פורין ריבוסידים כחומרים נגד אי קצב [31] [87] / [32] [33] US 60/ US Int. Cl.8 A61K 031/7076, A61P 009/06, C07H 019/167 CV THERAPEUTICS, INC., U.S.A. WO/2002/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] Use of a therapeutically effective minimal dose of an adenosine A 1 receptor agonist of the formula wherein: said minimal dose is in the range of R 1 is an optionally substituted heterocyclic mg/kg, for the preparation of group; and a pharmaceutical composition for treating arrhythmia in a mammal. 2722

221 [31] [87] PHARMACEUTICAL HYDROPHILIC GEL FORMING MATRIX FORMULATION HAVING PROLONGED RELEASE AND METHOD FOR ITS PREPARATION [32] Int. Cl.8 A61K 009/00, 009/22, 047/36 SOLVAY PHARMACEUTICALS B.V., THE NETHERLANDS WO/2002/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV הכנה רוקחית בצורת ג'ל הידרופילי יוצר מטריצה לשחרור מושהה ושיטה להכנתו [33] NL EP ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A pharmaceutical hydrophilic gel forming matrix formation comprising one or more active substances and having a prolonged release of said one or more active substances upon exposure to gastrointestinal fluids, characterized in that said pharmaceutical formulation comprises high or medium viscosity hydroxypropylmethylcellulose (HPMC) and a high or medium viscosity hydroxyethylcellulose (HEC), in a ratio HPMC/HEC = 1/0.85 1/1.2 and optionally a low viscosity HPMC in a ratio high or medium viscosity HPMC/low viscosity HPMC=1/0.01-1/

222 USE OF DISTAMYCIN DERIVATIVES FOR THE PREPARATION OF MEDICAMENTS FOR TREATING TUMORS שימוש בתודות דיסטאמיצין להכנת תרופות לטיפול בגידולים ממאירים [31] [87] / [32] [33] US Int. Cl.8 A61K 031/40, 035/00, C07D 207/34, 403/14 PHARMACIA & UPJOHN COMPANY LLC, U.S.A. PFIZER ITALIA S.R.L., ITALY WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Use of an α-halogen-acryloyl distamycin derivative of the formula wherein: R is a bromine or chlorine atom; or a pharmaceutically acceptable salt thereof; in the preparation of a medicament for the treatment of tumors by a schedule comprising the intravenous infusion of the medicament as a single administration every three or four weeks in an amount of from 0.85 mg/m 2 to 20 mg/m 2 of body surface area, or weekly for three consecutive weeks every four or five weeks in an amount from 0.3 mg/m 2 /week to 7 mg/m 2 /week. 2724

223 COVER FOR DRAINS, PIPE ENDS AND THE LIKE Int. Cl.7 E03C 001/26, F16L 055/12 GILI PEERY REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV מכסה לצינורות ניקוז, לקצוות צינורות ודומיהם גילי פארי, פרדסיה ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A closure device for a pipe end comprising: a ring member (30) adapted for press fitting within said pipe end and having a sealing surface (32); and a cover member (20) having a peripheral surface of a diameter larger than that of the pipe end, said cover member suited for abutment against a floor surface (90) and against at least one of said sealing surface and an end surface (37) of said pipe end; said cover member and said ring member comprising suitable rotatable engagement means (40) for enabling said cover member to be rotatably engaged with respect to said ring member. 2725

224 TRANSFER OF DATA IN A TELECOMMUNICATIONS SYSTEM העברת נתונים במערכת טלקומוניקציה [31] [87] [32] [33] GB Int. Cl.8 H04B 007/26, H04J 013/00, H04L 001/00 AIRSPAN NETWORKS INC., U.S.A. WO/2002/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] A method of operating a telecommunications system to route data messages between a network and subscriber terminals of the telecommunications system, the subscriber terminals being connectable to a central terminal of the telecommunications system via a transmission medium, the telecommunications system providing a number of communication channels arranged to utilize the transmission medium for transmission of data between the central terminal and the subscriber terminals, the method comprising the steps of: transmitting the data message destined for a particular subscriber terminal from the central terminal over at least one of the communication channels as a number of data blocks; and generating a number of frames to represent each data block to be transmitted, each frame having a header portion and a data portion, the header portion being arranged to be transmitted in a fixed format chosen to facilitate reception of the header portion by each subscriber terminal and being arranged to include a number of control fields for providing information about the data portion, said information comprising at least an indication of the subscriber terminal for which the corresponding data portion of the frame is destined, the data portion being arranged to be transmitted in a variable format selected based on predetermined criteria relevant to the particular subscriber terminal to which the data portion is destined; wherein the predetermined criteria comprises an indication of the signal-to-noise ratio (SNR) of signals received by the particular subscriber terminal from the central terminal, and if there are a plurality of formats selectable as the variable format given the indicated signal-to-noise ratio and the amount of data to be sent in the data block, then selecting in the frame generator from those plurality of formats the format requiring lowest transmission power. 2726

225 PROCESS FOR PRODUCING FLUORINATED METHYL- BENZYL ALCOHOL תהליך ליצירת כוהל מתיל בנזיל מפלואור [31] [87] [32] / Int. Cl.8 C07C 029/60, 031/00 SHOWA DENKO K.K., JAPAN WO/2002/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] JP US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A process for producing a fluorinated methyl-benzyl alcohol of the formula (wherein m represents an integer of 0 to 3, n represents an integer of 1 to 4, and m+n is an integer of 1 to 4), which process comprises hydrogenolysis of one hydroxyl group in a fluorinated benzene dimethanol of the formula 2727

226 (wherein m and n are the same as above). DROPLET DEPOSITION APPARATUS, COMPONENT AND METHOD OF FORMING SAME התקן להגשת טיפונת, רכיב שלו ושיטה לייצורו [31] [87] [32] Int. Cl.8 B41J 002/14, 002/16 XAAR TECHNOLOGY LIMITED, UNITED KINGDOM WO/2002/ EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] GB GB איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] Method of forming a droplet deposition apparatus comprising the steps: forming a substrate having one or more electrically conductive tracks, forming a body of piezoelectric material having a top surface and a bottom surface, providing one or more electrically conductive points on the bottom surface of said piezoelectric material comprising forming one or more depressions in said bottom surface of said piezoelectric material, locating a coating of conductive material in said depressions and further comprising subsequently filling said one or more depressions with a nonconductive material; attaching said body of piezoelectric material to said substrate with said bottom surface overlying said tracks and said electrically conductive points establishing electrical connection with said tracks for actuation of the piezoelectric material, and subsequently forming in said attached piezoelectric material at least one droplet ejection chamber. 2728

227 PROCESS FOR PRODUCTION OF AN ABSORBING SANITARY ARTICLE COMPRISING LACTIC ACID PRODUCING BACTERIA תהליך להכנת מוצר סינטרי סופג המכיל חיידק המייצר חומצת חלב [31] [87] [32] Int. Cl.8 A61F 013/15, A61L 015/36 ELLEN AB, SWEDEN WO/2002/ EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] SE איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] A process for the production of an absorbing sanitary article comprising lactic acid producing bacteria characterized in that it comprises the following steps: dispersion of viable lactic acid producing bacteria in an essentially hydrophobic carrier, resulting in a dispersion of bacteria, application of the dispersion of bacteria by continuous or discontinuous extrusion on and/or in at least one component that are to form part of the final article, providing at least one continuous and/or discontinuous string of dispersion of bacteria on and/or in the final sanitary article. 2729

228 PIPERIDINE DERIVATIVES, PROCESS FOR THEIR PREPARATION, PHARMACEUTICAL COMPOSITIONS CONTAINING THEM AND USE THEREOF IN THE PREPARATION OF MEDICAMENTS FOR THE TREATMENT OF TACHYKININ MEDIATED CONDITIONS תולדות פיפרידין, תהליך להכנתן, תכשירי רוקחות המכילים אותן ושימושן בהכנת תרופות לטיפול בתנאים הקשורים לטקיקינין [31] [87] [32] [33] GB Int. Cl.8 A61K 031/495, A61P 025/00, 043/00, C07D 401/04 GLAXO GROUP LIMITED, UNITED KINGDOM WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A compound of the formula wherein R represents a halogen atom or a C 1-4 alkyl group; R 1 represents a C 1-4 alkyl group; R 2 represents hydrogen or a C 1-4 alkyl group; R 3 represents hydrogen or C 1-4 alkyl group; R 4 represents a trifluoromethyl group; R 5 represents hydrogen, a C 1-4 alkyl group or C 1-4 alkyl group or C(O)R 6 ; R 6 represents C 1-4 alkyl, C 3-7 cycloalkyl, NH(C 1-4 alkyl) or N(C 1-4 alkyl) 2 ; m is zero or an integer from 1 to 3; n is an integer from 1 to 3; and pharmaceutically acceptable salts and solvates thereof. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. 2730

229 [31] [87] PROCESS FOR THE MANUFACTURE OF THIAZOLE DERIVATIVES WITH PESTICIDAL ACTIVITY /00 [32] Int. Cl.8 C07D 277/32, 417/06 SYNGENTA PARTICIPATIONS AG, SWITZERLAND WO/2002/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA [33] תהליך לייצור נגזרות של תיאזול עם פעילות כקוטלי מזיקים CH לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] A process for the preparation of a compound of the formula and optionally its E/Z-isomers, E/Z-isomer mixtures and/or tautomers, in each case in free form or in salt form, in which Q is CH or N; Y is NO 2 or CN; Z is CHR 3, O, NR 3 or S; R 1 and R 2 are either, independently of one another, hydrogen, unsubstituted or R 4 - substituted C 1 -C 8 alkyl, or together are an alkylene bridge having two or three carbon atoms which optionally comprises a heteroatom chosen from the group consisting of NR 5, O and S, R 3 is H or unsubstituted or R 4 -substituted C 1 -C 12 alkyl, R 4 is unsubstituted or substituted aryl or heteroaryl, and R 5 is H or C 1 -C 12 alkyl; in which (a) a compound of the formula which is known or can be prepared by known methods, and in which X is a leaving group, is reacted with a chlorinating agent to give a compound of the formula 2731

230 or optionally a tautomer, in each case in free form or in salt form; and (b) the resulting compound of the formula (III) is reacted with a compound of the formula in which R 1, R 2, Y, Z and Q have the meanings given above for the compound of the formula (I); wherein the preparation of the compound of the formula (III) according to process stage (a) involves a purification step in which the crude product which has formed is treated with aqueous hydrochloric acid. PROCESS FOR THE HYDROCYANATION OF ORGANIC COMPOUNDS COMPRISING ETHYLENIC UNSATURATION תהליך להידרוציאנציה של תרכובות אורגניות המורכבות מאנסטורציה אתילנית [31] [87] /13152 [32] [33] FR Int. Cl.8 C07C 253/10, 255/03, 255/04, 255/07 RHODIA POLYAMIDE INTERMEDIATES, FRANCE WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] Process for the hydrocyanation of organic compounds comprising at least one ethylenic bond by reaction with hydrogen cyanide in the presence of a catalytic system comprising a transition metal and an organophosphorus ligand, characterized in that the ligand is a phosphine of the formula 2732

231 in which: E represents O or S; n represents 0 or 1; R 1, R 4, R 5 and R 6, which are identical or different, represent a hydrogen atom; or else a T radical chosen from: a saturated or unsaturated, aliphatic hydrocarbonaceous radical comprising 1 to 40 carbon atoms, the hydrocarbonaceous chain of which is optionally interrupted by a heteroatom; a monocyclic or polycyclic, saturated, unsaturated or aromatic, carbocyclic or heterocyclic radical; or a saturated or unsaturated, aliphatic hydrocarbonaceous radical, the hydrocarbonaceous chain of which is optionally interrupted by a heteroatom and carries a carbocyclic or heterocyclic radical as defined above; or else R 4 and R 5 form, together with the carbon atoms which carry them, a saturated or unsaturated, carbocyclic monocycle preferably having from 5 to 7 carbon atoms; R 2 represents a hydrogen atom or the X radical; R 3 represents the X radical or the Y radical; it being understood that one and one alone of the R 2 and R 3 substituents represents the X radical; X being chosen from a monocyclic or bicyclic, aromatic carbocyclic or heterocyclic radical having from 2 to 20 carbon atoms; a 1-alkenyl radical optionally exhibiting one or more additional unsaturations in the hydrocarbonaceous chain and having from 2 to 12 carbon atoms; a 1-alkynyl radical optionally exhibiting one or more additional unsaturations in the hydrocarbonaceous chain and having from 2 to 12 carbon atoms; or a CN, [(C 1 -C 12 ) alkyl] carbonyl, [(C 3 -C 18 ) aryl] carbonyl, [(C 1 -C 12 ) alkoxy] carbonyl, [(C 6 -C 18 ) aryloxy] carbonyl, carbamoyl, [(C 1 -C 12 ) alkyl]] carbamoyl or [di(c 1 -C 12 ) alkyl] carbamoyl radical; and Y taking any one of the meanings of R 1, with the exception of a hydrogen atom; R 7 has the meaning of R 1, R 4, R 5 and R 6 or represents a hydrocarbonaceous radical comprising a carbonyl functional group or a radical of the formulae in which, A represents a hydrogen atom; (C 1 -C 10 ) alkyl; or (C 6 -C 10 ) aryl or (C 6 -C 10 ) aryl (C 1 - C 10 ) alkyl in which the aryl part is optionally substituted by one or more radicals chosen from (C 1 -C 6 ) alkyl, (C 1 -C 6 ) 2733 alkoxy, trifluoromethyl, halogen, di (C 1 - C 6 ) alkylamino, (C 1 -C 6 ) alkoxycarbonyl, carbamoyl, (C 1 -C 6 ) alkylaminocarbonyl and di (C 1 -C 6 ) alkylaminocarbonyl; -Ar 1 -Ar 2 - represent: either the divalent radical of formula:

232 in which each of the phenyl nuclei is optionally substituted by one or more Z groups as defined below; or the divalent radical of formula: in which each of the phenyl nuclei is optionally substituted by one or more Z groups as defined below; Z represents (C 1 - C 6 ) alkyl, (C 1 -C 6 ) alkoxy, trifluoromethyl, halogen, (C 1 -C 6 ) alkoxycarbonyl, di (C 1 - C 6 ) alkylamino, (C 1 -C 6 ) alkylaminocarbonyl or di (C 1 -C 6 ) alkylaminocarbonyl; R 8 and R 9, which are identical or different, represent an aryl radical FAN TYPE CHEMICAL DISPERSION EQUIPMENT ציוד דמוי מאוורר לדיספרסיה כימית [31] [87] [32] Int. Cl.8 A01M 001/20 FUMAKILLA LIMITED, JAPAN WO/2002/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] JP JP JP JP ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב

233 [57] A fan type chemical diffusing apparatus, characterized in that it comprises: a chemical receptacle (3) for accommodating a chemical impregnated body (10) therein that is impregnated with a chemical, the chemical receptacle having vent holes (9); a chemical receptacle retainer (4) for holding said chemical receptacle; a power supply housing (11) for receiving power supply therein, said power supply powering a motor (30); and an apparatus main body (1) including a fan (32) for producing an airflow, said motor for driving the fan, a switch for turning on and off current conduction to said motor, an inner airflow opening (24) and an outer air flow opening (28) disposed in a front face and a side face of said apparatus main body, respectively, for permitting the airflow produced by said fan to pass therethrough, a recessed portion formed in from a front side to a lower side of said apparatus main body, which can be loaded with said chemical receptacle retainer and said power supply housing, and an electric connector (36) which when said power supply housing is loaded into a lower portion of said recessed portion of said apparatus main body is brought into contact with said power supply received in said power supply housing to establish electric connection between said power supply and said switch; wherein said chemical receptacle retainer and said power supply housing are adapted to be detachably loaded in a front portion and the lower portion of said recessed portion of said apparatus main body, respectively and when loaded are each positioned therein so as to receive essentially no limitation in volume from the other. 2735

234 CIVIL AVIATION PASSIVE COHERENT LOCATION SYSTEM AND METHOD מערכת ושיטה לאיכון פסיבי בתעופה אזרחית [31] [72] [87] / [32] / Int. Cl.8 G01S 005/12 LOCKHEED MARTIN CORPORATION, U.S.A. ROBERT BENNER, KEVIN W. BAUGH, RICHARD LODWIG WO/2002/ SOROKER-AGMON, 14 SHENKAR ST., HERZLIYA PITUAH [33] US US סורוקר-אגמון, בית נולטון, רחוב שנקר 14, הרצליה פיתוח [57] A system for enhancing object state awareness to track a plurality of approaching airborne objects, comprising: a receiver subsystem (220) to receive reference signals from an uncontrolled transmitter and scattered transmission originating from the uncontrolled transmitter and scattered by an object of approaching airborne objects; a front-end processing subsystem (230) to determine a radial velocity of the object based on the received transmissions and to buffer digitized transmission replicas of the received transmissions; and a backprocessing subsystem (240) to receive the digitized transmission replicas of the received transmissions and to determine object state estimates based on the determined radial velocity, wherein said front-end processing subsystem and said back-end processing subsystem are remotely located relative to one another. 2736

235 INHALATIVE SOLUTION FORMULATION CONTAINING A TIOTROPIUM SALT הרכב תמיסה להשאפה המכיל מלח טיאוטרופיום [31] [87] [32] [33] DE Int. Cl.8 A61K 009/00, 009/72, A61P 011/00, C07D 451/00 BOEHRINGER INGELHEIM PHARMA GMBH & CO. KG, GERMANY WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Propellant-free pharmaceutical preparation for administration by inhalation comprising a tiotropium salt as active substance, in a concentration based on tiotropium of between and 5% by weight, water on its own or water/ethanol mixture as solvent for the active substance, acid for achieving a ph between 2.0 and 3.1, a pharmacologically 2737 acceptable preservative, optionally editic acid or an editic acid salt in an amount of greater than 0 up to 25 mg/100 ml, optionally a pharmacologically acceptable complexing agent and/or stabilizer and/or a pharmacologically acceptable cosolvent and/or other pharmacologically acceptable adjuvants and additives in addition to the preservative.

236 PYRIMIDINE DERIVATIVES AND PHARMACEUTICALLY ACCEPTABLE ACID ADDITION SALTS THEREOF נגזרות של פירימידין ותוסף חומצת מלח רוקחי מתאים [31] [87] [32] [33] EP Int. Cl.8 A61K 031/495, 031/5377, 031/5395, C07D 239/46, 401/04, 401/12, 403/04, 413/04, 413/12 F. HOFFMANN-LA ROCHE AG, SWITZERLAND WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A compound of the formula: wherein R 1 is lower alkyl, lower alkoxy, pyridinyl, pyrimidinyl, phenyl, --S- lower alkyl -- S(O) 2 lower alkyl, --N(R a )--(CH 2 ) n -- N(R b ) 2, --O--(CH 2 ) n --N(R b ) 2, --O--(CH 2 ) n --N(R c ) 2, --N(R d ) 2, or a cyclic tertiary amine of the group having no or one additional heteroatom, connected to said pyrimidine ring of selected from N, O or S, said cyclic formula 1 via the linker - -O(CH 2 ) n --; tertiary amine being connected directly to R 2 is hydrogen, lower alkyl, lower alkoxy, a pyrimidine ring of formula 1 or halogen or trifluoromethyl; 2738

237 R 3 /R 3 ' are, independently from each other, hydrogen or lower alkyl; (R 4 ) m are, independently from each other in the case where m is not 0 or 1, halogen, trifluoromethyl or lower alkoxy; R 5 is hydrogen or lower alkyl; R, R a, R b, R c, R d, R e, R f are, independently from each other, hydrogen or lower alkyl; X is N(R f C(O)--; Y is --O--, --S--, --SO 2 --, - or --N(R)--; n is 1, 2, 3 or 4; and m is 0, 1 or 2; or a pharmaceutically acceptable acid addition salt thereof. MEDICAMENTS COMPRISING 5 (R) 2 (5, 6 DIETHYL INDEN 2 YLAMINO) 1 HYDROXY ETHYL] 8 HYDROXY 1H QUINOLIN 2 ONE AND CORTICOSTEROIDS FOR TREATING AIRWAY DISEASES תרופות המכילות 5 5] (6, 2 (R) דיאתיל אינדן 2 אילמינו) 1 הידרוקסיאתיל] 8 הידרוקסי H1 קווינולין 2 און וקורטיקוסטרואידים לטיפול במחלות בדרכי הנשימה [31] [87] [32] [33] GB Int. Cl.8 A61K 031/4704, 031/57, 031/573, 031/575, A61P 011/00, C07D 215/227, C07J 007/00, 009/00 NOVARTIS AG, SWITZERLAND WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] Medicament comprising, separately or together, (A) a compound of formula in free or pharmaceutically acceptable salt or solvate form and (B) a corticosteroid, for simultaneous, sequential or separate administration in the treatment of an inflammatory or obstructive airways disease, the molar ratio of (A) to (B) being from 100:1 to 1:

238 ATORVASTATIN HEMI- CALCIUM FORM VII פורם 7 של אטורווסטטין המיקלציום [31] [87] / [32] [33] US Int. Cl.8 A61K 031/40, A61P 003/06, C07D 207/34 TEVA PHARMACEUTICAL טבע תעשיות פרמצבטיות בע"מ, פתח INDUSTRIES LTD. תקווה WO/2002/ TEVA PHARMACEUTICAL טבע תעשיות פרמצבטיות בע"מ, INDUSTRIES LTD., 5 BASEL ST., P.O.B. 3190,, 5 ת.ד. 3190, פתח תקוה בזל PETAH TIQVA [57] Atorvastatin hemi-calcium Form VII or a hydrate thereof characterized by a powder X-ray diffraction pattern having broad peaks in the range of and degrees two-theta SINGLE USER DETECTION זיהוי משתמש יחיד [31] [87] / [32] [33] US Int. Cl.8 H04B 001/707, 007/216, H04Q 007/38 INTERDIGITAL TECHNOLOGY CORPORATION, U.S.A. WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A method for use in receiving a plurality of data signals transmitted from a transmitter site over a shared spectrum in a code division multiple access communication system, each transmitted data signal experiencing a similar channel response, the method comprising: receiving a combined signal of the transmitted data signals over the shared spectrum; sampling the combined signal at a multiple of a chip rate of the transmitted data signals; estimating a channel response for the combined signal at the multiple of the chip rate; determining a first element of a spread data vector using the combined signal samples and the estimated channel response; using a factor from the first element determination to determine remaining elements of the spread data vector; and estimating data of the data signals using the determined elements of the spread data vector. 2740

239 The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו MODULATOR FOR ELECTROMAGNETIC SIGNALS TRANSMITTED BY A CONTACTLESS TRANSMISSION/RECEPTION SYSTEM מאפנן לאותות אלקטרומגנטיים המועברים על ידי מערכת קולטת/משדרת ללא מגע [31] [87] /11917 [32] Int. Cl.8 H04L 027/00 ASK S.A., FRANCE WO/2003/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] FR ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A transmission device using electromagnetic wave radiation (20) in a contactless transceiver system toward a contactless object, data bits transmitted corresponding to alternation of a first time interval during which electromagnetic waves are emitted at a predetermined carrier frequency and a second splitting time interval during which there is a split in transmission of the electromagnetic waves at said predetermined carrier frequency, further comprising generating means for generating, during said second splitting time interval, electromagnetic waves with a frequency greater than the fundamental frequency of the split resulting in an attenuation of the radiated field by the antenna greater than a predetermined value. 2741

240 SYSTEM AND METHOD OF DESKEW BUFFERING SIGNALS מערכת ושיטה של מנחת דיסקוו של סגנלים [31] [87] / [32] Int. Cl.8 H04B 001/707 QUALCOMM INCORPORATED, U.S.A. WO/2002/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A method of deskew buffering a CDMA signal comprising: demodulating an earliest arriving signal to extract an earliest arriving symbol in a multirate system having a plurality of Walsh code lengths, aligning the earliest arriving symbol to a deskew buffer address using a PN count value; modifying the deskew buffer address; and writing the earliest arriving symbol into the modified deskew buffer address. 2742

241 METHOD AND SYSTEM FOR ONLINE PAYMENTS שיטה ומערכת לתשלומים בזמן אמת [31] [87] / [32] [33] US Int. Cl.8 G06F 003/033, G06Q 003/00000 SILVERBROOK RESEARCH PTY. LTD., AUSTRALIA WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A method of enabling payment of bills, the method including the steps of providing a person with a bill containing information relating to a requested payment, the bill including a plurality of coded tags, each coded tag encoding data indicative of an identity of the bill and a position of that tag on the bill; receiving, in a computer system indicating data from a sensing device, the sensing device, when placed in an operative position relative to the bill, sensing the coded tags and generating the indicating data to 2743 indicate the identity of the bill and a position of the sensing device relative to the sensed coded tags; and identifying, in the computer system and from the indicating data, at least one parameter relating to the requested payment from a digital description of the bill associated with the identify of the bill, the at least one parameter being associated in said digital description with the corresponding tag locations on the bill.

242 METHOD AND SYSTEM FOR ONLINE PURCHASING שיטה ומערכת לקניה מקוונת [31] [87] / [32] [33] US Int. Cl.8 G06F 003/033, G06Q 003/00000 SILVERBROOK RESEARCH PTY. LTD., AUSTRALIA WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A method of enabling online purchasing via a form printed on a substrate, said form including graphical purchasing information and a plurality of tags, each tag comprising coded data identifying the form and its own location on the form, the method including the steps of: (a) determining a unique page identity for said form in a computer system before printing said form; (b) determining a page description for said form in said computer system before printing said form, said page description comprising a description of graphical information on said form, and a description of an interactive element including a zone of said interactive element on said form; (c) associating said page identity with said description of said interactive element; (d) printing, on demand, the form onto 2744

243 a substrate using a printer networked with the computer system, said graphical information and said tags being printed at the same time; (e) receiving, in said computer system, indicating data from a sensing device regarding the identity of the form and a position of the sensing device relative to the form, the sensing device, when placed in an operative position relative to the form, generating the indicating data using at least some of the coded data; and (f) identifying, in the computer system and from the indicating data, at least one paramteter relating to the purchasing transaction. METHODS OF ORGANIZING DATA AND PROCESSING QUERIES IN A DATABASE SYSTEM AND DATABASE SYSTEM AND SOFTWARE PRODUCT FOR IMPLEMENTING SUCH METHOD שיטות לארגון נתונים ולעיבוד שאלות במערכת מאגר נתונים, ומערכת מאגר נתונים ומצור תוכנה ליישומן של שיטותאלו [31] [87] [32] Int. Cl.8 G06F 017/30 VIRTUAL KEY GRAPH, U.S.A WO/2002/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] EP EP EP EP סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות 2745

244 [57] A method of organizing information in a database system, wherein a group of attributes is defined and words of a collection of data are assigned to said attributes, wherein the group of attributes is divided into a plurality of sub-groups each associated with a respective data table, each data table having a column for each attribute of the associated sub-group and rows for containing data table records comprising at least one word assigned to an attribute of the associated sub-group, wherein links are defined between the data tables records, each link having a target table and a corresponding source table having a link column containing link values each designating a record of said target table, whereby each of said link values represents a link between the record of the source table including said link value and the record of the target table designated by said link value, the method comprising the steps of: allocating respective identifiers to data graphs, wherein each data graph represents related attribute values respectively assigned to the attributes of said group, wherein each attribute value of a data graph is either a default value or a work of said collection of data, and wherein the words of each data graph are from linked data table records; storing a plurality of word thesauruses respectively associated with attributes of said group, wherein for each word assigned at least once to an attribute in the collection of data, the word thesaurus associated with said attribute has a respective entry containing said word; and storing data representing data graph identifier lists respectively associated with the word thesaurus entries, wherein the data graph identifier list associated with a thesaurus entry relating to a word assigned to an attribute includes any identifier allocated to a data graph having said word assigned to said attribute. The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו FARNESYLTRANSFERASE INHIBITORS מעכבי טרנספרז של פרנזיל [31] [87] / [32] [33] US 09/ US Int. Cl.8 A61K 031/4164, 031/426, A61P 035/00, 043/00, C07D 233/64, 277/20, 401/12, 403/12, 417/12, C07F 007/10 ABBOTT LABORATORIES, U.S.A. WO/2002/ DR. SHLOMO COHEN & CO., ד"ר שלמה כהן ושות', 124 IBN GABIROL ST., P.O.B , אבן גבירול, 124 ת.ד , תל אביב TEL AVIV

245 [57] A compound of the formula or a therapeutically acceptable salt thereof, wherein E is a five-, six-, or seven-membered aromatic or non-aromatic carbocyclic ring wherein from zero to three carbon atoms are replaced by nitrogen; F and G are independently selected from the group consisting of C and N; with the proviso that when one of F and G is N, the other is C; L 1 and L 2 are each independently selected from the group consisting of a bond, C 2 alkenylene, C 2 alkynylene, O, NR 9, C(O), S, S(O), SO 2, SO 2 NR 9, NR 9 SO 2, C(O)NR 9, NR 9 C(O), and CO 2 ; X is selected from the group consisting of S and NR 7 ; R 1 is selected from the group consisting of aryl, arylalkyl, heterocycle, and (heterocycle) alkyl; R 2 is selected from the group consisting of hydrogen, alkoxy, alkyl, amino, aminoalkyl, cyano, cyanoalkyl, cycloalkyl, cycloalkylalkyl, halo, haloalkyl, heterocycle, (heterocycle) alkyl, hydroxy, and hydroxyalkyl; R 3 is selected from the group consisting of aryl, heterocycle, and cycloalkyl; R 4-6 are each independently selected from the group consisting of hydrogen, NR 9 C(O), C(O)NR 9, alkanoyl, alkenyl, alkoxy, alkoxyalkyl, alkyl, alkylsulfonyl, alkynyl, amido, amino, aminoalkyl, aminosulfonyl, aryl, arylalkyl, aryloxy, arylsulfonyl, azido, carboxy, cyano, cyanoalkyl, cycloalkyl, cycloalkyalkyl, halo, haloalkoxy, haloalkyl, heterocycle, (heterocycle) alkyl, hydroxy, hydroxyalkyl, nitro, nitroalkyl, oxo, and thio (oxo); R 7 is selected from the group consisting of hydrogen, alkyl, aryl, cycloalkyl, cycloalkyalkyl, heterocycle, (heterocycle) alkyl, and trialkylsilyl; R 9 is selected from the group consisting of hydrogen, alkoxyalkyl, alkyl, amidoalkyl, aminoalkyl, aryl, arylalkyl, cycloalkyl, cycloalkylalkyl, carboxyalkyl, heterocycle, (heterocycle) alkyl, hydroxyalkyl, and a nitrogen protecting group; each R 12 is independently selected from the group consisting of hydrogen, alkoxy, alkyl, amino, halo, and hydroxy; m is 0, 1, 2, 3 or 4; n is 0, 1, 2, 3 or 4; p is 0, 1, 2, 3 or 4; and q is 0,1, 2, 3 or

246 SYSTEM AND METHOD FOR EFFECTING HIGH-POWER BEAM CONTROL WITH OUTGOING WAVEFRONT CORRECTION UTILIZING HOLOGRAPHIC SAMPLING AT PRIMARY MIRROR, PHASE CONJUGATION, AND ADAPTIVE OPTICS IN LOW POWER BEAM PATH מערכת ושיטה לביצוע בקרת קרן בעוצמה גבוהה בעלת תיקון חזית גל יוצא באמצעות דגימה הולוגרפית במראה הראשית, הצמדת מופעים ואופטיקה מסתגלת במסלול קרן בעוצמה נמוכה [31] [87] / [32] [33] US Int. Cl.8 G01J 009/00, G02B 023/02, 026/06, H01S 003/10 RAYTHEON COMPANY, U.S.A. WO/2003/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] A beam control system (500) comprising: a telescope (510) for providing a first beam (503) of electromagnetic energy; a holographic element (518) for sampling said first beam and providing a second beam (505) in response thereto; a wavefront sensor (520) for detecting aberrations in said second beam and generating an error signal; and characterised by: an adaptive optical arrangement including; a source of a reference beam (552); a processor (580) responsive to said error signal to generate a correction signal for correcting aberrations in said first beam; an optical phased array (550) for modifying said reference beam in response to said correction signal; a first phase conjugate mirror (546); an aperture sharing element (540) disposed in alignment with said first phase conjugate mirror, wherein said modified reference beam is adapted to read a first surface of said aperture sharing element and provide a back side read beam in response thereto and said first phase conjugate mirror is adapted to conjugate the phase of said back side read beam and provide a conjugated back side read beam in response thereto; and a second phase conjugate mirror (550) adapted to conjugate the phase of said conjugated back side read beam thus cancelling the effect of the first phase conjugation process and provide said first beam in response thereto. 2748

247 PEN-TYPE INJECTOR HAVING AN ELECTRONIC CONTROL UNIT מזרק מסוג עט עם יחידת בקרה אלקטרונית [31] [87] [32] Int. Cl.8 A61M 005/24 DCA DESIGN INTERNATIONAL LIMITED, UNITED KINGDOM WO/2002/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] GB סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] An injection device having a drive mechanism (42) to expel selectively a dose of medicament from a medicament cartridge (40) through a needle unit (22), an electronic control unit to control the drive mechanism, and a dispense button (18) to generate a dispense button signal to the electronic control unit indicative of the dose to be expelled in which an arm button (16) causes a first arm button signal to be sent to the electronic control unit to permit the dose to be expelled, wherein the arm button is linked to a cover detection switch (28) such that the arm button will only function to arm an injector (2) when a cover (6) is not present. 2749

248 2750

249 [31] [87] ELECTRONIC COMPASS AND COMPENSATION OF LARGE MAGNETIC ERRORS FOR OPERATION OVER ALL ORIENTATIONS [32] Int. Cl.8 G01N 021/00 HONEYWELL INTERNATIONAL INC., U.S.A. WO/2002/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV מצפן אלקטרוני ופיצוי על שגיאות מגנטיות גסות לשם תפעול בכל הכיוונים [33] US ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A method of compensating an electronic compass to obtain accurate azimuth data for any orientation of the electronic compass despite the presence of perturbing magnetic effects, the method comprising: obtaining a measured magnetic field vector H MEAS representing magnetic field strength along three axes and a measured gravity vector G MEAS representing gravitational field strength along the same three axes; using a matrix compensation coefficient L E and a vector compensation coefficient H PE to correct measured magnetic field data by applying a formula of the form H EARTH= L E. H MEAS -H PE, where H EARTH is the compensated value for the Earth's true magnetic field; and calculating the azimuth data as a function of the corrected magnetic field data METHOD FOR STORING ENCRYPTED DATA שיטה לאיחסון נתונים מוצפנים [31] [87] /0061 [32] [33] CH Int. Cl.8 G06F 012/14, H04L 009/08, H04N 007/16, 007/167 NAGRACARD S.A., SWITZERLAND WO/2002/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים 2751

250 [57] A storing method of data extracted from an encrypted data stream sent to a decoder (STB) connected to a security module (SM) and connected to a storing unit (DB), this method consisting in reencrypting, without previous decryption, in the decoder the encrypted data sent to the decoder before they are transferred to the storing unit by at least one specific key (K1, K2). 2752

251 BACKGROUND LIGHT INTENSITY ADAPTIVE ILLUMINATING LIGHT SYSTEM מקור תאורה עם אפשרות שליטה על העוצמה לפי תנאי הרקע [72] Int. Cl.8 F21V 007/00, F41G 001/34, G02B 023/10 MEPROLIGHT (1990) LTD. מפרולייט (1990) בע"מ GABRIEL NECHUSHTAN גבריאל נחושתן SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, REHOVOT שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A reflex sight comprising: an optical combiner operative to permit a scene to be viewed therethrough and to reflect light to a viewer; a light source arranged with respect to said optical combiner such that light from said source is reflected to said viewer as an aiming dot, said light source comprising an ambient light collector; and an attenuating compensator, compensating for variations in intensity of ambient light thereby to cause said aiming dot to have a generally uniform size. 2753

252 PHARMACEUTICAL COMPOSITIONS WITH ANTIBIOTIC ACTIVITY CONTAINING FOSFOMYCIN TROMETHAMOL AND A STABILIZER תכשירי רוקחות בעלי פעילות אנטיביוטית המכילים פוספומיצין טרומתאמול ומייצב [31] MI20020A [32] [33] IT Int. Cl.8 A61K 009/16, 031/665, 033/00, A61P 031/00, C07F 009/00, 009/38 ZAMBON GROUP S.P.A., ITALY REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., רחוב אחד העם, 21 ת.ד. 4060, תל P.O.B. 4060, אביב TEL AVIV [57] A substance selected from: tribasic sodium or potassium citrate, monoacidic sodium or potassium citrate, tribasic sodium or potassium phosphate, monoacidic sodium or potassium phosphate, sodium or potassium carbonate, sodium or potassium bicarbonate, sodium or potassium tartrate, arginine, lysine or mixtures thereof, for use to stabilize Fosfomycin Tromethamol (FT) ANTIBODIES TO INSULIN-LIKE GROWTH FACTOR I RECEPTOR נוגדנים לקולט גורם גידול דימוי אינסולין I [31] [87] / [32] [33] US Int. Cl.8 A61K 039/395, 048/00, A61P 035/00, C07K 016/28, C12N 015/13, C12P 021/08 PFIZER INC., U.S.A. AMGEN FREMONT INC., U.S.A. WO/2002/ WOLFF, BREGMAN AND GOLLER, וולף, ברגמן וגולר, P.O.B. 1352, JERUSALEM 91013, ת.ד. 1352, ירושלים [57] A human monoclonal antibody or antigen-binding portion thereof that specifically binds to insulin-like growth factor I receptor (IGF-IR), wherein said antibody or portion binds to IGF-IR with a K d of 8 x 10-9 M or less. 2754

253 METHOD AND SYSTEM FOR FORWARD LINK BEAM FORMING IN WIRELESS COMMUNICATIONS שיטה ומערכת עבור יצירת קרן חוליה קדמית בתקשורת אל חוטית [31] [87] / [32] Int. Cl.8 H04B 007/06, H04M 001/00 QUALCOMM INCORPORATED, U.S.A. WO/2002/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A system (200) for forward link beam forming in a wireless communication system, comprising: an antenna configured to generate a plurality of antenna beam patterns (206), each of the antenna beam patterns having a corresponding signal transmission energy and being directed to a plurality of users of the wireless communication system; a control signal monitoring module (202) configured to receive a power control signal from a specific user among the plurality of users and to output a sequence of monitored signals; a signal statistic computation module (204) configured to determine a statistic for the specific user, said statistic comprising an average of the sequence of monitored signals from the control signal monitoring module over a specified time interval; an antenna beam pattern optimizing module (208) configured to narrow one of the antenna beam patterns based solely on the statistic of the specific user and focusing the signal transmission energy of said one antenna beam pattern on the specific user to obtain an optimizied antenna beam pattern for the specific user; and a base station using the optimized antenna beam pattern to transmit communication signals to the specific user. 2755

254 DOCUMENT AND METHOD FOR PERFORMING AN OPTICALLY- BASED DOCUMENT AUTHENTICATION מסמך ושיטה מבוססת אופטיקה לאימות מסמכים [31] [62] / [32] Int. Cl.8 G06K 009/74 DIVISION FROM BROWN UNIVERSITY RESEARCH FOUNDATION, U.S.A. EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] US איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] A method for authenticating a document, comprising the steps of: providing a document to be authenticated; illuminating at least a portion of the document with laser light that exceeds a threshold fluence; detecting a narrow band substantially non-saturable amplified spontaneous emission of at least one wavelength from the document in response to the step of illuminating; and declaring the document to be authentic only if the emission is detected. The parent application from which this application has been divided has not yet been published בקשת הורה לבקשה זו שטרם פורסמה 2756

255 ISOXAZOLINE DERIVATIVE AND HERBICIDE CONTAINING THE SAME AS THE ACTIVE INGREDIENT נגזרת איסוקסאזולין וקוטל עשבים המכיל אותה כהרכב פעיל [31] [87] [32] [33] JP Int. Cl.8 A01N 043/80, C07D 261/00, 413/12, 417/12, 498/04, 513/04 IHARA CHEMICAL INDUSTRY CO., LTD., JAPAN KUMIAI CHEMICAL INDUSTRY CO., LTD., JAPAN WO/2002/ SELIGSOHN GABRIELI & CO., זליגסון גבריאלי ושות', 31 YAVNE ST., P.O.B. 1426, רח' יבנה, 31 ת.ד. 1426, תל אביב TEL AVIV [57] An isoxazoline derivative or a pharmaceutically acceptable salt thereof of the formula: wherein R 1 and R 2 may be the same or different and are each a hydrogen atom, a C1 to C10 alkyl group, a C3 to C8 cycloalkyl group or a C3 to C8 cycloalkyl C1 to C3 alkyl group; or R 1 and R 2 may be bonded to each other to form a C3 to C7 spiro ring together with the carbon atoms to which they bond, R 3 and R 4 may be the same or different and are each a hydrogen atom, a C1 to C10 alkyl group or a C3 to C8 cycloalkyl group; or R 3 and R 4 may be bonded to each other to form a C3 to C7 spiro ring together with the carbon atoms to which they bond; or R 1, R 2, R 3 and R 4 may form a 5- to 8- membered ring together with the carbon atoms to which they bond; R 5 and R 6 may be the same or different and are each a hydrogen atom or a C1 to C10 alkyl group; Y is a 5- to 6- membered aromatic heterocylic group or condensed aromatic heterocyclic group having one or more hetero atoms selected from a nitrogen atom, an oxygen atom and a sulfur atom; the heterocyclic group may be substituted with 0 to 6 same or different groups as defined in the specification. 2757

256 HETEROCARPINE, A PLANT PROTEIN BINDING HUMAN GHRH הטרוקרפין, חלבון צמחי הקושר GHRH של אדם [31] [87] /02631 [32] [33] FR Int. Cl.8 A61K 038/16, A61P 005/04, 009/10, 035/00, C07K 001/14, 014/415, 016/16 SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.), FRANCE WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Isolated protein which can be obtained by extraction from the plant Pilocarpus heterophyllus, which is characterized in that it has a molecular mass of approximately 90.9 kda and comprises fragments of peptide sequences SEQ.ID.NO. 1, SEQ.ID NO.2 and SEQ.ID NO.3; said protein being able to be presented in a glycosylated or non-glycosylated form. [31] [87] IMPLANTS, DEVICE AND METHOD FOR JOINING TISSUE PARTS /01 [32] Int. Cl.8 A61B 017/68 WOODWELDING AG, SWITZERLAND WO/2002/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV שתלים, התקן ושיטה לחיבור חלקי רקמה [33] CH ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] Implant for creating a positivefit connection to a tissue part for connecting the tissue part with a further tissue part or with an artificial element replacing or supporting a further tissue part or being a 2758

257 therapeutic auxiliary device, wherein the implant at least partly consists of a material which is liquefiable by mechanical energy, wherein the liquefiable material is arranged on the implant in a manner such that is can be brought into contact with the tissue part and can be excited by mechanical oscillation and simultaneously be pressed against the tissue part for liquefying at least part of the liquefiable material and for pressing it into openings of the tissue part. N - SUBSTITUTED NONARYL- HETEROCYCLIC ARYLS AND THEIR USE FOR PREPARING MEDICAMENTS FOR TREATING PAIN ארילים הטרוציקלים N מותמרים שאינם ארילים והשימוש בהם להכנת תרופות לטיפול בכאב [31] [87] / [32] [33] US Int. Cl.8 A61K 031/395, A61P 025/00, 043/00, C07D 401/00, 401/12, 401/14, 403/12, 403/14, 409/14, 413/12, 413/14, 417/12, 417/14, 471/02, 473/02, 475/02, 487/02, C07F 007/18 MERCK & CO., INC., U.S.A. WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A compound of the formula: 2759

258 or pharmaceutically acceptable salts thereof, wherein NonAr is a nonaromatic 6 membered ring containing 1 nitrogen ring atom; HetAr is a 6 membered heteroaromatic ring containing 2 nitrogen ring atoms; HetAr is optionally substituted with 1 or 2 substituents, each substituent independently is C 1-4 alkyl, C 1-4 alkoxy, C 2-4 alkynyl, trifluoromethyl, hydroxy, hydroxy C 1-4 alkyl, fluoro, chloro, bromo, iodo, cyano, methylsulfanyl, cyclopropylethynyl-, phenylethynyl-, heteroarylethynyl-, - N(C 0-4 alkyl) (C 0-4 alkyl), nitro, (C 1-2 alkyl) (C 1-2 alkyl) NHC 2 -, (C 1-2 alkyl) NHCH 2 -, Si(CH 3 ) 3 -C-, or NH 2 C(O)-; A is C 1-4 alkylene-; B is aryl (CH 2 ) 0-3 O-C(O)-, heteroaryl (CH 2 ) 1-3 -O-C(O)-, indanyl (CH 2 ) 0-3 -O-C(O)-, aryl (CH 2 ) 1-3 C(O)-, aryl-cyclopropyl-c(o_)-, heteroaryl-cyclopropyl-c(o)-, heteroaryl (CH 2 ) 1-3 C(O)-, heteroaryl (CH 2 ) 1-3 -, aryl (CH 2 ) 1-3 NH-C(O)-, aryl (CH 2 ) 1-3 NH-C(NCN)-, aryl (CH 2 ) 1-3 -SO 2 -, heteroaryl (CH 2 ) SO 2 -, wherein any of the aryl or heteroaryl is optionally substituted by 1-5 substituents, each substituent independently is C 1-4 alkyl, C 3-6 cycloalkyl, C 1-4 alkoxy, trifluoromethyl, bromo, fluoro, or chloro; and X is H, OH, F, C 1-4 alkyl, C 1-4 alkoxy, NH 2, or X taken with an adjacent bond is =O. SINGLE SOURCE MIXTURES OF METAL SILOXIDES תערובות של סילוקסידים מתכתיים ממקור יחיד [31] [32] [33] US Int. Cl.8 C09D 001/00, C23C 016/40, H01L 021/316 AIR PRODUCTS AND CHEMICALS, INC., U.S.A. REINHOLD COHN AND ריינהולד כהן ושותפיו, PARTNERS, 21 AHAD HA'AM ST.,, 21 ת.ד. 4060, תל אביב רחוב אחד העם P.O.B. 4060, TEL AVIV [57] A metal siloxide precursor which is composed of a complex represented by the empirical formula: (R) m M (O SiR 1 R 2 R 3 ) n wherein M is a group 4 metal selected from the group consisting of zirconium and 2760

259 hafnium; R is (CH 3 CH 2 ) 2 N and R 1, R 2 and R 3 are ethyl; and m plus n is equal to a valence of the M metal (v). [31] [87] CIRCUIT ARRANGEMENT FOR A RESIDUAL-CURRENT CIRCUIT BREAKER A 909/2001 [32] Int. Cl.8 H02H 001/06 MOELLER GEBAUDEAUTOMATION GMBH, AUSTRIA WO/2002/ DR. YITZHAK HESS & PARTNERS, 279 HAYARKON ST., P.O.B. 6451, TEL AVIV סידור מעגל עבור מפסיק מעגל ע"י זרם נותר [33] AT ד"ר יצחק הס ושותפיו, רחוב הירקון, 279 ת.ד. 6451, תל אביב [57] A circuit arrangement for a residual-current breaker, comprising a detection apparatus (10) for a residual current in a supply network, which detection apparatus is preferably provided, in outgoing circuit with a conditioning circuit (20) for the residual current; an energy storage circuit (30) which is charged in accordance with the detected residual current; a trigger (40) which monitors the charged state of the energy storage circuit, and a contact unit (50) for generating a tripping voltage pulse for a tripping element for an isolator of at least one consumer that is fed by the supply network, with the trigger causing the contact unit to generate a tripping voltage pulse for the tripping element (60) once the energy storage circuit has attained a predetermined charged state (set charged state), where a second trigger (40') is provided, characterized in that the second trigger blocks the contact unit reaching a further predetermined charged state (minimum charged state) of the energy storage circuit. 2761

260 [31] [87] METHOD FOR IDENTIFICATION BY A HOST COMPUTER AVOIDING COLLISION OF ELEMENTS /00566 [32] Int. Cl.8 G06F 013/376, G06K 017/00 ASK S.A., FRANCE WO/2003/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] שיטה לזיהוי באמצעות מחשב אורח ומניעת התנגשות חלקיקים FR ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] An anti-collision process by a host computer of elements matching a given relationship with said host computer enabling the identification of said elements by the latter, each of said elements having an identification number between 0 and a maximum value (MAX); said process being characterized by the following steps: (a) transmission by said host computer of a query instruction capable of being received and recognized by any element matching said given relationship with said host computer, (b) when at least one of said elements matches said given relationship with said host computer, transmission by the latter of an anti-collision signal including an identification attempt digital value, (c) response by any element matching said given relationship with said host computer and having an identification number less than or equal (or greater than or equal) to said digital identification attempt value, and (d) detection of collision between several elements when said host computer receives several responses and in this case, transmission of an anti-collision instruction made up of an identification attempt digital value defined according to a given algorithm, or selection of the element by its identification number when there is only one response. 2762

261 DIHYDRO-BENZO [B] [1,4] DIAZEPIN-2-ONE DERIVATIVES AS MGLUR2 ANTAGONISTS II נגזרות של דיהידרו בנזו 4,1] [[b] דיאזפינ 2 ון כאנטגוניסטים II של MGLUR2 [31] [87] [32] [33] EP Int. Cl.8 A61K 031/5513, A61P 025/00, C07D 243/12, 401/04, 403/10, 403/14, 409/10, 413/10, 413/14, 417/10 F. HOFFMANN-LA ROCHE AG, SWITZERLAND WO/2002/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] Compounds of the formula 2763

262 wherein X is a single bond or an ethynediyl group; wherein in case X is a single bond, R 1 is cyano, halogen, C 1 -C 7 -alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 7 -alkoxy, fluoro-c 1 -C 7 -alkoxy, fluoro-c 1 -C 7 -alkyl, or is pyrrol-1-yl, which is unsubstituted or substituted by one to three substituents selected from the group consisting of fluoro, chloro, cyano, -(CH 2 ) 1-4 -hydroxy, fluoro- C 1 - C 7 -alkyl, C 1 -C 7 -alkyl, -(CH 2 ) n -C 1 -C 7 - alkoxy, -(CH 2 ) n -C(O)O-R", -(CH 2 ) 1-4 NR'R", hydroxy-c 1 -C 7 -alkoxy, and (CH 2 ) n -CONR'R", or is phenyl, which is unsubstituted or substituted by one or two substituents selected from the group consisting of halogen, C 1 -C 7 - alkyl, fluoro- C 1 -C 7 -alkyl, C 1 -C 7 - alkoxy, fluoro- C 1 -C 7 -alkoxy and cyano; in case X is an ethynediyl group, R 1 is phenyl, which is unsubstituted or substituted by one to three substituents selected from the group consisting of halogen, C 1 -C 7 -alkyl, fluoro-c 1 -C 7 - alkyl, C 3 -C 6 -cycloalkyl, C 1 -C 7 -alkoxy and fluoro- C 1 -C 7 -alkoxy; R 2 is NR'R", fluoro- C 1 -C 7 -alkoxy or 3-oxopiperazin-l-yl, pyrrolidin-l-yl or piperidin-l-yl, which rings are optionally substituted by R"; R' is hydrogen, C 1 -C 7 -alkyl, C 3 -C 6 - cycloalkyl, fluoro- C 1 -C 7 -alkyl or 2- C 1 -C 7 -alkoxy C 1 -C 7 -alkyl; R" is hydrogen, C 1 -C 7 -alkyl, C 3 -C 6 - cycloalkyl, fluoro- C 1 -C 7 -alkyl, 2-C 1 - C 7 -alkoxy C 1 -C 7 -alkyl, -(CH 2 ) 2-4 -di- C 1 -C 7 -alkylamino, (CH 2 ) morpholinyl, -(CH 2 ) 2-4 -pyrrolidinyl, - (CH 2 ) 2-4 -piperidinyl or 3-hydroxy- C 1 - C 7 -alkyl; Y is CH= or =N-; R 3 is halogen, C 1 - C 7 -alkyl, fluoro- C 1 -C 7 -alkyl, C 1 -C 7 - alkoxy, cyano, -(CH 2 ) n -C(O)-OR", - (CH 2 ) n -C(O)-NR'R", or is an optionally substituted five-membered aromatic heterocycle, which may be substituted by halogen, fluoro- C 1 -C 7 - alkyl, fluoro- C 1 -C 7 -alkoxy, cyano, - (CH 2 ) n -NR'R", -(CH 2 ) n -C(O)-OR", - (CH 2 ) n -C(O)-NR'R", -(CH 2 ) n -SO 2 - NR'R, -(CH 2 ) n -C(NH 2 )=NR", hydroxy, C 1 -C 7 -alkoxy, C 1 -C 7 - alkylthio, or by C 1 -C 7 -alkyl, which is optionally substituted by fluoro, hydroxy, C 1 -C 7 -alkoxy, cyano or carbamoyloxy; n is 0, 1, 2, 3 or 4; and their pharmaceutically acceptable addition salts. 2764

263 LIQUID FORMULATIONS FOR DERMAL APPLICATION TO CONTROL PARASITIC INSECTS IN ANIMALS תכשירים נוזליים לטיפול בעור המשמשים לטיפול נגד חרקים טפיליים בחיות [31] [87] [32] [33] DE Int. Cl.8 A01N 053/00, 053/06, C07D 213/00, 277/20 BAYER HEALTHCARE AG, GERMANY WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] Compositions, comprising (a) 35 60% by weight of the active compound permethrin (b) % by weight of imidacloprid or an imidacloprid analogue of the formula: in which R represents hydrogen, optionally substituted radicals of the group consisting of acyl, alkyl, aryl, aralkyl, heteroaryl and heteroarylalkyl; A represents a monofunctional group from the group consisting of hydrogen, acyl, alkyl, aryl, or represents a bifunctional group which is attached to the radical Z; E represents an electron-withdrawing radical; X represents the radicals CH= or =N-, where the radical CH= may be attached to the radical Z instead of an H-atom; Z represents a monofunctional group from the group consisting of alkyl, -O- R, -S-R, or represents a bifunctional group which is attached to the radical A or the radical X, where the substituents of the optionally substituted radicals listed above are selected from the group consisting of: alkyl having 1 to carbon atoms, alkoxy having 1 to 4 carbon atoms, alkylthio having 1 to 4 carbon atoms, haloalkyl having 1 to 4 carbon atoms and 1 to 5 halogen atoms, where the halogen atoms are identical or different; hydroxyl;

264 halogen; cyano; nitro; amino; monoalkyl-and dialkylamino having 1 to 4 carbon atoms; carboxyl; carbalkoxy having 2 to 4 carbon atoms; sulfo (-SO 3 H); alkylsulphonyl having 1 to 4 carbon atoms; arlsulphonyl having 6 or 10 aryl carbon atoms and also heteroarylamino and heteroarylalkylamino; (c) % by weight of N- methylpyrrolidone (d) 0-5% by weight of water (e) 0-0/5% by weight of phenolic antioxidants and (f) 0-0/5% by weight of organic acids. REMOVABLE CRYPTOGRAPHIC IGNITION KEY SYSTEM AND METHOD מערכת ושיטה להסרת מפתח איתחול קריפטוגרפי [31] [32] [33] US Int. Cl.8 G06F 001/00, 002/ H04L 029/06 HARRIS CORPORATION, U.S.A. REINHOLD COHN AND ריינהולד כהן ושותפיו, PARTNERS, 21 AHAD HA'AM ST.,, 21 ת.ד. 4060, תל אביב רחוב אחד העם P.O.B. 4060, TEL AVIV [57] A system for conducting secure operations, said system comprising: a removable cryptographic ignition key device; a processor configured to receive said removable cryptographic ignition key device; a proximity detector configured to determine if a distance between said removable cryptographic ignition key device and said processor is within a predetermined distance, a manual disable portion configured to disable secure operations regardless if a distance between said removable cryptographic ignition key device and said processor is within said predetermined distance, and a timer configured to determine an amount of time that said distance between said removable cryptographic ignition key device and said processor exceeds said predetermined distance, wherein said system is configured to: enable secure operations subsequent to said processor receiving said removable cryptographic ignition key device; conduct secure operations while said removable cryptographic ignition key device is within said predetermined distance of said processor; and disable secure operations if said amount of time that said distance between said removable cryptographic ignition key device and said processor exceeds said predetermined distance, as determined by said timer, is greater than a predetermined amount of time. 2766

265 APPARATUS AND METHOD FOR CONCURRENT CONVERSION OF MULTIPLE AUDIO AND VIDEO FORMATS מערכת ושיטה להמרה בו זמנית של פורמטים קוליים וחזותיים מרובים [87] Int. Cl.8 H04N 005/00, 007/16, 007/173, 007/24 OPTIBASE אופטיבייס, הרצליה WO/2002/ PEARL COHEN ZEDEK LATZER, פרל כהן צדק לצר, 5 SHENKAR ST., מרכז גב- םי 1, רח' שנקר, 5 ת.ד , P.O.B , הרצליה HERZLIYA [57] A modular, storage-less, realtime scalable video/audio streaming and switching system comprising a media format matrix, said media format matrix comprising: (a) at least one star topology packet switching fabric module, for managing network streaming inside said media format matrix; (b) one or more controller modules connected with said at least one switching fabric module and with an external management unit, for configuring and controlling said media format matrix; and at least one of a group consisting of: (c) one or more encoding modules 2767 connected with said switching fabric module, for receiving uncompressed video or audio and converting it into a predefined compressed format; (d) one or more decoding modules connected with said switching fabric module, for receiving compressed video or audio and converting it into a predefined uncompressed format; (e) one or more compressed stream interface modules connected with said switching fabric module, for transmitting compressed data between said switching fabric module and an external media interface; (f) one or more transcoding modules connected with said switching fabric

266 module, for receiving compressed streams from said switching fabric module, transcoding them into different compressed formats and sending said different compressed stream back to said switching fabric module; (g) one or more NIC modules connected with said switching fabric module, for connecting between said media format matrix and one or more distribution networks; and (h) one or more pre-processing modules connected with said switching fabric module, for processing uncompressed streams METHOD AND DEVICE FOR IMPROVING THE EXTERNAL BALLISTICS OF AN ARTILLERY SHELL שיטה והתקן לשיפור הבליסטיות החיצונית של פגז ארטילרי [31] [72] [87] [32] Int. Cl.8 F42B 014/02 BAE SYSTEMS BOFORS AB, SWEDEN ULF HELLMAN WO/2002/ EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] SE איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] An artillery shell comprising: a driving band groove (4) at a rear of the shell; a driving band (6) disposed within the driving band groove; a driving band groove filler (5) disposed within the driving band groove and comprising a plurality of springback filler elements; and an outer ring disposed between the driving band and the driving band groove filler. 2768

267 [31] [87] PIEZOELECTRIC TRANSDUCER ASSEMBLIES AND METHODS FOR THEIR USE [32] Int. Cl.8 H01L 041/113 SENX TECHNOLOGY, U.S.A. WO/2002/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] התקני מתמרים פיאזואלקטרי ושיטות השימוש בהם US ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A piezoelectric transducer assembly (1) comprising: an insertable transducer retainer assembly (2) comprising a housing (3) having an outside surface (4), a front (5) and a back (6), said back (6) having centered therein, a hub (7), said centered hub having a centered opening (8) therethrough and said centered hub being integrally connected to said retainer assembly, said outside surface having a fastening means (12) thereon and a tapered front outside circumferential edge; said insertable transducer retainer assembly having a first circular opening (13) in the front, said first circular piezoelectric transducer 2769 disposed therein; said piezoelectric transducer having a bottom surface and a top surface, said piezoelectric transducer having electrical leads (31) connected to the bottom surface thereof; a second opening in the front, deeper than the first circular opening and having a lesser diameter than the diameter of the first circular opening; the centered opening in the centered hub continuing on through the transducer retainer assembly housing and opening into the second opening to provide a continuous channel through the transducer retainer assembly (11) that exits at the hub; a receiving transducer retainer assembly comprising a housing (27), said

268 receiving transducer retainer assembly housing having a front (28) and a back, the back having centered therein a hub (24) integrally mounted thereon, said receiving transducer retainer hub having a back (25) and a front and being lesser in diameter than the diameter of the receiving transducer retainer assembly housing, the front of said receiving transducer retainer assembly having located therein an opening (29), said receiving transducer retainer assembly opening having an interior surface and a bottom (19); the interior surface having disposed thereon, fastening means compatible with the fastening means of the insertable transducer retainer assembly, said opening having a tapered circumferential edge at the bottom; a saucer-like depression (30) below the bottom of the opening in the receiving transducer retainer assembly, said saucer-like depression having a bottom, the surface area of the top of the saucer-like depression being relative to the surface area of the top of the piezoelectric transducer, said surface area relationship having a ratio in the range of from zero to 1:1; a channeled opening from the bottom of the saucer-like depression through the center of the receiving transducer retainer hub, the interior of the receiving transducer retainer hub having an adapting means for adapting the receiving transducer retainer assembly to a pump, said pump being a gas pump TAMPER-EVIDENT ADHESIVE TAPE Int. Cl.8 B32B 007/12 BSECURE LTD. EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA סרט אריזה דביק לעדות פריצה ביסקיור בע"מ איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה 2770

269 [57] A tamper-indicating adhesive tape (10) comprising a first top layer (12) of transparent polymer film substrate having an upper (14) and a lower (16) side, provided with an adhesive-release coating (18) on said upper side; a second layer (20) being printed first indicia comprising a portion of the total indicia to be seen, printed on said lower side of said first layer; a third layer (24) being transparent and containing a release varnish, said third layer being applied onto said second layer, comprises at least 80% transparent ink and up to 20% of a silicone-based release varnish, a fourth layer (26) being a transparent UV cured or heat cured adhesive applied onto said third layer; a fifth layer (22) being second indicia comprising the remaining portion of the total indicia, printed on said fourth layer to locate with and complete graphics of said first indicia; and a sixth bottom layer (28) of a pressuresensitive rubber based hot melt adhesive applied onto said fifth layer; whereby attempted removal of said tape after application to a solid surface causes tape delamination between said third layer and either adjacent layer, with additional conspicuous damage done to layers 1-6. (PYRIDO/THIENO)-[F]- OXAZEPIN-5-ONE DERIVATIVES AS POSITIVE MODULATORS OF THE AMPA RECEPTORS תולדות פירדו/תיאנו [ f ] אוקסזפין 5 און מודולטורים של רצפטורים AMPA חיוביים [31] [87] [32] [33] EP Int. Cl.8 A61K 031/553, A61P 025/28, C07D 498/12 N.V. ORGANON, THE NETHERLANDS WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV

270 [57] A (pyrido/thieno)-[f]-oxazepin- 5-one derivative of the formula wherein R 1, R 2 and R 3 are independently H or (C 1-4 ) alkyl; Ar represents a fused thiophene or pyridine ring optionally substituted with one or more substituents selected from (C 1-4 ) alkyl, (C 1-4 ) alkyloxy, (C 1-4) alkyloxy (C 1-4 )-alkyl, CF 3, halogen, nitro, cyano, NR 4 R 5, NR 4 COR 6, and CONR 4 R 5 ; R 4 and R 5 are independently H or (C 1-4 )alkyl; or R 4 and R 5 form together with the nitrogen atom to which they are bound a 5- or 6- membered saturated heterocyclic ring, optionally containing a further heteroatom selected from O, S or NR 6 ; R 6 is (C 1-4 ) alkyl; A represents the residue of a 4-7 membered saturated heterocyclic ring, optionally containing an oxygen atom, the ring being optionally substituted with 1-3 substituents selected from (C 1-4 ) alkyl, (C 1-4 ) alkyloxy, hydroxy, halogen and oxo; or a pharmaceutically acceptable salt thereof; with the proviso that the compound of formula I wherein Ar is a [3,2-f] fused pyridine ring; each of R 1 -R 3 is H, and A represents (CH 2 ) 3 ; is excluded ELEMENTARY AND COMPLEX COUPLING DEVICES AND THEIR USE התקני הצמדה בסיסיים ומורכבים ושימושם [31] [32] Int. Cl.8 F16C 011/00 THALES NEDERLAND B.V., THE NETHERLANDS SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] NL סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] An elementary coupling device comprising: a means (1) for stiffening the elementary coupling device against torsion, two means (2', 2") for linking the means for stiffening to a second object (40) to be coupled, two first means (1/2', 1/2") for hinging each means for linking directly or indirectly on the second object to be coupled at two separate points, two second means (1/3', 1/3") for hinging the means for stiffening on each means for linking at two separate points, two third means (2/4', 2/4") hinging the means for stiffening directly or indirectly on a first object to be coupled at two separate points. 2772

271 [31] [72] METHOD AND DEVICE OF IMAGING WITH AN IMAGER HAVING A FIBER PLATE COVER / [32] Int. Cl.8 A61B 001/05, H01L 021/8238 GIVEN IMAGING LTD. GAVRIEL JOSEPH IDDAN PEARL COHEN ZEDEK LATZER, 5 SHENKAR ST., P.O.B , HERZLIYA שיטה ומכשיר להדמייה כאשר למכשיר יש כיסוי עשוי מסיבים [33] US גיוון אימג'ינג בע"מ, יקנעם גבריאל יוסף עידן פרל כהן צדק לצר, מרכז גב- םי 1, רח' שנקר, 5 ת.ד , הרצליה [57] An autonomous in vivo device comprising: an imager; and a fiber plate cover disposed on sensor elements to said imager, said fiber plate cover to transfer to said sensor elements an image of an object in contact with said fiber plate cover while said in vivo device passes through a body lumen, said fiber plate cover configured to be contiguous with an outer wall surrounding said in vivo device. 2773

272 MULTI-DETECTION OF HEARTBEAT TO REDUCE ERROR PROBABILITY איתור רב ערוצי של HB להורדת הסיכוי לטעות [31] [87] / [32] [33] US 60/ US US 60/ US US Int. Cl.8 H04B 001/707, 007/26, H04J 011/00, 013/00, H04L 027/26, H04Q 007/38 TANTIVY COMMUNICATIONS, INC., U.S.A. WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A method for use in a base station, the method comprising: booting a detection processor wherein the detection processor comprises a state machine and a hypothesis detector; receiving a signal from a wireless transmit/receive unit (WTRU) wherein the signal includes a maintenance channel, a plurality of traffic channels, an access channel, a heartbeat standby channel, and a heartbeat request active channel; processing the received signal and outputting a determined a heartbeat energy level and a request energy level to the hypothesis detector, wherein a heartbeat channel processor processes the heartbeat standby channel to determine the heartbeat energy level and a request channel processor processes the heartbeat request active channel to determine the request energy level; determining the signal type of the received signal in the hypothesis detector; processing the output of the hypothesis detector in the state machine and determining whether the received signal is a request to transmit data according to predetermined criteria; and allocating at least one traffic channel to the WTRU when the received signal is a request to transmit data. 2774

273 The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו. TRANSMITTAL OF HEARTBEAT SIGNAL AT A LOWER LEVEL THAN HEARTBEAT REQUEST העברה של אות HB בדרגה נמוכה יותר מאות HB מבקש [31] [87] / [32] [33] US US 60/ US US Int. Cl.8 H04B 007/005, 007/208, 007/216, 007/26, H04J 003/00, 011/00, 013/00, H04L 001/16, 007/06, 027/26, H04Q 007/00, 007/20, 007/36 TANTIVY COMMUNICATIONS, INC., U.S.A. WO/2002/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A code division multiple access (CDMA) user device comprising: a transceiver; and a controller configured to control the transceiver such that a connection with a base station is established, a signal is transmitted from the transceiver over a reverse link to indicate the presence of the CDMA user device to the base station, and at least one signal is transmitted from the transceiver to the base station over the reverse link to request that the base station reserve a reverse link traffic channel for the CDMA user device. 2775

274 The applications for division from this application have not yet been published, בקשות חלוקה מבקשה זו שטרם פורסמו ATMOSPHERIC OPTICAL DATA TRANSMISSION SYSTEM מערכת שידור נתונים אופטית אטמוספרית [31] [72] [87] [32] [33] US Int. Cl.8 G02B 026/06, H04B 010/10, 010/105, 010/22 AOPTIX TECHNOLOGIES, INC., U.S.A. ELON J. GRAVES, MALCOLM J. NORTHCOTT WO/2003/ JMB, FACTOR & CO. LTD., ג'יי אמ בי, פקטור אנד קו בע"מ, רחוב המרפא, הר חוצבים, ת.ד.,45087 PARK, HAR HOTZVIM HI-TECH P.O.B , ירושלים JERUSALEM [57] A free-space optical data determining characteristics of a transmission system, comprising: first wavefront of light transmitted from and second telescopes spaced from the second telescope across a second and aimed at each other, a light free-space optical path to the first transmitter operably coupled to the telescope and pre-correcting a first telescope for providing dataencoded wavefront of the data-encoded light in light to the first telescope response to said characteristics, which directs that data-encoded light wherein the second free-space optical across a first free-space optical path to path and the first free-space optical the second telescope, a light receiver path encounter substantially the same operably coupled to the second aberrations, and second adaptive telescope for receiving the dataencoded optics system provided with the light from the first telescope, second telescope for determining a first adaptive optics system provided characteristics of a wavefront of light with the first telescope for transmitted from the first telescope 2776

275 across the first free-space optical path to the second telescope across the first free-space optical path to the second telescope and correcting a wavefront of the data-encoded light in response to said characteristics [31] [87] DISPERSITY CODING FOR INVERSE MULTIPLEXING [32] Int. Cl.8 H04L 012/56 NONEND INVENTIONS N.V., THE NETHERLANDS WO/2003/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] NL קידוד מפוזר להיפוך ריבוב ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A method for digital inverse multiplexing digital data comprising: splitting a packet of digital data into: a first flow wherein the packet f digital data is sent from front to rear; a second flow wherein the packet of digital data is sent from rear to front; and a third flow, said third flow including a flow of data elements obtained from each time that a first data element from a rear part of a front sub-area of the packet of digital data and a second data element from a front part of a rear sub-area of the packet of digital data are reduced into a third data element by means of a reversible operation. 2777

276 [31] [87] INDIVIDUAL PLANT WATERING DEVICE /09450 [32] / / Int. Cl.8 A01G 027/00 AQUASOLO SYSTEMS, FRANCE WO/2003/ G.E. EHRLICH (1995) LTD., AYALON TOWER, 15 TH FLOOR, 11 MENACHEM BEGIN ST., RAMAT GAN מכשיר להשקיית צמח בודד [33] FR FR FR ג'י.אי.ארליך (1995) בע"מ, מגדל אילון, קומה 15,רחוב מנחם בגין 11, רמת גן [57] A fitting consisting of a piece of injected plastic material, permitting to interconnect a water reservoir and a hollow cone of porous ceramic material to provide a device allowing to individually dispense water to plants, especially potted plants, proximate of their roots, and in predetermined volume, comprising: an intermediate disk portion (4) having an aperture (5) at its center; a threadfree cylinder portion (A) arranged on one side of the intermediate disk portion and including one or two thread-free cylinders (7, 8) adapted to be permanently fixed to the cone; a threaded cylinder portion (B) arranged on the other side of the intermediate disk portion and including two threaded cylinders each having an internal threaded portion (13, 14); all in a coaxial relationship; the internal threaded portions of the two threaded cylinders being adapted to be threaded with a relatively large bottle and a relatively small bottle, respectively. 2778

277 [72] METHOD OF TERRAIN FOLLOWING Int. Cl.8 G05D 001/04 RAFAEL ADVANCED DEFENSE SYSTEMS LTD. NITZAN SHARAV-SHAPIRO, GADI ZILBERMAN DR. MARK FRIEDMAN LTD., MOSHE AVIV TOWER, 54 TH FLOOR, 7 JABOTINSKY ST., RAMAT GAN שיטה לביצוע טיסה עוקבת קרקע רפאל מערכות לחימה מתקדמות בע"מ, חיפה ניצן שרב-שפירו, גדי זילברמן ד"ר מרק פרידמן בע"מ, מגדל משה אביב, ק. 54, רח ז'בוטינסקי 7, רמת- גן [57] An air vehicle comprising: (a) a memory for storing a map; (b) a processor for: (i) partitioning a flight corridor among a set of at least one frame, and (ii) as the air vehicle enters each of said at least one frame: (A) based on said map, providing a respective terrain profile for a respective portion of said flight corridor that lies within said each frame, and (B) transforming said respective terrain profile into a respective terrainfollowing flight profile for said each frame in accordance with at least one performance parameter of the air vehicle; and (C) a propulsion and guidance system for flying the air vehicle within said flight corridor in accordance with said at least one respective flight profile. 2779

278 AQUEOUS DISPERSION COMPRISING STABLE NANOPARTICLES OF A WATER- INSOLUBLE ACTIVE SUBSTANCE AND AN EXCIPIENT LIKE A MIDDLE CHAIN TRIGLYCERIDE (MCT) תפזיר מימי הכולל נאנו חלקיקים יציבים של חומר פעיל בלתי מסיס במים וחומר בלתי וחומר דוגמת טריגליצרידים בעלי שרשרת בינונית (MCT) [31] [72] [87] [32] Int. Cl.8 A61K 009/00, 009/10, 009/16 ASTRAZENECA AB, SWEDEN PIA MARGARETHA CECILIA HEDBERG, TOMMY URBAN SKANTZE, LARS CHRISTIAN VON CORSWANT, ANNA ELIZABETH ZACKRISSON, PER LENNART LINDFORS, ULF OLSSON WO/2003/ S. HOROWITZ & CO., ZION HOUSE, ROTHSCHILD BLVD., TEL AVIV [33] GB GB 41-45, תל ש. הורוביץ ושות', בית ציון, שדרות רוטשילד אביב [57] A process for the preparation of a stable dispersion of solid particles in an aqueous medium comprising: combining (a) a first solution comprising a pharmacologically active substance having a solubility in water at 25 o C of less than 0.5 mg/ml, a water-miscible organic solvent and an inhibitor, with (b) an aqueous phase comprising water and optionally a stabilizer, thereby precipitating solid particles comprising the inhibitor and the pharmacologically active substance; and optionally removing the water-miscible organic solvent; wherein: (i) the inhibitor is a non-polymeric hydrophobic organic compound; (ii) the inhibitor is less soluble in water than the pharmacologically active substance; (iii) the inhibitor is not a phospholipid and (iv) the inhibitor is sufficiently miscible with the pharmacologically active substance to form solid particles in the dispersion comprising a substantially single phase mixture of the substance and the inhibitor. 2780

279 [72] DOUBLE-SIDED CUTTING INSERT AND MILLING CUTTER Int. Cl.8 B23C 005/16, 005/22 ISCAR LTD. CAROL SMILOVICI, ASSAF BALLAS ISCAR LTD., P.O.B. 11, TEFEN שימה דו צדדית וכרסום ישקר בע"מ, תפן קרול שמילוביץ', אסף בלס ישקר בע"מ,, ת.ד. 11, תפן [57] A double-sided cutting insert (10), for use in a milling cutter, comprising: two identical opposing end surfaces (12) and a peripheral side surface (14) extending therebetween, the peripheral side surface comprising two opposing identical major side surfaces (18); four spaced apart major cutting edges (34), each major cutting edge formed at the intersection of each major side surface with each end surface; and a primary relief surface adjacent each major cutting edge, wherein: in each cross section of the cutting insert taken in a plane generally perpendicular to the major side surfaces, a line tangent to the primary relief surface (50) extending from the major cutting edge adjacent each primary relief surface is inclined to a median plane (M) of the cutting insert at an acute interior angle; and each end surface has four corners, two diagonally opposed lowered corners (30) and two diagonally opposed raised corners (28), the lowered corners being closer to the median plane than the raised corners. 2781

280 [87] CONCATENATABLE POINT-TO- MULTIPOINT (PTMP) BROADCAST MESSAGES FOR DISPLAYING DISPLAY MESSAGES ON PERSONAL CELLULAR TELECOMMUNICATION DEVICES Int. Cl.8 H04L 012/18, H04Q 007/22 CELLTICK TECHNOLOGIES LTD. WO/2003/ SIMON KAY, PATENT ATTORNEY, P.O.B , NETANYA הודעות שידור מנקודה אחת למספר נקודות (PTMP) הניתנות לשירשור לשם הצגת הודעות על מכשירי תקשורת סלולריים אישיים סלטיק טכנולוגיות בע"מ, הרצליה סיימון קיי, עו"פ,, ת.ד , נתניה [57] For use in a mobile cellular telecommunications network for displaying a display message on a personal cellular telecommunications device, the display message being transportable over an air interface by P 1 Point-To-MultiPoint (PTMP) broadcast messages each comprising (a) a header including (i) a macromessage identifier for identifying a macromessage; (ii) a macromessage page field for specifying a total number of pages I in a macromessage where K I 1 and K is a predetermined maximum number of PTMP broadcast messages in a macromessage; and (iii) a macromessage page counter for specifying a page number J=(1, 2,, I-1, I K) of a PTMP broadcast message in a macromessage, and (b) a payload including a reserved pseudoheader and a payload remainder for storing actual content, the pseudoheader having (i) a display message identifier for identifying a display message; and (ii) a PTMP broadcast message counter Q=(1, 2, P-1, P) for specifying the location of a PTMP broadcast message in a sequence of P PTMP broadcast messages. 2782

281 DEVICE FOR MEASURING ABERRATIONS IN AN EYE-TYPE SYSTEM מכשיר למדידת סטיות במערכת דמויית עין [31] [87] /11112 [32] Int. Cl.8 A61B 003/103 IMAGINE EYES, FRANCE WO/2003/ EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] FR איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] A device for measuring the aberrations in an eye-type system, comprising: an illumination path (VE) with notably means (SRC) for transmitting an illumination beam (FE) to form by backscattering on the retina of the eye a secondary light source; and a test path (VA) with notably test means (MA) in a given test plane (PA) of the phase of the wave emitted by said secondary 2783 source and emerging from the eye, characterised in that it comprises moreover; imaging means (L1) and eye-positioning means enabling in particular to position a predetermined plane of the eye in a focal plane of said imaging means, a stray reflection filtering element (FLT) where of the centre defines with the optical centre of the imaging means a measurement axis (z), substantially centred on the

282 pupil of the eye, optical separation means (LM1) placed on the measurement axis and defining the illumination path and the test path, on the illumination path, an illumination diaphragm (APT), of predetermined aperture, optical conjugation means (L2, L3) centred on the measurement axis and enabling optical conjugation between said predetermined plane of the eye, the plane of the illumination diaphragm and the test plane, and characterised in that the illumination beam converges substantially at the centre of the filtering element, in that the filtering element, the illumination path, the test path, the separation means and the conjugation means are interdependent, placed on a platform (PTF1) mobile relative to the imaging means along the optical axis of said means (z), enabling adjustment, with respect to the ametropia of the eye, of the optical conjugation by said means of the retina of the eye with the centre of the filtering element, and in that the illumination diaphragm is off-centre with respect to the measurement axis, so that the stray light flux reflected by the cornea of the eye, the imaging means as well as any diopter situated between the filtering element and the cornea, is deflected from the test path by the filtering element. [31] [87] FLEXIBLE THIN BATTERY AND METHOD OF MANUFACTURING SAME [32] Int. Cl.8 H01M 002/02, 010/40 EVEREADY BATTERY COMPANY, INC., U.S.A. WO/2003/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] סוללה דקה וגמישה והשיטה לייצורה US ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב 2784

283 [57] A battery (1) comprising an anode electrode (3), a cathode electrode (5), electrolyte, at least one external electrode contact and a battery enclosure sealed about at least a portion of the perimeter (17) of the battery, said battery enclosure comprising electrically conductive material, said external electrode contact formed from said electrically conductive material, wherein the battery enclosure comprises a laminate comprising first, second and third layers, wherein the third layer comprises the electrically conductive material and is sandwiched between the first and second layers. ORAL DOSAGE COMPOSITION OF PROPIVERINE OR A PHARMACEUTICALLY ACCEPTABLE SALT THEREOF PROVIDING PROLONGED RELEASE OF THE ACTIVE INGREDIENT תכשיר למתן פומי של פרופיוארין או מלח שלו המקובל ברוקחות עם שחרור מושהה של המרכיב הפעיל [31] [87] [32] [33] DE Int. Cl.8 A61K 009/00, 009/14, 009/20, 009/22, 009/28, 009/48, 009/52 APOGEPHA ARZNEIMITTEL GMBH, GERMANY WO/2003/ DR. YITZHAK HESS & PARTNERS, ד"ר יצחק הס ושותפיו, 279 HAYARKON ST., P.O.B. 6451, רחוב הירקון, 279 ת.ד. 6451, תל אביב TEL AVIV [57] A pharmaceutical composition for oral administration having prolonged release of the active agent, comprising propiverine and/or one or several pharmaceutically acceptable salts thereof in an amount of 4 mg to 60 mg of propiverine or the corresponding equivalent amount of a 2785 propiverine salts or a mixture thereof, being coated with one or more controlled releasing layers, said layer(s) comprising a retarding material insoluble in gastric fluid and insoluble in intestinal fluid and/or a retarding material insoluble in gastric fluid and soluble in intestinal fluid,

284 and/or being embedded in a controlled release matrix, which includes a swellable or insoluble material, wherein the composition has the following in vitro release, measured in 750 ml of 0.1 N hydrochloric acid during the first hour and subsequently measured in 750 ml USP buffer at ph = 5.8 using a Ph. Eur. Basket method at 100 rpm and 37 o C; 0-20% propiverine, released after 1 hour, 10-45% propiverine, released after 3 hours, 30-60% propiverine, released after 5 hours, 40-75% propiverine, releaed after 7 hours, 50-80% propiverine, released after 9 hours, 60-90% propiverine, released after 12 hours. [31] [87] FUNGICIDAL COMPOSITION BASED ON AT LEAST ONE PYRIDYLMETHYLBENZAMIDE DERIVATIVE AND AT LEAST ONE DITHIOCARBAMATE DERIVATIVE /13688 [32] Int. Cl.8 A01N 043/40, C07D 213/24 BAYER CROPSCIENCE S.A., FRANCE WO/2003/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA הרכב קוטל פטריות מבוסס על נגזרת אחת לפחות של פירידילמתילבנזנאמיד ועל נגזרת אחת לפחות של דיתיאוקרבמאנט [33] FR לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] Fungicidal compositions comprising: (a) a pyridylmethylbenzamide derivative of the formula in which R 1 is chosen from a hydrogen atom, an optionally substituted alkyl radical and an optionally substituted acyl radical; R 2 is chosen from a hydrogen atom and an optionally substituted alkyl 2786

285 radical; R 3 and R 4, which are identical or different are independently chosen from a halogen atom, the hydroxyl radical, the cyano radical, the nitro radical, the radical SF 5, the trialkylsilyl radical, an optionally substituted amino radical, an acyl radical, and a group E, OE or SE, in which E is chosen from an alkyl, alkenyl, alkynyl, cycloalkyl, cycloalkenyl, aryl and heterocyclyl radical, it being possible for each of them to be optionally substituted; c represents 0, 1, 2, 3 or 4; q represents 0, 1, 2, 3 or 4; and their agriculturally acceptable possible optical and/or geometric isomers, tautomers and addition salts with an acid or a base; and (b) a compound (II) chosen from dithiocarbamates, and their agriculturally acceptable isomers and addition salts with an acid; the compound (I)/compound (II) ratio ranging from 1/500 to 30/1. USE OF THYMULIN-LIKE PEPTIDES FOR MAKING PAIN- RELIEVING MEDICINES שימוש בפפטידים דמוי תימולין להכנת תרופות לשיכוך כאב [31] [87] /12984 [32] [33] FR Int. Cl.8 A61K 038/08, 038/22, A61P 025/02, 025/06, 029/00, C07K 007/06, 014/575 INSTITUT NATIONAL DE LA SANTE ET DE LA RECHERCHE MEDICALE (INSERM), FRANCE CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE (C.N.R.S), FRANCE NAYEF SAADE, LEBANON BARED SAFIEH-GARABEDIAN, LEBANON WO/2003/ REINHOLD COHN AND ריינהולד כהן ושותפיו, PARTNERS, 21 AHAD HA'AM ST.,, 21 ת.ד. 4060, תל אביב רחוב אחד העם P.O.B. 4060, TEL AVIV [57] Use of peptide analogues of thymulin, except thymulin, that are inactive relative to the immune system, and having anti-pain activity, for manufacturing a medicine for the treatment of pain. 2787

286 METHOD AND SYSTEM FOR SELECTING A BEST SERVING SECTOR IN A CDMA DATA COMMUNICATION SYSTEM שיטה ומערכת לבחירת סקטור המשרת באופן הטוב ביותר במערכת תקשורת נתונים CDMA [31] [87] / [32] [33] US Int. Cl.8 H04B 007/04, 007/26, H04J 013/00, H04L 012/56, H04Q 007/38 QUALCOMM INCORPORATED, U.S.A. WO/2003/ SANFORD T.COLB & CO., סנפורד ט. קולב ושות', P.O.B. 2273, שער הגיא 4, מרמורק, ת.ד. 2273, REHOVOT רחובות [57] A method for selecting a best serving sector in a CDMA communication system, said method comprising steps of: comparing a plurality of signal levels received from a plurality of active sectors with a signal level of a current serving sector to produce a difference; generating a delta credit for each of said plurality of active sectors based on said difference; accumulating a plurality of delta credits to produce an accumulated total credit; identifying said best serving sector from said accumulated total credit. 2788

287 [31] MULTIPLE WEAPON SYSTEM FOR AN ARMORED VEHICLE [32] Int. Cl.8 F41A 023/34 ELBIT SYSTEMS LTD. BOROCHOV, KORAKH, ELIEZRI & CO., 15TH FLOOR, ATIDIM TOWER, KIRYAT ATIDIM, P.O.B , TEL AVIV עמדת ירי מרובת נשקים לרכב משוריין [33] IL אלביט מערכות בע"מ, חיפה בורוכוב קורח אליעזרי ושות', מגדל כלל עתידים, ת.ד , תל- אביב [57] Land vehicle weapon system (100) comprising: a base mount (120) coupled with a land vehicle (102); a weapon mount; a plurality of different weapons (108) coupled with said weapon mount; a weapon moving mechanism coupled between said base mount and said weapon mount, said weapon moving mechanism being operable to move said different weapons to a combined configuration, between a transportation configuration and a static firing configuration; a plurality of moving actuator elements coupled with at least one of said base mount, said weapon mount, said different weapons, and with said weapon moving mechanism; a sensing mechanism coupled with a least one of said weapon mount, said different weapons and with said base mount; and at least one user interface coupled with said different weapons, said weapon moving mechanism, said moving elements, and with said sensing mechanism, said at least one user interface enabling a user to remotely operate said different weapons; wherein said weapon moving mechanism is in the form of a four bar linkage whose first link is fixed and is the same as said base mount, a second link of said four bar linkage being rotatably coupled with said first link, a third link of said four bar linkage being rotatably coupled with said second link and with a fourth link of said four bar linkage, said fourth link being rotatably coupled with said first link, at least one of said second link and said fourth link being slidably coupled with said first link, said weapon mount being coupled with at least one of said third link and said fourth link, said weapon moving mechanism being in said transportation configuration, when said second link, said third link, and said fourth link are substantially aligned along a substantially horizontal flat plane, said weapon moving mechanism being in said static firing configuration, when said four bar linkage is in a substantially triangular geometric form. 2789

288 [31] METHOD OF REPLACING AN ABRADABLE PORTION ON THE CASING OF A TURBOJET FAN /04906 [32] [33] Int. Cl.8 B23P 006/00, F01D 011/12, 025/28 SNECMA SERVICES, FRANCE EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA FR שיטה להחלפת רכיב בר שחיקה במעטפת של מניפת טורבו סילון איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] A method of replacing an characterized in that it comprises the abradable portion on the casing of a following operations: turbojet fan, the turbojet having a (a) removing the worn abradable rotary portion, this rotary portion itself portion; comprising a shaft having a fan stage (b) preparaing a new abradable attached to its front end, the fan stage portion; itself comprising a hub supporting a (c) applying adhesive to the bonding plurality of blades, the turbojet also surfaces of the abradable portion and comprising an annular fan casing (60) of the fan casing said bonding surfaces surrounding the fan stage, said fan having previously been cleaned; casing comprising an inside wall (70) (d) applying the abradable portion against which a likewise annular against the inside wall of the fan abradable portion (80) is bonded, the casing; bonding surfaces (82, 86) of the (e) putting an "inside" heating belt abradable portion and of the fan (100) into place against the sealing casing, the surface of the abradable surface of the abradable portion, the portion opposite from its bonding inside heating belt completely surface being referred to as its covering the abradable portion; "sealing" surface, the fan casing (f) putting holding sectors (110) into having a plurality of fixing points place against the inside heating belt (96), the fan stage having previously each holding sector including an been removed, the method being inflatable bladder (120), the abradable 2790

289 portion and the inside heating belt being sandwiched in full between the fan casing and the bladders, the holding sectors themselves being held in place by a plurality of straps (125) attached to the fan casing by the fixing points; (g) connecting the bladders to a common source (130) of air under pressure and connecting the inside heating belt to a regulated electrical power supply (140), pressurizing the bladders, and heating the adhesive in application of a cycle of temperature and pressure conditions that is adapted to the adhesive used and to the thermal conductivity of the fan casing; and (h) cooling and removing the holding sectors and the inside heating belt [31] SUB-CALIBRE PENETRATOR PROJECTILE /05659 [32] Int. Cl.8 F42B 014/06 GIAT INDUSTRIES, FRANCE REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] FR טיל תת קליבר חודר ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A sub-calibre penetrator projectile (1) incorporating a penetrator (2) and a sabot (3) formed of several segments, the penetrator and sabot incorporating profiles (D2, D3) that cooperate with one another so as to ensure the axial drive of the 2791 penetrator by the sabot when the projectile is being fired, such projectile wherein there is axial play (J) between the profile on the sabot and that on the penetrator so as to enable a limited relative axial displacement of the sabot with respect

290 to the penetrator, means being provided to ensure the radial locking of the sabot segments by the penetrator in the foremost position of the sabot with respect to the penetrator, this locking no longer being ensured in the rearmost position of the sabot with respect to the penetrator. [31] [87] PROJECTILE HAVING A HIGH PENETRATING ACTION AND LATERAL ACTION AND EQ U IP P ED WITH A N INTEGRATED FRACTURING DEVICE [32] Int. Cl.8 F42B 012/20 RHEINMETALL WAFFE MUNITION GMBH, GERMANY WO/2003/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA טיל בעל פעילות חדירה גבוהה ופעילות רוחבית המצויד במתקן שבירה משולב [33] EP לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] An active effective body (1), generating means (5) comprising one comprising: an effective body casing or more pressure-generating elements (2); a pyrotechnical pressure- (6); and an activatable initiating 2792

291 device (7) for initiating said pressuregenerating means, characterised by an inert pressure-transmitting medium (4) disposed within said effective body casing, as a separate component with respect to said pressure-generating means of said effective body, to which said pressure-generating means is adjacent or into which said pressuregenerating means is inserted, wherein the ratio of the pyrotechnical mass of said pressure-generating means to the mass of said inert pressuretransmitting medium is 0.5, and said pressure-transmitting medium is entirely or partially constituted of a material selected from the group comprising light metals or their alloys, plastically deformable metals or their alloys, duroplastic or thermoplastic synthetic materials, organic substances, liquid media, elastomeric materials, glass-like or pulverous materials, pressed members of glasslike or pulverous materials, and mixtures or combinations thereof. GPS EQUIPPED CELLULAR PHONE USING A SPDT MEMS SWITCH AND SINGLE SHARED ANTENNA טלפון סלולרי המצויד ב GPS המשתמש בממסר MEMS SPDT ומשושה יחידה משותפת [31] [87] / [32] Int. Cl.8 H01Q 021/28, H04B 001/38 QUALCOMM INCORPORATED, U.S.A. WO/2003/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] An antenna sharing system (10) for use with an antenna (12) comprising: a first matching network (16) coupled to a first circuit (20); a 2793 second matching network (18) coupled to a second circuit (22); and a switch (14) having a first throw coupled to said first network, a second

292 throw coupled to said second network, and a pole coupled to said antenna. BILAYER HDP CVD/PE CVD CAP IN ADVANCED BEOL INTERCONNECT STRUCTURE AND METHOD THEREOF מכסה דו שכבתי לציפוי כימי של אדים לפלסמה רבת הבלטה/פלסמה מוגברת במבניחיבור מתקדמים בקדם ייצור ושיטה לנ"ל [31] [87] / [32] Int. Cl.8 H01L 021/44 IBM CORPORATION, U.S.A. WO/2003/ IBM LABORATORIES, HAIFA UNIVERSITY, HAIFA [33] US מעבדות יבמ מחלקת קנין רוחני, אוניברסיטת חיפה הר הכרמל, חיפה [57] A method for forming an interconnect structure on a substrate, the method comprising the steps of: depositing a dielectric material on the substrate, thereby forming a dielectric layer, depositing a hardmask material on said dielectric layer, thereby forming a hardmask layer, said hardmask layer having a top surface; forming at least one opening in said dielectric layer; filling said opening with a conductive material, thereby forming at least one conductor, said conductor having a surface coplanar with the top surface of said hardmask layer; depositing a first material on said conductor, thereby forming a first cap layer, wherein said first material is deposited by a high density plasma chemical vapor deposition (HDP CVD) process; and depositing a second material on said first cap layer, thereby forming a second cap layer, wherein said second material is deposited by a plasma-enhanced chemical vapor deposition (PE VCD) process. 2794

293 [72] SCORCH PREVENTION IN FLEXIBLE POLYURETHANE FOAMS Int. Cl.8 C08G 018/02, C08J 009/04 BROMINE COMPOUNDS LTD. SAMUEL BRON, ARIEL SLUSZNY, DORIT PELED, DORIT PERLE LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA מניעת דהיה בקצפים פוליאורתניים גמישים תרכובות ברום בע"מ, באר שבע שמואל ברון, אריאל סלושני, דורית פלד, דורית פרלה לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] An anti-scorch composition for flame-retarded flexible polyurethane foams, comprising, in combination, one or more antioxidant agents, one or more metal salts of monocarboxylic or dicarboxylic acids, an epoxy compound, and at least one organic phosphite [31] [72] [87] MILLING TOOL GM972/2001 [32] Int. Cl.8 B23C 005/20 CERATIZIT AUSTRIA GESELLSCHAFT M.B.H, AUSTRIA UWE SCHLEINKOFER, JUERGEN DUWE, WOLFGANG KOCH WO/2003/ EITAN MEHULAL LAW GROUP, 10 ABBA EBEN BLVD., P.O. B. 2081, HERZLIYA מכשיר שיבוב [33] AT קבוצת איתן מהולל, עורכי דין ועורכי פטנטים, שדרות אבא אבן, 10 ת.ד. 2081, הרצליה [57] A milling tool for milling workpiece surfaces, the milling tool having a rotational axis and comprising: one or more cutting segments, each with a cutting edge geometry including a main cutting edge, a cutting corner, and a secondary cutting edge; said cutting 2795 segments being formed such that a generatrix of an envelope curve described by a rotation of the milling tool includes a cutting corner portion, a first segment adjoining said cutting corner portion, and a second segment adjoining said first segment; said first segment having a projection length of

294 at least 1 mm, in a projection thereof onto the axis of rotation, lying nearest to the rotational axis at a beginning point bordering said cutting corner, and lying farthest from the rotational axis at an end point distal from said cutting corner, and wherein a tangent at each point within said first segment encloses an angle α 1 in a range of 0 o to 5 o with a parallel to the rotational axis; said second segment having a projection length of at least 1.5 mm, in a projection thereof onto the axis of rotation, lying, farthest from the rotational axis at a beginning point thereof bordering on said first segment, lying nearest to the axis of rotation at an end thereof, and wherein a tangent at each point of said second segment encloses an angle α 2 in a range from >0 o to 3 o with the parallel to the rotational axis and the angle α 2 increases progressively toward the end of said second segment; and said projection length of said second segment being at least 1.5 times greater than said projection length of said first segment. [31] [87] MATT POLYMERIC ADHESIVE [32] Int. Cl.8 C08K 007/10, C09J 011/04 ROHM GMBH & CO. KG, GERMANY WO/2004/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] DE דבק פולימרי בעל מראה עמום ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A polymeric adhesive comprising the following additives: (a) silica powder having an average particle size of from 1 µm to 10 µm (matting agent); and (b) silica powder having an average particle size of more than 10 µm up to 200 µm (texturing agent). 2796

295 METHOD OF CREATING HIGH- QUALITY RELAXED SIGE-ON- INSULATOR FOR STRAINED SI CMOS APPLICATIONS שיטת יצור של מבדד על SiGe שהינו באיכות גבוהה ורפה לישומים CMOS עם Si הדוק [31] [87] [32] Int. Cl.8 H01L 021/20 IBM CORPORATION, U.S.A. WO/2003/ IBM LABORATORIES, HAIFA UNIVERSITY, HAIFA [33] US מעבדות יבמ מחלקת קנין רוחני, אוניברסיטת חיפה הר הכרמל, חיפה [57] A substrate material comprising: a Si-containing substrate (10); an insulating region (12) that is resistant to Ge diffusion present atop said Sicontaining substrate; and a substantially relaxed SiGe layer present atop said insulating region, wherein said substantially relaxed SiGe layer has a thickness of about 2000 nm or less. WHEELCHAIR CAPABLE OF CLIMBING AND DESCENDING STAIRS Int. Cl.8 A61G 005/06, B62B 009/06 EFIM LAPATIN OLGA LAPATIN EFIM LAPATIN, 42/1 UZIEL ST., RAMAT GAN עגלת נכים בעלת יכולת לעלות ולרדת במדרגות יפים לפטין, רמת גן אולגה לפטין, רמת גן יפים לפטין, רח' עוזיאל 42 דירה 1, רמת גן [57] Wheelchair, able to climb and descend stairs comprising: a frame (1) having a seat (2) for an occupant (3); an axle (7) connected to the frame, 2797 transversely relative to wheelchair, spiders (8) set on the axle on the both sides of the frame with possibility of a turn relative to the axle, said driving

296 spiders each having at least three evenly spaced radial legs (13), bidirectional drive to rotate the axle with the spiders, main running wheels (4) linked with the radial legs of the spider and used for moving the wheelchair both over stairs and across a level bearing surface (6); a means for locking and unlocking the main running wheels relative to the spider, the said means comprising a brake unit and a projection (10) fixed on the axle, two stops (11, 12) fixed on the spider and interacting with the projection and a kinematic unit linking the spider with each main running wheel and providing for pressing of these wheels to the brake unit by rotating of the spider, ensuring a movement of the wheelchair over stairs during setting in motion the bidirectional drive, the said means ensuring a movement of the wheelchair on a level bearing surface during cutting out the bi-directional drive, under acting of the wheelchair's weight drawing to each main running wheel away from the brake unit of the spider turned by the wheels due to kinematic units, getting the wheels in contact with each other and drawing the stop away from the stopped projection, auxiliary running wheel (21) used for moving and turning the wheelchair on level bearing surface, said auxiliary running wheel linked with the frame and freely rotatable to the axis perpendicular to the seat. 2798

297 [31] [87] COMPONENT SUPPORT AND RADIOISOTOPE GENERATOR INCLUDING ONE OR MORE COMPONENT SUPPORTS [32] Int. Cl.8 F16B 021/06, G21F 005/00 GE HEALTHCARE LIMITED, UNITED KINGDOM WO/2003/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] מערכת תמיכה לרכיב ומערכת יצור רדיואיזוטופים הכוללת מערכת תמיכה אחת או יותר לרכיבים GB ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A component support (29) for use in a radioisotope generator, the component support comprising a latching member (5) movable between an engaging position and an open position characterised by further including a bracing member (13) mechanically associated with the latching member and adapted to prevent movement of the latching member to the open position. 2799

298 [31] [72] [87] AUTO-FOCUSING METHOD AND DEVICE [32] Int. Cl.8 G02B 007/04 YEDA RESEARCH AND DEVELOPMENT CO. LTD. BENJAMIN GEIGER, ZVI KAM WO/2003/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] IL שיטה והתקן למיקוד עצמי ידע חברה למחקר ופיתוח בע"מ, רחובות בנימין גייגר, צבי קם ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] An auto-focusing method for determining an in-focus position of a sample supported on one surface of a substrate plate made of a material transparent with respect to incident electromagnetic radiation, the method utilizing an optical system capable of directing incident electromagnetic radiation towards the sample and collecting reflections of the incident electromagnetic radiation which are to be detected, and comprising: (i) locating a focal plane of an objective lens arrangement at a predetermined distance from a surface of the substrate, which is opposite to said surface supporting the sample; (ii) providing continuous displacement of the focal plane relative to the substrate along the optical axis of the objective lens arrangement, while concurrently directing the incident radiation towards the sample through the objective lens arrangement to thereby focus the incident radiation to a location at the focal plane of the objective lens arrangement; and (iii) continuously detecting reflected components of the electromagnetic radiation collected through said objective lens arrangement, said detected reflected components being characterized by a first intensity peak corresponding to an in-focus position of said opposite surface of the substrate, and a second intensity peak spaced in time from the first intensity peak and corresponding to an in-focus position of said sample-supporting surface of the substrate, thereby enabling imaging of the sample when in the in-focus position of the samplesupporting surface of the substrate. 2800

299 [31] [87] HYDRAULIC ROTARY- PERCUSSIVE HAMMER DRILL /03402 [32] Int. Cl.8 B25D 017/24 MONTABERT S.A., FRANCE WO/2003/ LUZZATTO & LUZZATTO, INDUSTRIAL PARK, OMER, P.O.B. 5352, BEER-SHEVA [33] מקדח פטיש נוקש סובב הידראולי FR לוצאטו את לוצאטו, גן תעשייה, עומר, ת.ד. 5352, באר שבע [57] A hydraulic rotary percussive hammer drill (1) comprising a body (2) containing a reciprocating percussion piston (4) sliding under the effect of a main hydraulic supply circuit, this main circuit also being intended to cause the sliding of a roughly annular abutment piston (5) housed in a cavity (3) of the body, and having, on the one hand, a front face (13) intended to position a shank (7) a predetermined distance away from the percussion piston and, on the other hand, a rear face (14) facing a rear wall of the cavity, wherein: an external hydraulic supply circuit (23) is able, when the main circuit (22) is shut down, to introduce fluid under pressure between the rear face of the abutment piston and the rear wall of the cavity so as to maintain a space between these items; and the external circuit opens into the rear end of the cavity and in that a sliding annular sleeve is placed around a rear part of the abutment piston and is able, on the one hand, to prevent the introduction of the fluid delivered by the external circuit when a pressure in a rear chamber (17) is above or equal to a predetermined value and, on the other hand, to allow this fluid to be introduced when the pressure in the rear chamber is below the determined value. 2801

300 DECANTER CENTRIFUGE WITH WEAR REINFORCEMENT INLET צנטריפוגת יציקה בעלת פתח כניסה עם חיזוק למניעת שחיקה [31] [87] PA 2002 [32] Int. Cl.8 B04B 001/20 ALFA LAVAL COPENHAGEN A/S, DENMARK WO/2003/ SELIGSOHN GABRIELI & CO., 31 YAVNE ST., P.O.B. 1426, TEL AVIV [33] DK זליגסון גבריאלי ושות', רח' יבנה, 31 ת.ד. 1426, תל אביב [57] A decanter centrifuge with a hollow drum having a longitudinal axis of rotation and a direction of rotation, a screw conveyor in the drum comprising a core body (1) carrying at least one helical winding (2) wherein an inlet chamber (3) is provided in the core body, said inlet chamber having an inlet opening for inlet of material into the drum from the inlet chamber, a central inlet being provided in the inlet chamber as well as an end wall (13) in the inlet chamber opposite the central inlet, the inlet opening having a delimitation surface (7) which is rear relative to the direction of rotation and extending substantially axially, said delimitation surface being provided with a wear reinforcement (8) and a preferably substantially tangentially extending edge (13a), which is distal relative to the central inlet, characterized in that the wear reinforcement comprises a wear 2802

301 reinforcement member extending along the rear delimitation surface and, when viewed in section transverse to the direction of the axis of rotation, extending around the rear delimitation surface, the wear reinforcement member extending so far into the inlet chamber along its wall that a concave back surface of the wear reinforcement member facing the rear delimitation surface has an interior portion in the inlet chamber, said portion being positioned behind the foremost point of the rear delimitation surface viewed relative to the direction of rotation, that the wear reinforcement member is provided with an abutment surface with a component facing tangentially opposite the back surface in abutment against an abutment surface associated with the core body and which during operation prevents the wear reinforcement member from moving tangentially forwards in the direction of rotation, and an abutment surface with a radially outwards facing component in abutment against an abutment surface associated with the core body preventing the wear reinforcement member from moving radially out of the core body, that at least one of said abutment surfaces associated with the core body is constituted by a removable blocking member and that the wear reinforcement member and the inlet opening are designed in such a manner that the wear reinforcement member can be introduced to its operating position from the exterior side of the core body. [31] [87] 2803 AQUATIC ANIMAL FEED CONTAINING MICROALGAE CONTAINING ARACHIDONIC ACID /365,182 [32] Int. Cl.8 A23K 001/00, 001/18 ADVANCED BIONUTRITION CORPORATION, U.S.A. WO/2003/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] מאכל לחיות ים המכיל מיקרואצות המכילות חומצת אראחידונית US וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים

302 [57] A feed for an animal comprising one or more microalgae or portions thereof which comprise arachidonic acid, wherein the microalgal arachidonic acid comprises from about 1% to about 20% of the feed, and wherein the arachidonic acid is predominantly in a triglyceride form and wherein the microalgae is chosen from one or more of Euglena, Parietochloris, or snow algae SHUTTER DEVICE WITH FLEXIBLE LATERAL EDGES התקן סגירה עם קצוות גמישים [31] [87] /0197 [32] Int. Cl.8 E06B 009/58 DYNACO INTERNATIONAL S.A., BELGIUM WO/2003/ EITAN, PEARL, LATZER AND COHEN ZEDEK, P.O.B , HERZLIYA [33] BE איתן, פרל, לצר וכהן צדק, רחוב שנקר, 7 ת.ד , הרצליה [57] Shutter device intended to close a bay or other opening, with flexible edges projecting with respect to the plane of the shutter and collaborating with guideways (4, 5), at least one reintroduction element (12) being provided, allowing the said edges to be reintroduced into the guideways when these edges become disengaged from the latter under the action of a force exerted on these edges in a direction transverse to the guideways, a contact area being formed during this reintroduction between the reintroduction element and the corresponding edge, characterized in that the lateral edges (2, 3) consist at least partially of an elastomeric material so that the said contact area increases as the said force increases, spreading this force over the contact area. 2804

303 REVERSIBLE SPEED VARIATOR Int. Cl.8 F16H 009/26, 015/18 OLGA LAPATIN EFIM LAPATIN EFIM LAPATIN, 42/1 UZIEL ST., RAMAT GAN וריאטור המהירות עם מהלך אחורי אולגה לפטין, רמת גן יפים לפטין, רמת - גן יפים לפטין, עוזיאל 42 דירה 1, רמת - גן [57] A reversible speed variator comprising: a case (1), a driving (2) and driven (4) shaft, a differential fixed on a supporting shaft and having two driving conical gears (8, 9) and a driven axle (10) is perpendicular to the supporting shaft and having two driving conical gears (8, 9) and driven axle (10) is perpendicular to the supporting shaft and carrying two conical gears (11) engaged with driving conical gears, the driving conical gears linked with the driving shaft by an unregulable and regulable kinematic chain having odd and even quantity of external engagements, the supporting shaft linked kinematically with the driven shaft, a splined hollow shaft attached to the driving conical 2805 gear and having roller supports put in the case, a mobile wheel (14) put on splined hollow shaft (13) and mounted rotatably in a protective shroud linked with a longitudinal transference mechanism, a conical drum (35) with an inclined revolution axis having a lower forming line is parallel to the splined hollow shaft, the mobile wheel, having friction engagement with conical drum along the lower forming line, the mobile wheel, having an external diameter more than a small diameter and less than a big diameter of the conical drum, a conical drum put between a cardan and a tiltable support provided with a lifting mechanism, a means, providing a dry friction between the mobile

304 wheel and the conical drum, having the protective shroud and a folding shroud for the conical drum connected with the protective shroud. SEMI-SYNTHETIC PROCESS FOR THE PREPARATION OF N- DEBENZOYLPACLITAXEL תהליך סינטטי למחצה להכנת N דבנזואילפאקליטאקסל [31] [87] MI2002A [32] [33] IT Int. Cl.8 C07D 305/00, 305/14, 405/12, 405/14, 407/12 INDENA S.P.A., ITALY WO/2003/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., רחוב אחד העם, 21 ת.ד. 4060, תל P.O.B. 4060, אביב TEL AVIV [57] A process for the preparation of N-debenzoylpaclitaxel of the formula which comprises: (a) condensing a carboxylic acid, or a salt or an activated derivative thereof of the formula 2806

305 in which R1 is an aryl or heteroaryl group, with a baccatin derivative of the formula in which R2 is a hydroxy-protecting group removable by acid-catalyzed solvolysis, to give a compound of the formula in which R1 and R2 are as defined above; (b) removing the R2 group and opening the oxazolidine ring in the compound of formula (IV) by acid-catalyzed solvolysis. 2807

306 [31] [87] PESTICIDE COMPOSITIONS AND METHODS FOR PREVENTING OR REDUCING RESISTANCE TO A PESTICIDE OF A SUBSTRATE PEST [32] Int. Cl.8 A01N 025/00, 025/06, 053/08 ROTHAMSTED RESEARCH LIMITED, UNITED KINGDOM DEPARTMENT OF PRIMARY INDUSTRIES FOR AND ON BEHALF OF THE STATE OF NEW SOUTH WALES, AUSTRALIA WO/2003/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV תכשירים קוטלי חרקים ושיטות למניעת או הפחתת העמידות לקוטלי חרקים של מזיקי מצע [33] GB ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A method for preventing or reducing resistance to a pesticide of a substrate pest, which method comprises the administration to the substrate or the pest of a composition comprising: (a) a rapid-release formulation of an inhibitor of a factor causing or contributing to the resistance of the pest to the pesticide, the inhibitor being a metabolic enzyme inhibitor; and, substantially simultaneously, (b) a non-rapid release formulation of the pesticide. [31] [87] CHILD-RESISTANT BLISTER PACK / [32] Int. Cl.8 B65D 083/04 R.P. SCHERER TECHNOLOGIES, INC., U.S.A. WO/2003/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] תפיסה של טבליות עמידה בפני ילדים US ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב 2808

307 [57] A child-resistant blister pack that enables separating a plurality of dosage units (10) in a particular order, said pack comprising: (i) a blister film sheet (12) with depressions (16) therein; (ii) dosage forms within the depressions; (iii) a lidding sheet (14) which overlies the depressions and which is secured to the film sheet so as to seal the dosage forms within the depressions; and (iv) a network of lines of weakness (26) in the pack defining the plurality of dosage units, each dosage unit including (a) one of said dosage forms sealed in one of the depressions covered by the lidding sheet and (b) a peel region (40) where part of the lidding sheet is not secured to the blister film sheet, each peel region being disposed adjacent a respective one of the lines of weakness in the network; wherein said lines of weakness include; a first line of weakness (26) extending from a first access point (35) so that, when the first access point is exposed, the blister film sheet and the lidding sheet can be torn along the first line of weakness to expose a second access point (36) wherein the second access point enables access to only a second line of weakness (27) and also to enable access to the peel region of a first dosage unit (18) wherein the second line of weakness extending from the second access point so that, when the second access point is exposed, the blister film sheet and the lidding sheet can be torn along the second line of weakness to expose a third access point (56a) wherein the third access point enables access to only a third line of weakness and also to enable access to the peel region of a second dosage unit (19); and wherein the third line of weakness which is spaced from the first line of weakness and which extends from the third access point so that, when the third access point is exposed, the blister film sheet and the lidding sheet can be torn along the third line of weakness to enable access to the peel region of a third dosage unit. 2809

308 TARGETING SYSTEM COMPRISING UNIFORMLY- SIZED NANOPARTICLES WITH AT LEAST ONE POLYMER AND AT LEAST ONE POSITIVELY CHARGED POLYSACCHARIDE AND PREPARATION METHOD THEREOF מערכת העברה למטרה המכילה נאנו חלקיקים של גודל אחיד של לפחות פולימר אחד ושל לפחות פוליסככריד אחד מוטען באופן חיובי ושיטה להכנתה [31] [87] /07668 [32] Int. Cl.8 A61K 009/00, 009/51 BIOALLIANCE PHARMA, FRANCE WO/2004/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] FR סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] Vectorization and delivery system of nanoparticles present a homogeneous substances of therapeutic or diagnostic distribution of size and comprise (i) at least interest, of the type constituted by one polymer and (ii) at least one nontoxic nanoparticles, characterized in that said positively charged polysaccharide. PROCESS AND RIBBED TUBE FOR THERMALLY CLEAVING HYDROCARBONS תהליך וצינור מצולע לבקיעה תרמית של פחמימנים [31] [87] [32] Int. Cl.8 C10G 009/00, F28F 001/40 SCHMIDT +CLEMENS GMBH+CO. KG, GERMANY WO/2004/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] DE וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים [57] A finned tube for the thermal cracking of hydrocarbons in the presence of steam, in which the charge mixture is passed through externally heated tubes having a plurality of helically running inner fins, characterized in that the flank angle of the fins is 16 o to 25 o and the fins run at an angle of 20 o to 40 o with respect to the tube axis. 2810

309 BIOMIMETIC MEMBRANES ממברנות ביומימטיות [31] [87] / [32] [33] US 60/ US Int. Cl.8 A01N 001/00, B01D 053/84, 069/14, 071/80, C12N 001/00 MT TECHNOLOGIES, INC., U.S.A. WO/2004/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A biomimetic membrane, comprising: a tri-block copolymer matrix simulating a natural biological membrane and natural protein environment; and membrane proteins incorporated into said matrix to form a membrane/protein composite. 2811

310 [31] [87] METHOD FOR PRODUCING AN AVOCADO UNSAPONIFIABLE MATERIAL RICH IN FURAN LIPIDS PCT/FR02/02715 [32] / Int. Cl.8 A61K 003/ /65400 LABORATOIRES EXPANSCIENCE, FRANCE WO/2004/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] שיטה להכנת חומר עשיר בפוראן ליפידי שאינו הופך לסבון WO US ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] Process for obtaining a furan lipidrich unsaponifiable material from avocado, comprising: (I) controlling dehydration of fresh avocados or of avocados that have undergone a preliminary transformation, wherein the dehydration is performed at a temperature of between -50 o C and 75 o C, (II) extracting oil from dehydrated fruit, (III) alternatively, (a) heat treating the extracted oil at a temperature from 80 to 150 o C, and then concentrating the unsaponifiable fraction of the oil, or (b), concentrating the unsaponifiable fraction of the oil, followed by heat treating at a temperature from 80 to 150 o C, followed by (IV) saponificating and extracting of the unsaponifiable material wherein the concentrating of (III)a or (III)b is molecular distillation at a temperature of between 180 and 260 o C or cold crystallization [31] [87] DISH ASSEMBLY [32] Int. Cl.8 F24J 002/12 ROBERT EDGAR WHELAN, AUSTRALIA WO/2004/ DR. MARK FRIEDMAN LTD., MOSHE AVIV TOWER, 54TH FLOOR, 7 JABOTINSKY ST., RAMAT GAN [33] AU מכלול צלחת ד"ר מרק פרידמן בע"מ, מגדל משה אביב, ק. 54, רח ז'בוטינסקי 7, רמת- גן 2812

311 [57] A dish assembly (10) including:- a central hub (11); an outer rim member (12), and a plurality of concentric arcuate structural members (13) extending from the central hub to the outer rim member; the arcuate members being of box-section configuration and abutting along their inner and outer arcuate surfaces such that load can be transferred from an outer arcuate structural member to an inner arcuate structural member [62] POLYURETHANE/UREA COMPOSITIONS Int. Cl.8 C08G 002/00, 018/32 Division from KENNETH I. SAWYER, U.S.A. REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV הרכבי פוליאורתאן/אוריאה ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A moisture curable, storage stable, single component polyurethane/urea composition comprising (i) polyaminobenzoates or polyaminobenzamides of the formula wherein at least one of the aromatic amino groups is blocked by reaction with aldehyde; n is 2813 an integer from 2 to 4; each k is one or two; each benzoyl nucleus is para, meta, or di-meta-aminosubstituted; each Z is O-or

312 NR-; G is a n-valent radical obtained by removal of hydroxy groups or amino groups from an n-valent polyol or polyamine having a molecular weight of from about 200 to about 6,000; and R is hydrogen or selected from the group consisting of C 1 -C 20 alkyl, [(C 1 -C 20 alkoxy) aryl] methyl and [(C 1 -C 20 alkyl) aryl] methyl; (ii) organic polyisocyanate or blocked organic polyisocyanate; and optionally (iii) a catalyst for accelerating curing, auxiliary agents and/or additives. CATHETER BALLOON HAVING IMPROVED BALLOON BONDING צנתר בלון בעל תקשיר בלון משופר [31] [87] / [32] Int. Cl.8 A61M 025/10 ADVANCED CARDIOVASCULAR SYSTEMS, INC., U.S.A. WO/2004/ WOLFF, BREGMAN AND GOLLER, P.O.B. 1352, JERUSALEM [33] US וולף, ברגמן וגולר,, ת.ד. 1352, ירושלים [57] A balloon catheter (10) comprising: (a) an elongated shaft (12) having a proximal end, a distal end, and an inflation lumen (22); and (b) a balloon (24) on a distal shaft section, having an interior in fluid communication with the inflation lumen of the shaft, and having a proximal (25) and a distal skirt (26) section bonded to the shaft and an inflatable section (32) therebetween, and a polymeric first layer (33) and a polymeric second layer (34) extending from the proximal skirt section to the distal skirt section, the first layer having an inner surface which has at least a section which is gas plasma-etched or chemical solutionetched and an outer surface which has at least a section which is gas plasma-etched or chemical solution-etched. 2814

313 [31] [62] [87] PRINTER WITH A BINDING ASSEMBLY PQ0559 [32] PQ PQ Int. Cl.8 B41J 029/00 Division from SILVERBROOK RESEARCH PTY. LTD., AUSTRALIA WO/2000/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] AU AU AU מדפסת עם מכלול קישור ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] A printer (601) which includes: a support structure that defines a print media feed path; a print media feed mechanism mounted on the support structure for feeding sheets of print media along the feed path; a printhead assembly (706) mounted on the support structure to carry out a printing operation on the sheets of print media; a binding assembly (605) mounted on the support structure downstream of the printhead assembly, the binding assembly including: a glue application means positioned downstream of the printhead assembly to apply glue to each sheet of print media; and a platen assembly that is positioned downstream of the glue application means, the platen assembly having a support platen that is positioned to receive and support each printed sheet and a binding platen that is reciprocally displaceable with respect to the support platen to displace a printed sheet (64) onto the support platen and to urge said sheet against a preceding sheet so that the sheets are glued together. 2815

314 PORTABLE ELECTRIC POOL CLEANER מנקה בריכה חשמלי הניתן להשאה [31] [87] / [32] Int. Cl.8 E04H 004/16 WATER TECH LLC, U.S.A. WO/2004/ SANFORD T.COLB & CO., P.O.B. 2273, REHOVOT [33] US סנפורד ט. קולב ושות', שער הגיא 4, מרמורק, ת.ד. 2273, רחובות [57] A hand-held submersible electrically-powered pool cleaner (10) comprising: a nozzle (36); a toroidal body (16) having; a carrying handle (14) for carrying, manipulating, and directing the cleaner during use, with the carring handle being integrally formed from an upper portion of the toroidal body and an opening through the toroidal body; an impeller (82) and drive motor, and a filter (40); said body having an intake opening in fluid communication with the nozzle, wherein the impeller draws pool water through the nozzle and filter to remove dirt and debris from the pool water. 2816

315 [31] [87] PROCESS FOR THE RECYCLING OF SOLID PHASE BONDED CTC - RESIN [32] Int. Cl.8 C08F 002/00, 008/20 F. HOFFMANN-LA ROCHE AG, SWITZERLAND WO/2004/ REINHOLD COHN AND PARTNERS, 21 AHAD HA'AM ST., P.O.B. 4060, TEL AVIV [33] תהליך למיחזור של שרף CTC הקשור למוצק EP ריינהולד כהן ושותפיו, רחוב אחד העם, 21 ת.ד. 4060, תל אביב [57] Process for the preparation of solid phase bonded 2-chlorotrityl chloride (2- CTC resin) of the formula wherein Ps is a polymeric support and n has the following meaning: 1 n 0 comprising the reaction of solid phase bonded 2-chlorotrityl of the formula I 2817

316 wherein R is OH or/and OC 1-4 -alkyl or/and NR'R" wherein R' and R" independently of each other represent C 1-4 -alkyl, or R' and R" together with the nitrogen to which they are bonded represent a 5 to 8 membered heterocyclic radical, in the presence of HCl and an organic solvent. CONNECTION BETWEEN THE REAR END WALL OF A COMBUSTION CHAMBER AND THE NOZZLE OF A ROCKET ENGINE קישור בין סופו של קיר אחורי של תא בעירה ופתחו של מנוע של טיל [31] [87] /15158 [32] [33] FR Int. Cl.8 F02K 009/08, 009/34, F16J 015/08 SNECMA PROPULSION SOLIDE, FRANCE WO/2004/ LUZZATTO & LUZZATTO, לוצאטו את לוצאטו, INDUSTRIAL PARK, OMER, P.O.B. 5352, גן תעשייה, עומר, ת.ד. 5352, באר שבע BEER-SHEVA [57] A connection between the rear end wall (14) of a combustion chamber and a nozzle of a rocket engine, the connection comprising: mechanical connection means linking the nozzle to the end wall at least in an axial direction, together with a thermal barrier (40), and at least one sealing gasket (32) disposed in the interface (30) defined by the adjacent facing faces of the end wall and of the nozzle, the connection being characterized in that the thermal barrier comprises at least one refractory fiber fabric forming a cord (42) wound in the interface around the longitudinal axis (A) of the chamber, the cord(s) being made in such a manner as to ensure circumferential continuity of the thermal barrier. 2818

317 LOCAL AREA NETWORK OF SERIAL INTELLIGENT CELLS LAN של תאים אינטיליגנטים סדרתיים [31] [62] [72] [87] / [32] [33] US Int. Cl.8 H04B 003/54, H04J 003/08, 004/00, H04L 005/14, 012/28, H04M 011/06 DIVISION FROM SERCONET LTD. סרקונט בע"מ, רעננה YEHUDA BINDER יהודה בינדר WO/2000/ REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., P.O.B. 4060,, 21 ת.ד. 4060, תל אביב רחוב אחד העם TEL AVIV [57] A network for remotely coupling a computer plug-in card to a computer over a wiring, said network comprising: wiring carrying bidirectional serial digital data; a first device housed, in a first enclosure, connected to said wiring and connectable to a computer via an interface, said first device being operative for coupling the serial digital data to the computer; and a second device, housed in a second enclosure, connected to said wiring, said second device comprising a bus slot and being operative for mechanically and electrically interfacing a computer bus plug-in card and coupling serial digital data to the plug-in card. The applications for division from this application have not yet been published,189508, בקשות חלוקה מבקשה זו שטרם פורסמו. 2819

318 DEVICE FOR THE CONTINUOUS PRODUCTION OF A NONWOVEN WEB התקן לייצור רציף של רשת בלתי ארוגה [31] [32] [33] DE EP Int. Cl.8 D01D 005/088, 005/098, D04H 003/16 REIFENHAUSER GMBH & CO. KG MASCHINENFABRIK REINHOLD COHN AND PARTNERS, ריינהולד כהן ושותפיו, 21 AHAD HA'AM ST., רחוב אחד העם, 21 ת.ד. 4060, תל P.O.B. 4060, אביב TEL AVIV [57] Device for the continuous production of a nonwoven web from filaments made from a thermoplastic synthetic, with a spinning nozzle (1), a cooling chamber (2), a stretching unit (4) and a depositing device for depositing filaments to the nonwoven web, whereby two or more different polymer fusions can be fed to the spinning nozzle and whereby a device is provided for merging the different polymer fusions such that bi-component filaments and multi-component filaments exit from the spinning nozzle openings of the spinning nozzle and whereby the cooling chamber is divided into the least two cooling chamber sections (2a, 2b) in which the bi-component filaments and multicomponent filaments respectively come into contact with process air with different convective heat discharge means. 2820

319 CLEANABLE HAIR BRUSH Int. Cl.8 A46B 009/10 DAVID ABODREHAM DR. EYAL BRESSLER, 11 TUVAL ST., RAMAT GAN מברשת שיער ניתנת לניקוי דוד אבודרהם, הרצליה דר' אייל ברסלר עו"פ, תובל 11, רמת - גן [57] A cleansable hairbrush, comprising a basal surface from which a plurality of bristles are extending upwardly; and a rotatable cleansing sieve (30) wherein said sieve is rotatably mounted in a housing (20) located adjacent to said basal surface; said sieve comprising a plurality of apertures, each of which is accommodating at least one bristle; said sieve is adapted to rotate in a course providing a closed configuration, i.e., whereat the sieve is fastened parallel to the basal surface, and an open configuration i.e., whereat the sieve is tilted from said basal surface and provides for efficient removal of hair or litter from the said basal surface. 2821